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Neurophysiology and neuropharmacology of cardiovascular regulation and stress

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TLDR
The conclusion is reached that further multidisciplinary research will reveal underlying neurophysiological and neuropharmacological mechanisms responsible for stress induced cardiovascular disease and lead to new methods of treatment.
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This article is published in Neuroscience & Biobehavioral Reviews.The article was published on 1981-03-01. It has received 121 citations till now.

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How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions.

TL;DR: This review considers recent findings regarding GC action and generates criteria for determining whether a particular GC action permits, stimulates, or suppresses an ongoing stress-response or, as an additional category, is preparative for a subsequent stressor.
Journal ArticleDOI

Autonomic determinism: the modes of autonomic control, the doctrine of autonomic space, and the laws of autonomic constraint.

TL;DR: A formal 2-dimensional conception of autonomic space is proposed, and a quantitative model for its translation into a functional output surface is derived and has fundamental implications for the direction and interpretation of a wide array of psychophysiological studies.
Journal ArticleDOI

Interactions Between Cardiovascular and Pain Regulatory Systems

TL;DR: The present analysis suggests that the inhibition of pain brought about by elevations in either arterial or venous blood pressure may provide a form of psychophysiological relief under situations of stress and contribute to the development of essential hypertension in humans.
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Afferent and efferent connections of the A5 noradrenergic cell group in the rat.

TL;DR: In this article, the supraspinal afferent and efferent connections of the A5 noradrenergic cell group were examined in rats and very small deposits of HRP-WGA were made in the rostral A5 area.
References
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Inhibition of reflex bradycardia by stimulation of cerebral motor cortex.

TL;DR: Reports by Hoff and his colleagues confirm that electrical stimulation of the exposed cerebral cortex of the cat, dog and monkey 2 evokes cardiovascular responses and inhibiting or facilitating defence reactions 1° and that the baroreceptor reflexes are inhibited during stimulation in the hypothalamic areas which evoke defence reactions.
Journal Article

Behaviorally induced hypertension in the squirrel monkey.

TL;DR: Behaviorally induced hypertension in squirrel monkey following conditioned key-pressing response schedules is found to be related to stress-induced high blood pressure.
Journal ArticleDOI

Prolonged Pressor Effects of Selective Stimulation of the Stellate Ganglion

TL;DR: It is believed that neither cardiac acceleration nor systemic vasoconstriction contributed significantly to the pressor responses, but rather that augmentation of myocardial contraction and increased systolic ejection were the important causative factors.

Cardiovascular responses to avoidance conditioning in the dog: effects of alpha adrenergic blockade.

TL;DR: It is suggested that sustained cardiovascular responses during avoidance periods are associated with activation of the sympathetic nervous system, but that the gradual rise in blood pressure during pre-avoidance is due to other factors.
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