David W. Johnson

TL;DR: A hydride cold-trapping technique was developed and optimised for the measurement of urinary arsenic metabolites and up to two fold increases of urinary ASi excretion in rats compared with control rats were also observed in animals dosed with various forms of arsenicals.

TL;DR: This is the first report showing that miRNAs can be built into molecular diagnostic strategies for risk stratification in MM, and an “outcome classifier”, based on the expression of two mi RNAs, which is able to stratify patients into three risk groups.

TL;DR: Evidence comparing the safety profiles of three groups of oral medications, acetaminophen, nonsteroidal anti-inflammatory drugs, and opioids, to manage acute nonsurgical pain in children treated in ambulatory settings highlights challenges in assessing medication safety, including lack of more detailed information in registry data, and inconsistent reporting in trials.

TL;DR: In patients with stage 3b/4 CKD, treatment with lanthanum over 96 weeks did not affect arterial stiffness or aortic calcification compared with placebo, and the role of intestinal phosphate binders to reduce cardiovascular risk in patients with CKD who have normophosphatemia is not supported.

TL;DR: The data presented indicate that the oxidation of alpha- and gamma-methyl isoprenoid-derived fatty acids takes place largely in peroxisomes in human skin fibroblasts.