J
Jan Reedijk
Researcher at Leiden University
Publications - 1165
Citations - 45902
Jan Reedijk is an academic researcher from Leiden University. The author has contributed to research in topics: Ligand & Crystal structure. The author has an hindex of 80, co-authored 1163 publications receiving 43747 citations. Previous affiliations of Jan Reedijk include Nagoya City University & University of Münster.
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Mono- and dinuclear platinum(II) compounds with 5,7-dimethyl-1,2,4-triazolo[1,5-a]pyrimidine. Structure, cytotoxic activity and reaction with 5′-GMP
TL;DR: This compound is the first in which the same triazolopyrimidine ligand (dmtp) coordinates to a metal ion in two different ways, i.e. bridging bidentate and non-bridging monodentate.
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Parameterization of azole‐bridged dinuclear platinum anticancer drugs via a QM/MM force matching procedure
Katrin Spiegel,Alessandra Magistrato,Patrick Maurer,Paolo Ruggerone,Ursula Rothlisberger,Paolo Carloni,Jan Reedijk,Michael L. Klein +7 more
TL;DR: The force match approach significantly extends the potentialities of molecular simulations in the study of anticancer drugs and of the interactions with their biological targets through a recently proposed force matching procedure of the classical forces to ab initio forces obtained from QM/MM trajectories.
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Reactions of unsymmetrically substituted derivatives of cisplatin with short oligodeoxynucleotides containing a -GpG- sequence: H-bonding interactions in pGpG moieties cross-linked by an asymmetric platinum complex enhancing the formation of one geometrical isomer
TL;DR: The interaction of unsymmetrically substituted cisplatin derivatives (general formula cis-Pt(LL'), L=NH 3 ) with 1 H and 31 P NMR spectroscopy has been studied by as discussed by the authors.
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Copper(II) compounds of the planar-tridentate ligand 2,6-bis(pyrazol-3-yl)pyridine
TL;DR: The tridentate ligand 2,6-bis(pyrazol-3-yl)pyridine (dPzPy) renders coordination compounds with halide, nitrate and tetrafluoroborate salts of copper as discussed by the authors.
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Spin crossover in hexakis(1-(2-chloroethyl)-tetrazole)iron(II) complexes; synthesis and magnetic properties
TL;DR: In this article, the spin-crossover complexes [Fe(teec)6](X)2 (with teec=1-(2-chloroethyl)-tetrazole and X=BF4, ClO4, PF6) possess two iron(II) sites each having a different spin crossover behaviour.