Lisa de las Fuentes

TL;DR: In insights into the role of alcohol consumption in the genetic architecture of hypertension, a large two-stage investigation incorporating joint testing of main genetic effects and single nucleotide variant (SNV)-alcohol consumption interactions is conducted.

TL;DR: It is demonstrated that moderate 5% weight loss improves metabolic function in multiple organs simultaneously, and progressive weight loss causes dose-dependent alterations in key adipose tissue biological pathways.

TL;DR: Patients with idiopathic dilated cardiomyopathy exhibit alterations in myocardial metabolism characterized by decreased fatty acid metabolism and increased myocardian glucose metabolism, a pattern similar to that shown in animal models of HF.

TL;DR: Patients with metabolic syndrome have LV diastolic dysfunction independent of LV mass, which may partially explain the increased cardiovascular morbidity and mortality associated with metabolic Syndrome.

TL;DR: Left ventricular mass showed significant correlation with gender, diastolic and systolic blood pressure, myocardial fatty acid uptake, utilization and oxidation, myCardial blood flow, body mass index, and left ventricular ejection fraction, and myocardian fatty acid metabolism is an independent predictor of left Ventricular mass in hypertension and inleft ventricular dysfunction.