Crystalline metal-organic frameworks (MOFs) are formed by reticular synthesis, which creates strong bonds between inorganic and organic units. Careful selection of MOF constituents can yield crystals of ultrahigh porosity and high thermal and chemical stability. These characteristics allow the interior of MOFs to be chemically altered for use in gas separation, gas storage, and catalysis, among other applications. The precision commonly exercised in their chemical modification and the ability to expand their metrics without changing the underlying topology have not been achieved with other solids. MOFs whose chemical composition and shape of building units can be multiply varied within a particular structure already exist and may lead to materials that offer a synergistic combination of properties.

The Chemistry and Applications of Metal-Organic Frameworks

Deposits of clastic carbonate-dominated (calciclastic) sedimentary slope systems in the rock record have been identified mostly as linearly-consistent carbonate apron deposits, even though most ancient clastic carbonate slope deposits fit the submarine fan systems better. Calciclastic submarine fans are consequently rarely described and are poorly understood. Subsequently, very little is known especially in mud-dominated calciclastic submarine fan systems. Presented in this study are a sedimentological core and petrographic characterisation of samples from eleven boreholes from the Lower Carboniferous of Bowland Basin (Northwest England) that reveals a >250 m thick calciturbidite complex deposited in a calciclastic submarine fan setting. Seven facies are recognised from core and thin section characterisation and are grouped into three carbonate turbidite sequences. They include: 1) Calciturbidites, comprising mostly of highto low-density, wavy-laminated bioclast-rich facies; 2) low-density densite mudstones which are characterised by planar laminated and unlaminated muddominated facies; and 3) Calcidebrites which are muddy or hyper-concentrated debrisflow deposits occurring as poorly-sorted, chaotic, mud-supported floatstones. These

Phd by thesis

J. Appl. Cryst.の発刊に際して

Metal–organic frameworks (MOFs) display a wide range of luminescent behaviors resulting from the multifaceted nature of their structure. In this critical review we discuss the origins of MOF luminosity, which include the linker, the coordinated metal ions, antenna effects, excimer and exciplex formation, and guest molecules. The literature describing these effects is comprehensively surveyed, including a categorization of each report according to the type of luminescence observed. Finally, we discuss potential applications of luminescent MOFs. This review will be of interest to researchers and synthetic chemists attempting to design luminescent MOFs, and those engaged in the extension of MOFs to applications such as chemical, biological, and radiation detection, medical imaging, and electro-optical devices (141 references).

Luminescent Metal–Organic Frameworks

The accidental discovery of the anticancer properties of cisplatin and its clinical introduction in the 1970s represent a major landmark in the history of successful anticancer drugs. Although carboplatin--a second-generation analogue that is safer but shows a similar spectrum of activity to cisplatin--was introduced in the 1980s, the pace of further improvements slowed for many years. However, in the past several years interest in platinum drugs has increased. Key developments include the elucidation of mechanisms of tumour resistance to these drugs, the introduction of new platinum-based agents (oxaliplatin, satraplatin and picoplatin), and clinical combination studies using platinum drugs with resistance modulators or new molecularly targeted drugs.

The resurgence of platinum-based cancer chemotherapy

Neutral transition metal complexes with the tridentate ligand 4-(5-methyl-4-imidazolyl)-3-thiabutanoic acid. A series of isostructural octahedral compounds

Iron coordination in soybean lipoxygenase-1

The synthesis and complex formation with copper(II) of a new symmetric octadentate N6O2 ligand is described. The ligand 1,1,10,10-tetrakis(1-methylbenzimidazol-2-ylmethyl)-1,10-diaza-4,7-dioxadecane (megtb) is prepared by condensation of o-phenylenediamine and [ethylene-bis(oxyethylenenitrilo)]tetraacetic acid, followed by methylation. This ligand appears to yield dinuclear compounds with copper(II) salts with different kinds of bridging anions. Some spectroscopic and magnetic properties of these compounds, as well as the structure of a representative compound Cu2(megtb)F2(BF4)2(H2O) 2, are reported as examples

Synthesis and complex formation of a novel, flexible, biomimetic, benzimidazole‐containing, dinucleating ligand

The formation of a planar 2D hydrogen-bonded network between DNA bases and formate residues is reported, leading to unprecedented parallel sheets of DNA analogues.

Nucleic acids in two dimensions : layers of base pairs linked by carboxylate

https://scholarlypublications.universiteitleiden.nl/access/item%3A2906304/view

Jan Reedijk

Papers

Neutral transition metal complexes with the tridentate ligand 4-(5-methyl-4-imidazolyl)-3-thiabutanoic acid. A series of isostructural octahedral compounds

Iron coordination in soybean lipoxygenase-1

Synthesis and complex formation of a novel, flexible, biomimetic, benzimidazole‐containing, dinucleating ligand

Nucleic acids in two dimensions : layers of base pairs linked by carboxylate

Row 7 of the periodic table complete: Can we expect more new elements; and if so, when?