H
Han Sang Kim
Researcher at Yonsei University
Publications - 75
Citations - 4064
Han Sang Kim is an academic researcher from Yonsei University. The author has contributed to research in topics: Medicine & Cancer. The author has an hindex of 18, co-authored 56 publications receiving 2477 citations. Previous affiliations of Han Sang Kim include University Health System & Merck & Co..
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Journal ArticleDOI
Extracellular Vesicles in Cancer: Cell-to-Cell Mediators of Metastasis
Annette Becker,Basant Kumar Thakur,Joshua Mitchell Weiss,Han Sang Kim,Han Sang Kim,Héctor Peinado,David Lyden +6 more
TL;DR: Clinically, EVs may be biomarkers and novel therapeutic targets for cancer progression, particularly for predicting and preventing future metastatic development.
Journal ArticleDOI
Identification of distinct nanoparticles and subsets of extracellular vesicles by asymmetric flow field-flow fractionation.
Haiying Zhang,Daniela Freitas,Han Sang Kim,Han Sang Kim,Kristina I. Fabijanic,Zhong Li,Haiyan Chen,Haiyan Chen,Milica Tesic Mark,Henrik Molina,Alberto Benito Martin,Linda Bojmar,Justin Fang,Sham Rampersaud,Ayuko Hoshino,Irina Matei,Candia M. Kenific,Miho Nakajima,Anders P. Mutvei,Pasquale Sansone,Weston Buehring,Huajuan Wang,Juan Pablo Jimenez,Leona Cohen-Gould,Navid Paknejad,Matthew Brendel,Katia Manova-Todorova,Ana Magalhães,José Alexandre Ferreira,Hugo Osório,André M. N. Silva,Ashish Massey,Juan R. Cubillos-Ruiz,Giuseppe Galletti,Paraskevi Giannakakou,Ana Maria Cuervo,John Blenis,Robert E. Schwartz,Mary Sue Brady,Héctor Peinado,Jacqueline Bromberg,Jacqueline Bromberg,Hiroshi Matsui,Celso A. Reis,David Lyden,David Lyden +45 more
TL;DR: It is shown that AF4 can serve as an improved analytical tool for isolating extracellular vesicles and addressing the complexities of heterogeneous nanoparticle subpopulations, and three nanoparticle subsets demonstrated diverse organ biodistribution patterns, suggesting distinct biological functions.
Journal ArticleDOI
Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers
Ayuko Hoshino,Ayuko Hoshino,Han Sang Kim,Han Sang Kim,Linda Bojmar,Linda Bojmar,Linda Bojmar,Kofi Ennu Gyan,Michele Cioffi,Jonathan M. Hernandez,Jonathan M. Hernandez,Jonathan M. Hernandez,Constantinos P. Zambirinis,Constantinos P. Zambirinis,Gonçalo Rodrigues,Gonçalo Rodrigues,Henrik Molina,Søren Heissel,Milica Tesic Mark,Loïc Steiner,Loïc Steiner,Alberto Benito-Martin,Serena Lucotti,Angela Di Giannatale,Katharine Offer,Miho Nakajima,Caitlin Williams,Laura Nogués,Laura Nogués,Fanny A. Pelissier Vatter,Ayako Hashimoto,Ayako Hashimoto,Ayako Hashimoto,Alexander E. Davies,Daniela Freitas,Daniela Freitas,Candia M. Kenific,Yonathan Ararso,Weston Buehring,Pernille Lauritzen,Yusuke Ogitani,Kei Sugiura,Kei Sugiura,Naoko Takahashi,Maša Alečković,Kayleen A. Bailey,Joshua S. Jolissant,Joshua S. Jolissant,Huajuan Wang,Ashton Harris,L. Miles Schaeffer,Guillermo García-Santos,Guillermo García-Santos,Zoe Posner,Vinod P. Balachandran,Yasmin Khakoo,G. Praveen Raju,Avigdor Scherz,Irit Sagi,Ruth Scherz-Shouval,Yosef Yarden,Moshe Oren,Mahathi Malladi,Mary Petriccione,Kevin C. De Braganca,Maria Donzelli,Cheryl Fischer,Stephanie Vitolano,Geraldine P. Wright,Lee Ganshaw,Mariel Marrano,Amina Ahmed,Joe DeStefano,Enrico Danzer,Michael H.A. Roehrl,Norman J. Lacayo,Theresa C. Vincent,Theresa C. Vincent,Martin R. Weiser,Mary S. Brady,Paul A. Meyers,Leonard H. Wexler,Srikanth R. Ambati,Alexander J. Chou,Emily K. Slotkin,Shakeel Modak,Stephen S. Roberts,Ellen M. Basu,Daniel Diolaiti,Benjamin A. Krantz,Benjamin A. Krantz,Fatima Cardoso,Amber L. Simpson,Michael F. Berger,Charles M. Rudin,Diane M. Simeone,Maneesh Jain,Cyrus M. Ghajar,Surinder K. Batra,Ben Z. Stanger,Jack D. Bui,Kristy A. Brown,Vinagolu K. Rajasekhar,John H. Healey,Maria de Sousa,Maria de Sousa,Kim Kramer,Sujit Sheth,Jeanine Baisch,Virginia Pascual,Todd E. Heaton,Michael P. La Quaglia,David J. Pisapia,Robert E. Schwartz,Haiying Zhang,Yuan Liu,Arti Shukla,Laurence Blavier,Yves A. DeClerck,Mark A. LaBarge,Mina J. Bissell,Thomas C. Caffrey,Paul M. Grandgenett,Michael A. Hollingsworth,Jacqueline Bromberg,Jacqueline Bromberg,Bruno Costa-Silva,Héctor Peinado,Yibin Kang,Benjamin A. Garcia,Eileen M. O'Reilly,David P. Kelsen,Tanya M. Trippett,David R. Jones,Irina Matei,William R. Jarnagin,David Lyden +136 more
TL;DR: EVP proteins can serve as reliable biomarkers for cancer detection and determining cancer type, and a panel of tumor-type-specific EVP proteins in TEs and plasma are defined, which can classify tumors of unknown primary origin.
Journal ArticleDOI
Tumour exosomal CEMIP protein promotes cancer cell colonization in brain metastasis
Gonçalo Rodrigues,Gonçalo Rodrigues,Ayuko Hoshino,Ayuko Hoshino,Ayuko Hoshino,Candia M. Kenific,Irina Matei,Loïc Steiner,Loïc Steiner,Daniela Freitas,Han Sang Kim,Han Sang Kim,Peter R. Oxley,Ilana Scandariato,Irene Casanova-Salas,Jinxiang Dai,Chaitanya R. Badwe,Brunilde Gril,Milica Tesic Mark,Brian D. Dill,Henrik Molina,Haiying Zhang,Alberto Benito-Martin,Linda Bojmar,Yonathan Ararso,Katharine Offer,Quincey LaPlant,Weston Buehring,Huajuan Wang,Xinran Jiang,Tyler M. Lu,Yuan Liu,Joshua K. Sabari,Sandra J. Shin,Navneet Narula,Paula S. Ginter,Vinagolu K. Rajasekhar,John H. Healey,Etienne Meylan,Bruno Costa-Silva,Shizhen Emily Wang,Shahin Rafii,Nasser K. Altorki,Charles M. Rudin,David R. Jones,Patricia S. Steeg,Héctor Peinado,Cyrus M. Ghajar,Jacqueline Bromberg,Jacqueline Bromberg,Maria de Sousa,Maria de Sousa,David J. Pisapia,David Lyden +53 more
TL;DR: It is demonstrated that pre-conditioning the brain microenvironment with exosomes from brain metastatic cells enhances cancer cell outgrowth, and that targeting exosomal CEMIP could constitute a future avenue for the prevention and treatment of brain metastasis.
Journal ArticleDOI
Identification of a radiosensitivity signature using integrative metaanalysis of published microarray data for NCI-60 cancer cells
Han Sang Kim,Sang Cheol Kim,Sun Jeong Kim,Chan Hee Park,Hei Cheul Jeung,Yong Bae Kim,Joong Bae Ahn,Hyun Cheol Chung,Sun Young Rha +8 more
TL;DR: The results suggested that the identified genes are candidates for radiosensitivity biomarkers and that integrin signaling via adhesion molecules could be a target for radiosensitization.