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Bruce M. Spiegelman
Researcher at Harvard University
Publications - 443
Citations - 172265
Bruce M. Spiegelman is an academic researcher from Harvard University. The author has contributed to research in topics: Adipose tissue & Transcription factor. The author has an hindex of 179, co-authored 434 publications receiving 158009 citations. Previous affiliations of Bruce M. Spiegelman include University of California, San Francisco & Vassar College.
Papers
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Vasodilation of rat retinal microvessels induced by monobutyrin. Dysregulation in diabetes.
Y.-D. C. Halvorsen,S E Bursell,W. O. Wilkison,Allen C. Clermont,M Brittis,T. J. Mcgovern,Bruce M. Spiegelman +6 more
TL;DR: A role for monobutyrin is demonstrated in the control of vascular tone and a possible involvement in the pathology of diabetes is suggested.
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The molecular link between obesity and diabetes
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Erratum: Increased muscle pgc-1αexpression protects from sarcopenia and metabolic disease during aging (Proceedings of the National Academy of Sciences of the United States of America (2009) 106 (20405-20410))
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Biosynthesis of the vasoactive lipid monobutyrin : central role of diacylglycerol
TL;DR: It is shown that diacylglycerol, an intermediate in the lipolytic pathway, can stimulate monobutyrin synthesis from an adipocyte particulate fraction and does so by acting as a substrate.
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Do Adipocytes Emerge from Mural Progenitors
TL;DR: Recent work, including their own, that suggested based on lineage tracing that mural cells are adipogenic, contrasting with the conclusions of a recent Cell Stem Cell paper are highlighted.