D
David W. Johnson
Researcher at University of Queensland
Publications - 2880
Citations - 157072
David W. Johnson is an academic researcher from University of Queensland. The author has contributed to research in topics: Peritoneal dialysis & Kidney disease. The author has an hindex of 160, co-authored 2714 publications receiving 140778 citations. Previous affiliations of David W. Johnson include Minnesota Department of Transportation & Open University.
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Journal ArticleDOI
The effectiveness of glucocorticoids in treating croup: meta-analysis.
Monica Ausejo,Antonio Saenz,Ba' Pham,James D. Kellner,David W. Johnson,David Moher,Terry P. Klassen +6 more
TL;DR: A meta-analysis of randomized controlled trials that examined the effectiveness of glucocorticoid treatment in children with croup was carried out in this paper, with an effect size of −1.0 (−1.6 to −0.4) and at 24 hours this improvement was no longer significant, and for inpatients hospital stay was reduced by 16 hours (−31 to 1 hour).
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Reduced dosage of ERF causes complex craniosynostosis in humans and mice and links ERK1/2 signaling to regulation of osteogenesis
Stephen R.F. Twigg,Elena Vorgia,Elena Vorgia,Simon J. McGowan,Ioanna Peraki,Ioanna Peraki,Aimee L. Fenwick,Vikram P Sharma,Maryline Allegra,Andreas Zaragkoulias,Elham Sadighi Akha,Samantha J. L. Knight,Helen Lord,Tracy Lester,Louise Izatt,Anne K. Lampe,Shehla Mohammed,Fiona Stewart,Alain Verloes,Louise C. Wilson,Chris Healy,Paul T. Sharpe,Peter Hammond,Jim R. Hughes,Stephen S. Taylor,David W. Johnson,Steven A. Wall,George Mavrothalassitis,George Mavrothalassitis,Andrew O.M. Wilkie +29 more
TL;DR: Reduced dosage of ERF, which encodes an inhibitory ETS transcription factor directly bound by ERK1/2, causes complex craniosynostosis in humans and mice and is identified as a novel regulator of osteogenic stimulation by RAS-ERK signaling, potentially by competing with activating ETS factors in multifactor transcriptional complexes.
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The complete sequence of a heterochromatic island from a higher eukaryote
W. R. McCombie,M. de la Bastide,K. Habermann,L. Parnell,Neilay Dedhia,L. Gnoj,K. Schutz,E. Huang,Lori Spiegel,C. Yordan,M. Sehkon,Joseph A. Murray,P. Sheet,Matt Cordes,J. Threideh,T. Stoneking,Joelle Kalicki,Tina Graves,G. Harmon,Jennifer Edwards,P. Latreille,Laura Courtney,J. Cloud,A. Abbott,Kelsi Scott,David W. Johnson +25 more
TL;DR: The complete sequence of a heterochromatic island of Arabidopsis thaliana chromosome 4 provides an opportunity to study sequence determinants of chromosome condensation.
Journal ArticleDOI
Is obesity a favorable prognostic factor in peritoneal dialysis patients
David W. Johnson,Karen A. Herzig,David M. Purdie,Wendy Chang,Allison M. Brown,Russell J. Rigby,Scott B. Campbell,David Nicol,Carmel M. Hawley +8 more
TL;DR: Obese patients should not be discouraged from receiving peritoneal dialysis purely on the basis of BMI, and maintaining a higher-than-average BMI to preserve “nutritional reserve” may help to reduce the mortality and morbidity rates associated with PD.
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Paracrine stimulation of human renal fibroblasts by proximal tubule cells.
TL;DR: PTC modulate the biological behavior of neighboring cortical fibroblasts in the human kidney through paracrine mechanisms, which include the production and release of PDGF-AB and TGF-beta1 and T GF- beta1, which culminates in excessive fibroblast proliferation and interstitial fibrosis.