L
Linda Bojmar
Researcher at Cornell University
Publications - 23
Citations - 5763
Linda Bojmar is an academic researcher from Cornell University. The author has contributed to research in topics: Cancer & Metastasis. The author has an hindex of 11, co-authored 17 publications receiving 3853 citations. Previous affiliations of Linda Bojmar include Uppsala University & Karolinska Institutet.
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Journal ArticleDOI
Tumour exosome integrins determine organotropic metastasis
Ayuko Hoshino,Bruno Costa-Silva,Tang-Long Shen,Gonçalo Rodrigues,Ayako Hashimoto,Milica Tesic Mark,Henrik Molina,Shinji Kohsaka,Angela Di Giannatale,Sophia Ceder,Swarnima Singh,Caitlin Williams,Nadine Soplop,Kunihiro Uryu,Lindsay A. Pharmer,Tari A. King,Linda Bojmar,Alexander E. Davies,Yonathan Ararso,Tuo Zhang,Haiying Zhang,Jonathan M. Hernandez,Joshua Mitchell Weiss,Vanessa D. Dumont-Cole,Kimberly Kramer,Leonard H. Wexler,Aru Narendran,Gary K. Schwartz,John H. Healey,Per Sandström,Knut Jørgen Labori,Elin H. Kure,Paul M. Grandgenett,Michael A. Hollingsworth,Maria de Sousa,Sukwinder Kaur,Maneesh Jain,Kavita Mallya,Surinder K. Batra,William R. Jarnagin,Mary S. Brady,Øystein Fodstad,Volkmar Müller,Klaus Pantel,Andy J. Minn,Mina J. Bissell,Benjamin A. Garcia,Yibin Kang,Yibin Kang,Vinagolu K. Rajasekhar,Cyrus M. Ghajar,Irina Matei,Héctor Peinado,Jacqueline Bromberg,Jacqueline Bromberg,David Lyden +55 more
TL;DR: It is demonstrated that exosomes from mouse and human lung-, liver- and brain-tropic tumour cells fuse preferentially with resident cells at their predicted destination, namely lung fibroblasts and epithelial cells, liver Kupffer cells and brain endothelial cells.
Journal ArticleDOI
Identification of distinct nanoparticles and subsets of extracellular vesicles by asymmetric flow field-flow fractionation.
Haiying Zhang,Daniela Freitas,Han Sang Kim,Han Sang Kim,Kristina I. Fabijanic,Zhong Li,Haiyan Chen,Haiyan Chen,Milica Tesic Mark,Henrik Molina,Alberto Benito Martin,Linda Bojmar,Justin Fang,Sham Rampersaud,Ayuko Hoshino,Irina Matei,Candia M. Kenific,Miho Nakajima,Anders P. Mutvei,Pasquale Sansone,Weston Buehring,Huajuan Wang,Juan Pablo Jimenez,Leona Cohen-Gould,Navid Paknejad,Matthew Brendel,Katia Manova-Todorova,Ana Magalhães,José Alexandre Ferreira,Hugo Osório,André M. N. Silva,Ashish Massey,Juan R. Cubillos-Ruiz,Giuseppe Galletti,Paraskevi Giannakakou,Ana Maria Cuervo,John Blenis,Robert E. Schwartz,Mary Sue Brady,Héctor Peinado,Jacqueline Bromberg,Jacqueline Bromberg,Hiroshi Matsui,Celso A. Reis,David Lyden,David Lyden +45 more
TL;DR: It is shown that AF4 can serve as an improved analytical tool for isolating extracellular vesicles and addressing the complexities of heterogeneous nanoparticle subpopulations, and three nanoparticle subsets demonstrated diverse organ biodistribution patterns, suggesting distinct biological functions.
Journal ArticleDOI
Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers
Ayuko Hoshino,Ayuko Hoshino,Han Sang Kim,Han Sang Kim,Linda Bojmar,Linda Bojmar,Linda Bojmar,Kofi Ennu Gyan,Michele Cioffi,Jonathan M. Hernandez,Jonathan M. Hernandez,Jonathan M. Hernandez,Constantinos P. Zambirinis,Constantinos P. Zambirinis,Gonçalo Rodrigues,Gonçalo Rodrigues,Henrik Molina,Søren Heissel,Milica Tesic Mark,Loïc Steiner,Loïc Steiner,Alberto Benito-Martin,Serena Lucotti,Angela Di Giannatale,Katharine Offer,Miho Nakajima,Caitlin Williams,Laura Nogués,Laura Nogués,Fanny A. Pelissier Vatter,Ayako Hashimoto,Ayako Hashimoto,Ayako Hashimoto,Alexander E. Davies,Daniela Freitas,Daniela Freitas,Candia M. Kenific,Yonathan Ararso,Weston Buehring,Pernille Lauritzen,Yusuke Ogitani,Kei Sugiura,Kei Sugiura,Naoko Takahashi,Maša Alečković,Kayleen A. Bailey,Joshua S. Jolissant,Joshua S. Jolissant,Huajuan Wang,Ashton Harris,L. Miles Schaeffer,Guillermo García-Santos,Guillermo García-Santos,Zoe Posner,Vinod P. Balachandran,Yasmin Khakoo,G. Praveen Raju,Avigdor Scherz,Irit Sagi,Ruth Scherz-Shouval,Yosef Yarden,Moshe Oren,Mahathi Malladi,Mary Petriccione,Kevin C. De Braganca,Maria Donzelli,Cheryl Fischer,Stephanie Vitolano,Geraldine P. Wright,Lee Ganshaw,Mariel Marrano,Amina Ahmed,Joe DeStefano,Enrico Danzer,Michael H.A. Roehrl,Norman J. Lacayo,Theresa C. Vincent,Theresa C. Vincent,Martin R. Weiser,Mary S. Brady,Paul A. Meyers,Leonard H. Wexler,Srikanth R. Ambati,Alexander J. Chou,Emily K. Slotkin,Shakeel Modak,Stephen S. Roberts,Ellen M. Basu,Daniel Diolaiti,Benjamin A. Krantz,Benjamin A. Krantz,Fatima Cardoso,Amber L. Simpson,Michael F. Berger,Charles M. Rudin,Diane M. Simeone,Maneesh Jain,Cyrus M. Ghajar,Surinder K. Batra,Ben Z. Stanger,Jack D. Bui,Kristy A. Brown,Vinagolu K. Rajasekhar,John H. Healey,Maria de Sousa,Maria de Sousa,Kim Kramer,Sujit Sheth,Jeanine Baisch,Virginia Pascual,Todd E. Heaton,Michael P. La Quaglia,David J. Pisapia,Robert E. Schwartz,Haiying Zhang,Yuan Liu,Arti Shukla,Laurence Blavier,Yves A. DeClerck,Mark A. LaBarge,Mina J. Bissell,Thomas C. Caffrey,Paul M. Grandgenett,Michael A. Hollingsworth,Jacqueline Bromberg,Jacqueline Bromberg,Bruno Costa-Silva,Héctor Peinado,Yibin Kang,Benjamin A. Garcia,Eileen M. O'Reilly,David P. Kelsen,Tanya M. Trippett,David R. Jones,Irina Matei,William R. Jarnagin,David Lyden +136 more
TL;DR: EVP proteins can serve as reliable biomarkers for cancer detection and determining cancer type, and a panel of tumor-type-specific EVP proteins in TEs and plasma are defined, which can classify tumors of unknown primary origin.
Journal ArticleDOI
Tumour exosomal CEMIP protein promotes cancer cell colonization in brain metastasis
Gonçalo Rodrigues,Gonçalo Rodrigues,Ayuko Hoshino,Ayuko Hoshino,Ayuko Hoshino,Candia M. Kenific,Irina Matei,Loïc Steiner,Loïc Steiner,Daniela Freitas,Han Sang Kim,Han Sang Kim,Peter R. Oxley,Ilana Scandariato,Irene Casanova-Salas,Jinxiang Dai,Chaitanya R. Badwe,Brunilde Gril,Milica Tesic Mark,Brian D. Dill,Henrik Molina,Haiying Zhang,Alberto Benito-Martin,Linda Bojmar,Yonathan Ararso,Katharine Offer,Quincey LaPlant,Weston Buehring,Huajuan Wang,Xinran Jiang,Tyler M. Lu,Yuan Liu,Joshua K. Sabari,Sandra J. Shin,Navneet Narula,Paula S. Ginter,Vinagolu K. Rajasekhar,John H. Healey,Etienne Meylan,Bruno Costa-Silva,Shizhen Emily Wang,Shahin Rafii,Nasser K. Altorki,Charles M. Rudin,David R. Jones,Patricia S. Steeg,Héctor Peinado,Cyrus M. Ghajar,Jacqueline Bromberg,Jacqueline Bromberg,Maria de Sousa,Maria de Sousa,David J. Pisapia,David Lyden +53 more
TL;DR: It is demonstrated that pre-conditioning the brain microenvironment with exosomes from brain metastatic cells enhances cancer cell outgrowth, and that targeting exosomal CEMIP could constitute a future avenue for the prevention and treatment of brain metastasis.
Journal ArticleDOI
Variant ribosomal RNA alleles are conserved and exhibit tissue-specific expression
Matthew Parks,Chad M. Kurylo,Randall A. Dass,Linda Bojmar,Linda Bojmar,Linda Bojmar,David Lyden,David Lyden,C. Theresa Vincent,C. Theresa Vincent,Scott C. Blanchard +10 more
TL;DR: Analysis of whole-genome sequencing data finds that rDNA copy number varies widely across individuals, and pervasive intra- and interindividual nucleotide variation in the 5S, 5.8S, 18S, and 28S ribosomal RNA (rRNA) genes of both human and mouse is identified.