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Neurophysiology and neuropharmacology of cardiovascular regulation and stress

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TLDR
The conclusion is reached that further multidisciplinary research will reveal underlying neurophysiological and neuropharmacological mechanisms responsible for stress induced cardiovascular disease and lead to new methods of treatment.
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This article is published in Neuroscience & Biobehavioral Reviews.The article was published on 1981-03-01. It has received 121 citations till now.

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How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions.

TL;DR: This review considers recent findings regarding GC action and generates criteria for determining whether a particular GC action permits, stimulates, or suppresses an ongoing stress-response or, as an additional category, is preparative for a subsequent stressor.
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Autonomic determinism: the modes of autonomic control, the doctrine of autonomic space, and the laws of autonomic constraint.

TL;DR: A formal 2-dimensional conception of autonomic space is proposed, and a quantitative model for its translation into a functional output surface is derived and has fundamental implications for the direction and interpretation of a wide array of psychophysiological studies.
Journal ArticleDOI

Interactions Between Cardiovascular and Pain Regulatory Systems

TL;DR: The present analysis suggests that the inhibition of pain brought about by elevations in either arterial or venous blood pressure may provide a form of psychophysiological relief under situations of stress and contribute to the development of essential hypertension in humans.
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Afferent and efferent connections of the A5 noradrenergic cell group in the rat.

TL;DR: In this article, the supraspinal afferent and efferent connections of the A5 noradrenergic cell group were examined in rats and very small deposits of HRP-WGA were made in the rostral A5 area.
References
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Pontine and mesencephalic afferents to the central nucleus of the amygdala of the rat.

TL;DR: The pontine and mesencephalic afferent connections to the central nucleus of the amygdala have been studied by means of the retrograde transport of horseradish peroxidase by finding labeled neurons were consistently found in the dorsal raphe nucleus and the parabrachial nucleus.
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Cardiac dysrhythmias induced by autonomic nerve stimulation.

TL;DR: Neurally induced tachydysrhythmias resemble spontaneous arrhythmias in man, thus suggesting the possibility that arrh rhythmias in the human subject may be of autonomic nervous origin.
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Effects on heart rate of electrical stimulation of medullary vagal structures in the cat.

TL;DR: A successful demonstration of evoked potentials during induced bradycardia would allow determination of the range of conduction velocity in cardiomotor fibres, a parameter of identification for which there are now conflicting values.
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