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Neurophysiology and neuropharmacology of cardiovascular regulation and stress

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TLDR
The conclusion is reached that further multidisciplinary research will reveal underlying neurophysiological and neuropharmacological mechanisms responsible for stress induced cardiovascular disease and lead to new methods of treatment.
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This article is published in Neuroscience & Biobehavioral Reviews.The article was published on 1981-03-01. It has received 121 citations till now.

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How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions.

TL;DR: This review considers recent findings regarding GC action and generates criteria for determining whether a particular GC action permits, stimulates, or suppresses an ongoing stress-response or, as an additional category, is preparative for a subsequent stressor.
Journal ArticleDOI

Autonomic determinism: the modes of autonomic control, the doctrine of autonomic space, and the laws of autonomic constraint.

TL;DR: A formal 2-dimensional conception of autonomic space is proposed, and a quantitative model for its translation into a functional output surface is derived and has fundamental implications for the direction and interpretation of a wide array of psychophysiological studies.
Journal ArticleDOI

Interactions Between Cardiovascular and Pain Regulatory Systems

TL;DR: The present analysis suggests that the inhibition of pain brought about by elevations in either arterial or venous blood pressure may provide a form of psychophysiological relief under situations of stress and contribute to the development of essential hypertension in humans.
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Afferent and efferent connections of the A5 noradrenergic cell group in the rat.

TL;DR: In this article, the supraspinal afferent and efferent connections of the A5 noradrenergic cell group were examined in rats and very small deposits of HRP-WGA were made in the rostral A5 area.
References
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A functional study of distribution of cardiac sympathetic nerves.

TL;DR: It is concluded that the sympathetic cardiac nerves from the right side go primarily to the atria and nodal tissue, with a variable supply to the ventricles, while in some animals the latter supply is very large while in others it is minimal.
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Direct septo-hypothalamic projections in the rat.

TL;DR: These data indicate that a direct septo-hypothalamic pathway exists in the rat and project to the medial hypothalamic nuclei via a midline route while LSN axons projected strongly to the MSN with the remaining fibers coursing along the ipsilateral MFB to terminate in several hypothalamicuclei.
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Is the Area Postrema a Control Centre of Blood Pressure

TL;DR: There is evidence that some areas in the vicinity of the fourth brain ventricle mediate their effects and noradrenaline and γ-aminobutyric acid bring about a depression of the cardiovascular system.
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