Journal ArticleDOI
SERS microscopy: nanoparticle probes and biomedical applications.
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TLDR
This review summarizes current designs of nanoparticle-based SERS probes and highlights first biomedical applications of SERS microscopy for protein localization ex and in vivo.Abstract:
Surface-enhanced Raman scattering (SERS) microscopy is a novel method of vibrational microspectroscopic imaging for the selective detection of biomolecules in targeted research This technique combines the advantages of biofunctionalized metal nanoparticles and Raman microspectroscopy for visualizing and quantifying the distribution of target molecules such as proteins in cells and tissues Advantages of SERS over existing labeling approaches include the tremendous multiplexing capacity, quantification using the characteristic SERS signatures and high photostability This review summarizes current designs of nanoparticle-based SERS probes and highlights first biomedical applications of SERS microscopy for protein localization ex and in vivoread more
Citations
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Journal ArticleDOI
Surface-enhanced Raman spectroscopy: concepts and chemical applications.
TL;DR: Chemical applications of SERS cover a broad range of topics such as catalysis and spectroelectrochemistry, single-molecule detection, and (bio)analytical chemistry.
Journal ArticleDOI
Present and Future of Surface-Enhanced Raman Scattering
Judith Langer,Dorleta Jimenez de Aberasturi,Javier Aizpurua,Ramon A. Alvarez-Puebla,Baptiste Auguié,Baptiste Auguié,Jeremy J. Baumberg,Guillermo C. Bazan,Steven E. J. Bell,Anja Boisen,Alexandre G. Brolo,Jaebum Choo,Dana Cialla-May,Dana Cialla-May,Volker Deckert,Volker Deckert,Laura Fabris,Karen Faulds,F. Javier García de Abajo,Royston Goodacre,Duncan Graham,Amanda J. Haes,Christy L. Haynes,Christian W. Huck,Tamitake Itoh,Mikael Käll,Janina Kneipp,Nicholas A. Kotov,Hua Kuang,Eric C. Le Ru,Eric C. Le Ru,Hiang Kwee Lee,Jian-Feng Li,Xing Yi Ling,Stefan A. Maier,Thomas G. Mayerhöfer,Thomas G. Mayerhöfer,Martin Moskovits,Kei Murakoshi,Jwa-Min Nam,Shuming Nie,Yukihiro Ozaki,Isabel Pastoriza-Santos,Jorge Pérez-Juste,Juergen Popp,Juergen Popp,Annemarie Pucci,Stephanie Reich,Bin Ren,George C. Schatz,Timur Shegai,Sebastian Schlücker,Li-Lin Tay,K. George Thomas,Zhong-Qun Tian,Richard P. Van Duyne,Tuan Vo-Dinh,Yue Wang,Katherine A. Willets,Chuanlai Xu,Hongxing Xu,Yikai Xu,Yuko S. Yamamoto,Bing Zhao,Luis M. Liz-Marzán +64 more
TL;DR: Prominent authors from all over the world joined efforts to summarize the current state-of-the-art in understanding and using SERS, as well as to propose what can be expected in the near future, in terms of research, applications, and technological development.
Journal ArticleDOI
SERS Tags: Novel Optical Nanoprobes for Bioanalysis
TL;DR: The fundamental theory of Surface-Enhanced Raman Scattering and the development of Multifunctional Nanoplatforms, a next generation of SERS tags, are studied.
Journal ArticleDOI
Localized surface plasmon resonance: nanostructures, bioassays and biosensing--a review.
TL;DR: This review serves to describe the physical theory of LSPR formation at the surface of nanostructures, and the potential for this optical technology to serve as a basis for the development bioassays and biosensing of high sensitivity.
Journal ArticleDOI
Highly uniform and reproducible surface-enhanced Raman scattering from DNA-tailorable nanoparticles with 1-nm interior gap
TL;DR: It is shown that DNA on gold nanoparticles facilitates the formation of well-defined gold nanobridged nanogap particles (Au-NNP) that generate a highly stable and reproducible SERS signal.
References
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