F
Francesc Balaguer
Researcher at University of Barcelona
Publications - 241
Citations - 8187
Francesc Balaguer is an academic researcher from University of Barcelona. The author has contributed to research in topics: Colorectal cancer & Cancer. The author has an hindex of 42, co-authored 194 publications receiving 6594 citations. Previous affiliations of Francesc Balaguer include Baylor University & Baylor University Medical Center.
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Journal ArticleDOI
MicroRNA-200c modulates epithelial-to-mesenchymal transition (EMT) in human colorectal cancer metastasis
Keun Hur,Yuji Toiyama,Masanobu Takahashi,Francesc Balaguer,Takeshi Nagasaka,Junichi Koike,Hiromichi Hemmi,Minoru Koi,C. Richard Boland,Ajay Goel +9 more
TL;DR: The role of miR-200 members in the pathogenesis of metastatic colorectal cancer has not been investigated as mentioned in this paper, although the miR200 family is a crucial inhibitor of epithelial-to-mesenchymal transition (EMT) in human cancer.
Journal ArticleDOI
Identification of Lynch syndrome among patients with colorectal cancer
Leticia Moreira,Francesc Balaguer,Noralane M. Lindor,Albert de la Chapelle,Heather Hampel,Lauri A. Aaltonen,John L. Hopper,Loic Le Marchand,Steven Gallinger,Polly A. Newcomb,Robert W. Haile,Stephen N. Thibodeau,Shanaka R. Gunawardena,Mark A. Jenkins,Daniel D. Buchanan,John D. Potter,John A. Baron,Dennis J. Ahnen,Victor Moreno,Montserrat Andreu,Maurizio Ponz de Leon,Anil K. Rustgi,Antoni Castells +22 more
TL;DR: Universal tumor MMR testing among CRC probands had a greater sensitivity for the identification of Lynch syndrome compared with multiple alternative strategies, although the increase in the diagnostic yield was modest.
Journal ArticleDOI
Cancer chemoprevention by dietary polyphenols: promising role for epigenetics.
TL;DR: It is emphasized how increased understanding of the chemopreventive effects of dietary polyphenols on specific epigenetic alterations may provide unique and yet unexplored novel and highly effective chemopresventive strategies for reducing the health burden of cancer and other diseases in humans.
Journal ArticleDOI
Epigenetics of colorectal cancer: biomarker and therapeutic potential.
TL;DR: This Review outlines these epigenetic aberrations in CRC and their potential as diagnostic, prognostic and predictive biomarkers and therapeutic targets, as well as the role of non-coding RNAs as epigenetic regulators.
Journal ArticleDOI
Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database
Mev Dominguez-Valentin,Julian R. Sampson,Toni T. Seppälä,Sanne W. ten Broeke,John-Paul Plazzer,Sigve Nakken,Christoph Engel,Stefan Aretz,Mark A. Jenkins,Lone Sunde,Lone Sunde,Inge Bernstein,Gabriel Capellá,Francesc Balaguer,Huw D. Thomas,D. Gareth Evans,D. Gareth Evans,John Burn,Marc S. Greenblatt,Eivind Hovig,Wouter H. de Vos tot Nederveen Cappel,Rolf H. Sijmons,Lucio Bertario,Maria Grazia Tibiletti,Giulia Martina Cavestro,Annika Lindblom,Adriana Della Valle,Francisco López-Köstner,Nathan Gluck,Lior H. Katz,Karl Heinimann,Carlos A. Vaccaro,Reinhard Büttner,Heike Görgens,Elke Holinski-Feder,Monika Morak,Stefanie Holzapfel,Robert Hüneburg,Magnus von Knebel Doeberitz,Magnus von Knebel Doeberitz,Markus Loeffler,Nils Rahner,Hans K. Schackert,Verena Steinke-Lange,Wolff Schmiegel,Deepak Vangala,Kirsi Pylvänäinen,Laura Renkonen-Sinisalo,Laura Renkonen-Sinisalo,John L. Hopper,Aung Ko Win,Robert W. Haile,Noralane M. Lindor,Steven Gallinger,Loic Le Marchand,Polly A. Newcomb,Jane C. Figueiredo,Stephen N. Thibodeau,Karin Wadt,Christina Therkildsen,Henrik Okkels,Zohreh Ketabi,Leticia Moreira,Ariadna Sánchez,Miquel Serra-Burriel,Marta Pineda,Matilde Navarro,Ignacio Blanco,Kate Green,Fiona Lalloo,Emma J Crosbie,James Hill,Oliver G. Denton,Ian M. Frayling,Einar Andreas Rødland,Hans F. A. Vasen,Miriam Mints,Florencia Neffa,Patricia Esperon,Karin Alvarez,Revital Kariv,Guy Rosner,Tamara Alejandra Piñero,María Laura Gonzalez,Pablo Kalfayan,Douglas Tjandra,Ingrid Winship,Ingrid Winship,Finlay A. Macrae,Finlay A. Macrae,Gabriela Möslein,Jukka-Pekka Mecklin,Maartje Nielsen,Pål Møller,Pål Møller +94 more
TL;DR: Management guidelines for Lynch syndrome may require revision in light of these different gene and gender-specific risks and the good prognosis for the most commonly associated cancers.