Journal ArticleDOI
Phytosterols, phytostanols, and their conjugates in foods: structural diversity, quantitative analysis, and health-promoting uses
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TLDR
Phytosterols and phytostanols have received much attention in the last five years because of their cholesterol-lowering properties and the popularity of these products has caused the medical and biochemical community to focus much attention on phytosterol research activity.About:
This article is published in Progress in Lipid Research.The article was published on 2002-11-01. It has received 1014 citations till now. The article focuses on the topics: Phytosterol & Sterol.read more
Citations
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Sitostanetriol is not formed in vivo from sitosterol in the rat.
TL;DR: The results show that sitostanetriol and campestanetRIol were not formed in vivo from phytosterols, and it seems that the sitosta-like compound is eliminated very slowly from the organism.
Journal ArticleDOI
Optimization of Enzymatic Synthesis of Phytosteryl Caprylates Using Response Surface Methodology
Zhuliang Tan,Fereidoon Shahidi +1 more
TL;DR: In this article, the optimization of enzymatic synthesis of phytosteryl caprylates using response surface methodology (RSM) was investigated, the optimization process used a face-centred central composite design (CCD) and under optimized conditions (925 h, 215 substrate mole ratio, and 793% enzyme load) the resultant conversion yield was 98%
Journal ArticleDOI
Analysis of sitosteryl oleate esters in phytosterols esters enriched foods by HPLC–ESI-MS2
Diane Julien-David,Minjie Zhao,Philippe Geoffroy,Michel Miesch,Francis Raul,Dalal Aoude-Werner,Saïd Ennahar,Eric Marchioni +7 more
TL;DR: A high-speed HPLC-MS(2) method was developed to analyze the major PE present in PE-enriched spreads: sitosteryl oleate (SO) and its oxidation products, by using synthesized compounds as standards, and found that under specific heating conditions the decrease of the SO amount was much more important compared to the formation of SO oxides.
Journal ArticleDOI
Modulatory Effect of an Isolated Triglyceride from Fenugreek Seed Oil on of α-Amylase, Lipase and ACE Activities, Liver-Kidney Functions and Metabolic Disorders of Diabetic Rats.
TL;DR: It is demonstrated that administration of pure fenugreek TG to diabetic rats ameliorated the glycogen rate in liver and muscle and inhibited lipase activity in small intestine which leads to the regulation of lipid profile.
Journal ArticleDOI
Evaluation of Phytosterols in Milk and Yogurts Used as Functional Foods in Portugal
David Saraiva,Maria Conceição Castilho,Maria Rosário Martins,Maria Irene Noronha da Silveira,Fernando Ramos +4 more
TL;DR: It is demonstrated that the ingestion of phytosterols-enriched milk and yogurts could reduce cholesterolemia, and contrarily to milk, the different yogurt manufacturers had different options in the phydosterols added to the dairy foods commercialized.
References
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A rapid method of total lipid extraction and purification.
E. G. Bligh,W. J. Dyer +1 more
TL;DR: The lipid decomposition studies in frozen fish have led to the development of a simple and rapid method for the extraction and purification of lipids from biological materials that has been applied to fish muscle and may easily be adapted to use with other tissues.
Journal ArticleDOI
Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
Scott M. Grundy,David W. Bilheimer,Alan Chait,Luther T. Clark,Margo A. Denke,Richard J. Havel,William R. Hazzard,Stephen B. Hulley,Donald B. Hunninghake,Robert A. Kreisberg,Penny M. Kris-Etherton,James M. McKenney,Michael A. Newman,Ernst J. Schaefer,Burton E. Sobel,Carolyn Somelofski,Milton C. Weinstein,H. Bryan Brewer,James I. Cleeman,Karen A. Donato,Nancy D. Ernst,Jeffrey M. Hoeg,Basil M. Rifkind,Jacques E. Rossouw,Christopher T. Sempos,Joanne M. Gallivan,Maureen N. Harris,Laurie Quint-Adler +27 more
TL;DR: Dairy therapy remains the first line of treatment of high blood cholesterol, and drug therapy is reserved for patients who are considered to be at high risk for CHD, and the fundamental approach to treatment is comparable.
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Comprehensive insect physiology, biochemistry, and pharmacology
G. A. Kerkut,L. I. Gilbert +1 more
Journal ArticleDOI
Accumulation of Dietary Cholesterol in Sitosterolemia Caused by Mutations in Adjacent ABC Transporters
Knut Erik Berge,Hui Tian,Gregory A. Graf,Liqing Yu,Nick V. Grishin,Joshua Schultz,Peter Kwiterovich,Bei Shan,Robert Barnes,Helen H. Hobbs +9 more
TL;DR: Data suggest that ABCG5 and ABCG8 normally cooperate to limit intestinal absorption and to promote biliary excretion of sterols, and that mutated forms of these transporters predispose to sterol accumulation and atherosclerosis.