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Neurophysiology and neuropharmacology of cardiovascular regulation and stress

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TLDR
The conclusion is reached that further multidisciplinary research will reveal underlying neurophysiological and neuropharmacological mechanisms responsible for stress induced cardiovascular disease and lead to new methods of treatment.
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This article is published in Neuroscience & Biobehavioral Reviews.The article was published on 1981-03-01. It has received 121 citations till now.

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How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions.

TL;DR: This review considers recent findings regarding GC action and generates criteria for determining whether a particular GC action permits, stimulates, or suppresses an ongoing stress-response or, as an additional category, is preparative for a subsequent stressor.
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Autonomic determinism: the modes of autonomic control, the doctrine of autonomic space, and the laws of autonomic constraint.

TL;DR: A formal 2-dimensional conception of autonomic space is proposed, and a quantitative model for its translation into a functional output surface is derived and has fundamental implications for the direction and interpretation of a wide array of psychophysiological studies.
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Interactions Between Cardiovascular and Pain Regulatory Systems

TL;DR: The present analysis suggests that the inhibition of pain brought about by elevations in either arterial or venous blood pressure may provide a form of psychophysiological relief under situations of stress and contribute to the development of essential hypertension in humans.
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Afferent and efferent connections of the A5 noradrenergic cell group in the rat.

TL;DR: In this article, the supraspinal afferent and efferent connections of the A5 noradrenergic cell group were examined in rats and very small deposits of HRP-WGA were made in the rostral A5 area.
References
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Journal ArticleDOI

Cardiac receptors in the dog, with particular reference to two types of afferent ending in the ventricular wall.

TL;DR: Experiments were described in which impulses were recorded in dogs from ventricular fibres with a cardiac rhythm of discharge, similar to those described by Paintal (1955) in the cat.
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Regulation of ventricular contraction. Influence of cardiac sympathetic and vagal nerve stimulation on atrial and ventricular dynamics.

TL;DR: Data from efferent stimulation of the vagus nerve and of the left stellate ganglion are believed to comprise a reasonably comprehensive description of the means available to the central nervous system for directly inducing acute changes in the activity of the heart.
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Participation of the anterior hypothalamus in the baroreceptor reflex

TL;DR: A depressor area has been defined, stimulation of which elicits a fall of arterial blood pressure and a bradycardia caused by inhibition of sympathetic vasomotor tone and by vagal activation respectively, accompanied by a reduction in rate and depth of respiration.
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The Trigeminal, Facial, Vagal, and Glossopharyngeal Nerves in the Monkey: Afferent Connections

TL;DR: The Nauta-Gygax technique was selected because it demonstrates degenerating nonmyelinated as well as myelinated axons and because it had not been used to trace the entering afferents of VII, IX and X in the monkey.
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Ascending projections of presumed dopamine-containing neurons in the ventral tegmentum of the rat as demonstrated by horseradish peroxidase

TL;DR: The results suggest that although there is considerable overlap, and that the same subdivisions within the substantia nigra pars compacta and the ventral tegmental area appear to innervate diverse regions of the forebrain, there also exists a general topographical organization with respect to the projections of these neurons.
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