D
David Reich
Researcher at Icahn School of Medicine at Mount Sinai
Publications - 695
Citations - 107008
David Reich is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Population & Ancient DNA. The author has an hindex of 137, co-authored 644 publications receiving 91397 citations. Previous affiliations of David Reich include Mount Sinai St. Luke's and Mount Sinai Roosevelt & Howard Hughes Medical Institute.
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Journal ArticleDOI
Genetic markers for ancestry are correlated with body composition traits in older African Americans.
John R. Shaffer,Candace M. Kammerer,David Reich,David Reich,Gavin J. McDonald,Gavin J. McDonald,Nick Patterson,Bret H. Goodpaster,Douglas C. Bauer,Jian-Mei Li,A.B. Newman,J. A. Cauley,Tamara B. Harris,F. Tylavsky,Robert E. Ferrell,Joseph M. Zmuda +15 more
TL;DR: Findings indicate that some population differences in body composition may be due to population-specific allele frequencies, suggesting the utility of admixture mapping for identifying susceptibility genes for osteoporosis, sarcopenia, and obesity.
Journal ArticleDOI
Results from a prostate cancer admixture mapping study in African-American men
Cathryn H. Bock,Ann G. Schwartz,Julie J. Ruterbusch,Albert M. Levin,Christine Neslund-Dudas,Susan Land,Angela S. Wenzlaff,David Reich,David Reich,Paul M. McKeigue,Wei Chen,Elisabeth I. Heath,Isaac J. Powell,Rick A. Kittles,Benjamin A. Rybicki +14 more
TL;DR: Admirixture mapping in AA men from two independent case–control studies of prostate cancer is performed to confirm the 8q24 ancestry association and also identify other genomic regions that may harbor prostate cancer susceptibility genes.
Journal ArticleDOI
A Working Model of the Deep Relationships of Diverse Modern Human Genetic Lineages Outside of Africa.
TL;DR: A model that provides a good statistical fit to allele-frequency correlation patterns among East Asians, Australasians, Native Americans, and ancient western and northern Eurasians, together with archaic human groups is reported, providing a useful summary of deep Eurasian population history.
Posted ContentDOI
The Genomic Formation of South and Central Asia
Vagheesh M. Narasimhan,Nick Patterson,Nick Patterson,Priya Moorjani,Iosif Lazaridis,Mark Lipson,Swapan Mallick,Swapan Mallick,Nadin Rohland,Rebecca Bernardos,Alexander M. Kim,Nathan Nakatsuka,Iñigo Olalde,Alfredo Coppa,James Mallory,Vyacheslav Moiseyev,Janet Monge,Luca M. Olivieri,Nicole Adamski,Nasreen Broomandkhoshbacht,Francesca Candilio,Olivia Cheronet,Olivia Cheronet,Brendan J. Culleton,Matthew Ferry,Daniel Fernandes,Beatriz Gamarra,Daniel Gaudio,Mateja Hajdinjak,Eadaoin Harney,Thomas K. Harper,Denise Keating,Ann Marie Lawson,Megan Michel,Mario Novak,Jonas Oppenheimer,Niraj Rai,Niraj Rai,Kendra Sirak,Kendra Sirak,Kendra Sirak,Viviane Slon,Kristin Stewardson,Zhao Zhang,Gaziz Akhatov,Anatoly N. Bagashev,Bauryzhan Baitanayev,Gian Luca Bonora,T. A. Chikisheva,Anatoly P. Derevianko,Dmitry Enshin,Katerina Douka,Katerina Douka,Nadezhda Dubova,Andrey Epimakhov,Suzanne Freilich,Dorian Q. Fuller,Dorian Q. Fuller,Alexander Goryachev,Andrey Gromov,Bryan Hanks,Margaret A. Judd,Erlan Kazizov,Aleksander Khokhlov,Egor Kitov,Egor Kitov,Elena Kupriyanova,Pavel Kuznetsov,Donata Luiselli,Farhod Maksudov,Christopher Meiklejohn,Deborah C. Merrett,Roberto Micheli,Oleg Mochalov,Muhammad Zahir,Muhammad Zahir,Samariddin Mustafokulov,Ayushi Nayak,Marina Petrovna Rykun,Davide Pettener,Richard Potts,Dmitry Razhev,Stefania Sarno,Kulyan Sikhymbaeva,Sergey Mikhailovich Slepchenko,Nadezhda Stepanova,Svetlana V. Svyatko,Svetlana V. Svyatko,Sergey Vasilyev,Massimo Vidale,Dmitriy Voyakin,Antonina Yermolayeva,A. V. Zubova,Vasant Shinde,Carles Lalueza-Fox,Matthias Meyer,David W. Anthony,Nicole Boivin,Kumarasamy Thangaraj,Douglas J. Kennett,Douglas J. Kennett,Michael D. Frachetti,Ron Pinhasi,Ron Pinhasi,David Reich +104 more
TL;DR: The results show how ancestry from the Steppe genetically linked Europe and South Asia in the Bronze Age, and identifies the populations that almost certainly were responsible for spreading Indo-European languages across much of Eurasia.
Journal ArticleDOI
Single-nucleotide polymorphisms in LPA explain most of the ancestry-specific variation in Lp(a) levels in African Americans.
Rahul C. Deo,James G. Wilson,Chao Xing,Kim Lawson,W. H. Linda Kao,David Reich,David Reich,Arti Tandon,Ermeg L. Akylbekova,Ermeg L. Akylbekova,Nick Patterson,Nick Patterson,Thomas H. Mosley,Eric Boerwinkle,Herman A. Taylor,Herman A. Taylor,Herman A. Taylor +16 more
TL;DR: Despite the strong association with Lp(a) levels, the genetic basis of this association is investigated using a panel of up to 1447 ancestry informative markers, and no association of any LPA SNP with incident coronary heart disease is found.