Journal ArticleDOI
Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children
Andrew J. Wakefield,S. H. Murch,A Anthony,J Linnell,D M Casson,M Malik,M Berelowitz,Ap Dhillon,Mike Thomson,Peter Harvey,A Valentine,S Davies,J A Walker-Smith +12 more
TLDR
In this paper, the authors investigated a consecutive series of children with chronic enterocolitis and regressive developmental disorder, and identified associated gastrointestinal disease and developmental regression in a group of previously normal children, which was generally associated in time with possible environmental triggers.About:
This article is published in The Lancet.The article was published on 1998-02-28. It has received 2505 citations till now. The article focuses on the topics: Pervasive developmental disorder & Lymphoid hyperplasia.read more
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Inflammatory bowel disease and autism
TL;DR: These data provide no support for the hypothesis of an association between Crohn’s disease and autism, and are consistent with published prevalence estimates of IBD3s4 and argues against the possibility that IBD would have been underdetected in these samples.
Journal ArticleDOI
Serum levels of platelet-derived growth factor BB homodimers are increased in male children with autism.
Masanobu Kajizuka,Taishi Miyachi,Hideo Matsuzaki,Hideo Matsuzaki,Keiko Iwata,Chie Shinmura,Katsuaki Suzuki,Shiro Suda,Kenji J. Tsuchiya,Kaori Matsumoto,Yasuhide Iwata,Kazuhiko Nakamura,Masatsugu Tsujii,Masatsugu Tsujii,Toshiro Sugiyama,Nori Takei,Norio Mori +16 more
TL;DR: Estimated levels of serum PDGF-BB homodimers might be implicated in the pathophysiology of autism, and there were no marked or significant correlations between serum levels and clinical variables, including the other ADI-R scores and Intellectual Quotient scores by WAIS-R.
Vaccines for measles, mumps and rubella in children (Review)
Demicheli,Jefferson T +1 more
TL;DR: The design and reporting of safety outcomes in MMR vaccine studies, both pre- and post-marketing, are largely inadequate and the evidence of adverse events following immunisation with MMR cannot be separated from its role in preventing the target diseases.
Journal ArticleDOI
Mismatches between 'scientific' and 'non-scientific' ways of knowing and their contributions to public understanding of science
TL;DR: The failure of effective communications between scientists and non-scientists has hindered the progress of both effective science and effective policy, and renewed efforts must be made to encourage substantive public engagement.
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Highly cited retracted papers
TL;DR: The number of citations in 10 highly cited retracted papers is examined, and their current pre- and post-citation values are compared, to offer some possible explanations for the continued citation.
References
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Journal ArticleDOI
Alpha-1-antitrypsin, autism, and cœliac disease
Book
The Autistic Spectrum
TL;DR: A simple system of subgrouping based solely on a description of the type of social impairment will be used, which avoids the confusion inherent in trying to identify the named syndromes.
Journal ArticleDOI
Abnormal intestinal permeability in children with autism.
Patrizia D'Eufemia,Mauro Celli,R. Finocchiaro,Lucia Pacifico,L Viozzi,M. Zaccagnini,Ettore Cardi,Omero Giardini +7 more
TL;DR: It is speculated that an altered intestinal permeability could represent a possible mechanism for the increased passage through the gut mucosa of peptides derived from foods with subsequent behavioural abnormalities.
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A neurochemical theory of autism
TL;DR: Panksepp et al. as discussed by the authors put forward the idea that autism is an emotional disturbance arising from an upset in the opiate systems in the brain, and hence proposed, as a possibility, opiate antagonist therapy for the autistic syndrome.