Journal ArticleDOI
Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children
Andrew J. Wakefield,S. H. Murch,A Anthony,J Linnell,D M Casson,M Malik,M Berelowitz,Ap Dhillon,Mike Thomson,Peter Harvey,A Valentine,S Davies,J A Walker-Smith +12 more
TLDR
In this paper, the authors investigated a consecutive series of children with chronic enterocolitis and regressive developmental disorder, and identified associated gastrointestinal disease and developmental regression in a group of previously normal children, which was generally associated in time with possible environmental triggers.About:
This article is published in The Lancet.The article was published on 1998-02-28. It has received 2505 citations till now. The article focuses on the topics: Pervasive developmental disorder & Lymphoid hyperplasia.read more
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Proliferation of Papers and Preprints During the Coronavirus Disease 2019 Pandemic: Progress or Problems With Peer Review?
TL;DR: The nephrology community should embrace the pace of change, making deposition of research into preprint servers the default, encouraging pre-publication peer review more widely of such preprint studies, and harnessing social media tools to make these actions easier and seamless.
Journal ArticleDOI
US Immunization Policy.
TL;DR: The benefits of the vaccines in the recommended childhood immunization schedule are highlighted, the known risks of vaccinations are discussed, some of the current impediments to a maximally effective national immunization program are explored, and challenges that lie ahead are discussed.
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The safety of vaccines.
Derek T. O'Hagan,Rino Rappuoli +1 more
TL;DR: Widespread confidence will be inspired by the effective communication of the realities of the benefit-to-risk ratios for each vaccine, which will increase public confidence and ensure that vaccines become better appreciated as valuable products.
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Effects of Intravenous Secretin on Language and Behavior of Children With Autism and Gastrointestinal Symptoms: A Single-Blinded, Open-Label Pilot Study
Jenifer R. Lightdale,Cathy Hayer,Adam Duer,Christopher Lind-White,Sheila Jenkins,Bryna Siegel,Glen R. Elliott,Melvin B. Heyman +7 more
TL;DR: It is indicated that intravenous secretin had no effects in a 5-week period on the language and behavior of 20 children with autism and gastrointestinal symptoms, and no relationship was found between parental reports of change and observable improvement in the sample.
References
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Alpha-1-antitrypsin, autism, and cœliac disease
Book
The Autistic Spectrum
TL;DR: A simple system of subgrouping based solely on a description of the type of social impairment will be used, which avoids the confusion inherent in trying to identify the named syndromes.
Journal ArticleDOI
Abnormal intestinal permeability in children with autism.
Patrizia D'Eufemia,Mauro Celli,R. Finocchiaro,Lucia Pacifico,L Viozzi,M. Zaccagnini,Ettore Cardi,Omero Giardini +7 more
TL;DR: It is speculated that an altered intestinal permeability could represent a possible mechanism for the increased passage through the gut mucosa of peptides derived from foods with subsequent behavioural abnormalities.
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A neurochemical theory of autism
TL;DR: Panksepp et al. as discussed by the authors put forward the idea that autism is an emotional disturbance arising from an upset in the opiate systems in the brain, and hence proposed, as a possibility, opiate antagonist therapy for the autistic syndrome.