Lab-on-Chip Cytometry Based on Magnetoresistive Sensors for Bacteria Detection in Milk

TLDR: This work describes a platform for in-flow detection of magnetically labelled cells with a magneto-resistive based cell cytometer and presents an example for the validation of the platform as a magnetic counter that identifies and quantifies Streptococcus agalactiae in milk.

Abstract: Flow cytometers have been optimized for use in portable platforms, where cell separation, identification and counting can be achieved in a compact and modular format. This feature can be combined with magnetic detection, where magnetoresistive sensors can be integrated within microfluidic channels to detect magnetically labelled cells. This work describes a platform for in-flow detection of magnetically labelled cells with a magneto-resistive based cell cytometer. In particular, we present an example for the validation of the platform as a magnetic counter that identifies and quantifies Streptococcus agalactiae in milk.