Journal ArticleDOI
Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children
Andrew J. Wakefield,S. H. Murch,A Anthony,J Linnell,D M Casson,M Malik,M Berelowitz,Ap Dhillon,Mike Thomson,Peter Harvey,A Valentine,S Davies,J A Walker-Smith +12 more
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In this paper, the authors investigated a consecutive series of children with chronic enterocolitis and regressive developmental disorder, and identified associated gastrointestinal disease and developmental regression in a group of previously normal children, which was generally associated in time with possible environmental triggers.About:
This article is published in The Lancet.The article was published on 1998-02-28. It has received 2505 citations till now. The article focuses on the topics: Pervasive developmental disorder & Lymphoid hyperplasia.read more
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Journal ArticleDOI
Vaccine hesitancy, vaccine refusal and the anti-vaccine movement: influence, impact and implications
TL;DR: Determinants of parental decision-making about vaccination are looked at and an overview of the history of anti-vaccination movements and its clinical impact is provided.
Journal ArticleDOI
A Population-Based Study of Measles, Mumps, and Rubella Vaccination and Autism
Kreesten Meldgaard Madsen,Anders Hviid,Mogens Vestergaard,Diana Schendel,Jan Wohlfahrt,Poul Thorsen,Jørn Olsen,Mads Melbye +7 more
TL;DR: A retrospective cohort study of all children born in Denmark from January 1991 through December 1998 finds that vaccination against measles, mumps, and rubella (MMR) is a cause of autism.
Proceedings ArticleDOI
The Science of Science
Dashun Wang,Lu Liu +1 more
TL;DR: SciSci has revealed choices and trade-offs that scientists face as they advance both their own careers and the scientific horizon, and offers a deep quantitative understanding of the relational structure between scientists, institutions, and ideas, which facilitates the identification of fundamental mechanisms responsible for scientific discovery.
Journal ArticleDOI
Autism spectrum disorder
Catherine Lord,Traolach S. Brugha,Tony Charman,James C. Cusack,Guillaume Dumas,Thomas W. Frazier,Emily J.H. Jones,Rebecca M. Jones,Andrew Pickles,Matthew W. State,Julie Lounds Taylor,Jeremy Veenstra-VanderWeele +11 more
TL;DR: This Primer by Lord and colleagues reviews the epidemiology, mechanisms, clinical detection and treatment of autism and identifies the long-term needs of people with autism.
Journal ArticleDOI
Association of Hydroxyethyl Starch Administration With Mortality and Acute Kidney Injury in Critically Ill Patients Requiring Volume Resuscitation: A Systematic Review and Meta-analysis
Ryan Zarychanski,Ahmed M Abou-Setta,Alexis Turgeon,Brett L. Houston,Lauralyn McIntyre,John C. Marshall,Dean Fergusson +6 more
TL;DR: In critically ill patients requiring acute volume resuscitation, use of hydroxyethyl starch compared with other resuscitation solutions was not associated with a decrease in mortality and clinical use ofHydroxyethyl starch for acuteVolume resuscitation is not warranted due to serious safety concerns.
References
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Journal ArticleDOI
Alpha-1-antitrypsin, autism, and cœliac disease
Book
The Autistic Spectrum
TL;DR: A simple system of subgrouping based solely on a description of the type of social impairment will be used, which avoids the confusion inherent in trying to identify the named syndromes.
Journal ArticleDOI
Abnormal intestinal permeability in children with autism.
Patrizia D'Eufemia,Mauro Celli,R. Finocchiaro,Lucia Pacifico,L Viozzi,M. Zaccagnini,Ettore Cardi,Omero Giardini +7 more
TL;DR: It is speculated that an altered intestinal permeability could represent a possible mechanism for the increased passage through the gut mucosa of peptides derived from foods with subsequent behavioural abnormalities.
Journal ArticleDOI
A neurochemical theory of autism
TL;DR: Panksepp et al. as discussed by the authors put forward the idea that autism is an emotional disturbance arising from an upset in the opiate systems in the brain, and hence proposed, as a possibility, opiate antagonist therapy for the autistic syndrome.