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Claude Bouchard
Researcher at Pennington Biomedical Research Center
Publications - 1105
Citations - 121841
Claude Bouchard is an academic researcher from Pennington Biomedical Research Center. The author has contributed to research in topics: Body mass index & Obesity. The author has an hindex of 153, co-authored 1076 publications receiving 115307 citations. Previous affiliations of Claude Bouchard include Texas A&M University & University of Texas at Austin.
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Journal ArticleDOI
Severe obesity is associated with novel single nucleotide polymorphisms of the ESR1 and PPARγ locus in Han Chinese
TL;DR: Severe obesity in Han Chinese was associated with 3 novel common SNPs for ESR1 and PPARgamma, which collectively result in a >5-fold risk of severe obesity.
Journal ArticleDOI
Functional identification of the promoter of SLC4A5 , a gene associated with cardiovascular and metabolic phenotypes in the HERITAGE Family Study
TL;DR: The observed associations with resting and submaximal-exercise cardiovascular and metabolic traits in the HERITAGE Family Study are likely due to neither variation in the promoter nor known coding SNPs of SLC4A5.
Journal ArticleDOI
Variations in the four and a half LIM domains 1 gene (FHL1) are associated with fasting insulin and insulin sensitivity responses to regular exercise
Margarita Teran-Garcia,Tuomo Rankinen,Treva Rice,Arthur S. Leon,D. C. Rao,James S. Skinner,Claude Bouchard +6 more
TL;DR: Fasting insulin and SI responses to exercise training were associated with DNA sequence variation in FHL1 inwhite men, and whether these associations exist only in white men remains to be investigated.
Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions
Paul S. de Vries,Michael R. Brown,Amy R. Bentley,Yun J. Sung,Thomas W. Winkler,Ioanna Ntalla,Karen Schwander,Aldi T. Kraja,Xiuqing Guo,Nora Franceschini,Ching-Yu Cheng,Xueling Sim,Dina Vojinovic,Jennifer E. Huffman,Solomon K. Musani,Changwei Li,Mary F. Feitosa,Melissa A. Richard,Raymond Noordam,Hugues Aschard,Traci M. Bartz,Lawrence F. Bielak,Xuan Deng,Rajkumar Dorajoo,Kurt Lohman,Alisa K. Manning,Tuomo Rankinen,Albert V. Smith,Salman M. Tajuddin,Evangelos Evangelou,Mariaelisa Graff,Maris Alver,Mathilde Boissel,Jin-Fang Chai,Xu Chen,Jasmin Divers,Ilaria Gandin,Chuan Gao,Anuj Goel,Yanick Hagemeijer,Sarah E. Harris,Fernando Pires Hartwig,Meian He,Andrea R. V. R. Horimoto,Fang-Chi Hsu,Anne U. Jackson,Anuradhani Kasturiratne,Pirjo Komulainen,Brigitte Kuehnel,Federica Laguzzi,Joseph H. Lee,Jian'an Luan,Leo-Pekka Lyytikäinen,Nana Matoba,Ilja M. Nolte,Maik Pietzner,Muhammad Riaz,M. Abdullah Said,Robert A. Scott,Tamar Sofer,Alena Stančáková,Fumihiko Takeuchi,Bamidele O. Tayo,Peter J. van der Most,Tibor V. Varga,Yajuan Wang,Erin B. Ware,Wanqing Wen,Lisa R. Yanek,Weihua Zhang,Jing Hua Zhao,Saima Afaq,Najaf Amin,Marzyeh Amini,Dan E. Arking,Tin Aung,Christie M. Ballantyne,Eric Boerwinkle,Ulrich Broeckel,Archie Campbell,Mickaël Canouil,Sabanayagam Charumathi,Yii-Der Ida Chen,John M. C. Connell,Ulf de Faire,Lisa de las Fuentes,Renée de Mutsert,H. Janaka de Silva,Jingzhong Ding,Anna F. Dominiczak,Qing Duan,Charles B. Eaton,Ruben N. Eppinga,Jessica D. Faul,Virginia Fisher,Terrence Forrester,Oscar H. Franco,Yechiel Friedlander,Mohsen Ghanbari,Franco Giulianini,Hans J. Grabe,Megan L. Grove,C. Charles Gu,Tamara B. Harris,Sami Heikkinen,Chew-Kiat Heng,Makoto Hirata,James E. Hixson,Barbara V. Howard,M. Arfan Ikram,David R. Jacobs,Craig Johnson,Jost B. Jonas,Candace M. Kammerer,Tomohiro Katsuya,Chiea Chuen Khor,Tuomas O. Kilpeläinen,Woon-Puay Koh,Heikki A. Koistinen,Ivana Kolcic,Charles Kooperberg,José Eduardo Krieger,Steve B. Kritchevsky,Michiaki Kubo,Johanna Kuusisto,Timo A. Lakka,Carl D. Langefeld,Claudia Langenberg,Lenore J. Launer,Benjamin Lehne,Rozenn N. Lemaitre,Yize Li,Jingjing Liang,Jianjun Liu,Kiang Liu,Marie Loh,Tin Louie,Reedik Mägi,Ani Manichaikul,Colin A. McKenzie,Thomas Meitinger,Andres Metspalu,Yuri Milaneschi,Lili Milani,Karen L. Mohlke,Thomas H. Mosley,Kenneth J. Mukamal,Mike A. Nalls,Matthias Nauck,Christopher P. Nelson,Nona Sotoodehnia,Jeffrey R. O'Connell,Nicholette D. Palmer,Raha Pazoki,Nancy L. Pedersen,Annette Peters,Patricia A. Peyser,Ozren Polasek,Neil R Poulter,Leslie J. Raffel,Olli T. Raitakari,Alexander P. Reiner,Treva Rice,Stephen S. Rich,Antonietta Robino,Jennifer G. Robinson,Lynda M. Rose,Igor Rudan,Carsten Oliver Schmidt,Pamela J. Schreiner,William R. Scott,Peter S. Sever,Yuan Shi,Stephen Sidney,Mario Sims,Blair H. Smith,Jennifer A. Smith,Harold Snieder,John M. Starr,Konstantin Strauch,Nicholas Y. Q. Tan,Kent D. Taylor,Yik Ying Teo,Yih Chung Tham,André G. Uitterlinden,Diana van Heemst,Dragana Vuckovic,Melanie Waldenberger,Lihua Wang,Yujie Wang,Zhe Wang,Wen Bin Wei,Christine Williams,Gregory P. Wilson,Mary K. Wojczynski,Jie Yao,Bing Yu,Caizheng Yu,Jian-Min Yuan,Wei Zhao,Alan B. Zonderman,Diane M. Becker,Michael Boehnke,Donald W. Bowden,John C. Chambers,Ian J. Deary,Tõnu Esko,Martin Farrall,Paul W. Franks,Barry I. Freedman,Philippe Froguel,Paolo Gasparini,Christian Gieger,Bernardo L. Horta,Yoichiro Kamatani,Norihiro Kato,Jaspal S. Kooner,Markku Laakso,Karin Leander,Terho Lehtimäki,Patrik K. E. Magnusson,Brenda W.J.H. Penninx,Alexandre C. Pereira,Rainer Rauramaa,Nilesh J. Samani,James F. Scott,Xiao-Ou Shu,Pim van der Harst,Lynne E. Wagenknecht,Ya Xing Wang,Nicholas J. Wareham,Hugh Watkins,David R. Weir,Ananda R. Wickremasinghe,Wei Zheng,Paul Elliott,Kari E. North,Claude Bouchard,Michele K. Evans,Vilmundur Gudnason,Ching-Ti Liu,Yongmei Liu,Bruce M. Psaty,Paul M. Ridker,Rob M. van Dam,Sharon L.R. Kardia,Xiaofeng Zhu,Charles N. Rotimi,Dennis O. Mook-Kanamori,Myriam Fornage,Tanika N. Kelly,Ervin R. Fox,Caroline Hayward,Cornelia M. van Duijn,E. Shyong Tai,Tien Yin Wong,Jingmin Liu,Jerome I. Rotter,W. James Gauderman,Michael A. Province,Patricia B. Munroe,Kenneth Rice,Daniel I. Chasman,L. Adrienne Cupples,Dabeeru C. Rao,Alanna C. Morrison +265 more
TL;DR: A person's lipid profile is influenced by genetic variants and alcohol consumption, but the contribution of interactions between these exposures has not been studied, so gene-alcohol interactions are incorporated into a multiancestry genome-wide association study of levels of high-density lipoprotein cholesterol, low-density cholesterol, and triglycerides.
Journal ArticleDOI
Predictors of body composition and body energy changes in response to chronic overfeeding
TL;DR: Although none of the variables exerted individually an overwhelmingly strong influence on overfeeding-induced changes, baseline FFM, maximal oxygen uptake, muscle oxidative capacity, androgens and leptin levels were the most consistent significant biomarkers of the responsiveness to chronic overfeeding.