J
Josh C. Denny
Researcher at Vanderbilt University Medical Center
Publications - 9
Citations - 741
Josh C. Denny is an academic researcher from Vanderbilt University Medical Center. The author has contributed to research in topics: Skin cancer & Population. The author has an hindex of 6, co-authored 9 publications receiving 472 citations.
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Journal ArticleDOI
Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.
Ayush Giri,Jacklyn N. Hellwege,Jacob M. Keaton,Jacob M. Keaton,Jihwan Park,Chengxiang Qiu,Helen R. Warren,Helen R. Warren,Eric S. Torstenson,Eric S. Torstenson,Csaba P. Kovesdy,Yan V. Sun,Otis D. Wilson,Otis D. Wilson,Cassianne Robinson-Cohen,Christianne L. Roumie,Cecilia P. Chung,K A Birdwell,K A Birdwell,Scott M. Damrauer,Scott L. DuVall,Derek Klarin,Kelly Cho,Yu Wang,Evangelos Evangelou,Evangelos Evangelou,Claudia P. Cabrera,Claudia P. Cabrera,Louise V. Wain,Louise V. Wain,Rojesh Shrestha,Brian S. Mautz,Elvis A. Akwo,Muralidharan Sargurupremraj,Stéphanie Debette,Michael Boehnke,Laura J. Scott,Jian'an Luan,Zhao J-H.,Sara M. Willems,Sébastien Thériault,Nabi Shah,Nabi Shah,Christopher Oldmeadow,Peter Almgren,Ruifang Li-Gao,Niek Verweij,Thibaud Boutin,Massimo Mangino,Massimo Mangino,Ioanna Ntalla,Elena V. Feofanova,Praveen Surendran,James P. Cook,Savita Karthikeyan,Najim Lahrouchi,Ching-Ti Liu,Nuno Sepúlveda,Tom G. Richardson,Aldi T. Kraja,Philippe Amouyel,Martin Farrall,Neil Poulter,Markku Laakso,Eleftheria Zeggini,Peter S. Sever,Robert A. Scott,Claudia Langenberg,Nicholas J. Wareham,David Conen,Palmer Cna.,John Attia,Daniel I. Chasman,Paul M. Ridker,Olle Melander,Dennis O. Mook-Kanamori,Harst Pvd.,Francesco Cucca,David Schlessinger,Caroline Hayward,Tim D. Spector,Jarvelin M-R.,Branwen J. Hennig,Branwen J. Hennig,Nicholas J. Timpson,Wei W-Q.,J C Smith,Yaomin Xu,Michael E. Matheny,E E Siew,C M Lindgren,C M Lindgren,C M Lindgren,Herzig K-H.,George Dedoussis,Josh C. Denny,Bruce M. Psaty,Howson Jmm.,Patricia B. Munroe,Patricia B. Munroe,Christopher Newton-Cheh,Mark J. Caulfield,Mark J. Caulfield,Paul Elliott,Paul Elliott,J M Gaziano,J M Gaziano,John Concato,Wilson Pwf.,Philip S. Tsao,D.R. Velez Edwards,D.R. Velez Edwards,Katalin Susztak,Christopher J. O'Donnell,Adriana M. Hung,Adriana M. Hung,Todd L. Edwards,Todd L. Edwards +117 more
TL;DR: Analysis of blood pressure data from the Million Veteran Program trans-ethnic cohort identifies common and rare variants, and genetically predicted gene expression across multiple tissues associated with systolic, diastolic and pulse pressure in over 775,000 individuals.
Journal ArticleDOI
Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease
Tom R. Webb,Jeanette Erdmann,Kathleen Stirrups,Nathan O. Stitziel,Nicholas G. D. Masca,Henning Jansen,Stavroula Kanoni,Christopher P. Nelson,Paola G. Ferrario,Inke R. König,John D. Eicher,Andrew D. Johnson,Stephen E. Hamby,Christer Betsholtz,Arno Ruusalepp,Oscar Franzén,Eric E. Schadt,Johan Björkegren,Peter Weeke,Paul L. Auer,Ursula M. Schick,Ursula M. Schick,Yingchang Lu,He Zhang,Marie-Pierre Dubé,Anuj Goel,Martin Farrall,Gina M. Peloso,Hong-Hee Won,Ron Do,Erik P A Van Iperen,Jochen Kruppa,Anubha Mahajan,Robert A. Scott,Christina Willenborg,Peter S. Braund,Julian C. van Capelleveen,Alex S. F. Doney,Louise A. Donnelly,Rosanna Asselta,Pier Angelica Merlini,Stefano Duga,Nicola Marziliano,Josh C. Denny,Christian M. Shaffer,Nour Eddine El-Mokhtari,Andre Franke,Stefanie Heilmann,Christian Hengstenberg,Per Hoffmann,Oddgeir L. Holmen,Kristian Hveem,Jan-Håkan Jansson,Karl-Heinz Jöckel,Thorsten Kessler,Jennifer Kriebel,Karl L. Laugwitz,Eirini Marouli,Nicola Martinelli,Mark I. McCarthy,Natalie R. van Zuydam,Christa Meisinger,Tõnu Esko,Tõnu Esko,Tõnu Esko,Evelin Mihailov,Stefan A. Escher,Maris Alver,Susanne Moebus,Andrew D. Morris,Jarma Virtamo,Majid Nikpay,Oliviero Olivieri,Sylvie Provost,Alaa AlQarawi,Neil R. Robertson,Karen O. Akinsansya,Dermot F. Reilly,Thomas F. Vogt,Wu Yin,Folkert W. Asselbergs,Folkert W. Asselbergs,Charles Kooperberg,Rebecca D. Jackson,Eli A. Stahl,Martina Müller-Nurasyid,Konstantin Strauch,Tibor V. Varga,Melanie Waldenberger,Lingyao Zeng,Rajiv Chowdhury,Veikko Salomaa,Ian Ford,J. Wouter Jukema,Philippe Amouyel,Jukka Kontto,Børge G. Nordestgaard,Jean Ferrières,Danish Saleheen,Naveed Sattar,Praveen Surendran,Aline Wagner,Robin Young,Joanna M. M. Howson,Adam S. Butterworth,John Danesh,Diego Ardissino,Erwin P. Bottinger,Raimund Erbel,Paul W. Franks,Domenico Girelli,Alistair S. Hall,G. Kees Hovingh,Adnan Kastrati,Wolfgang Lieb,Thomas Meitinger,William E. Kraus,Svati H. Shah,Ruth McPherson,Marju Orho-Melander,Olle Melander,Andres Metspalu,Colin N. A. Palmer,Annette Peters,Daniel J. Rader,Muredach P. Reilly,Ruth J. F. Loos,Alexander P. Reiner,Alexander P. Reiner,Dan M. Roden,Jean-Claude Tardif,John R. Thompson,Nicholas J. Wareham,Hugh Watkins,Cristen J. Willer,Nilesh J. Samani,Heribert Schunkert,Panos Deloukas,Sekar Kathiresan +138 more
TL;DR: Several CAD loci show substantial pleiotropy, which may help us understand the mechanisms by which these loci affect CAD risk, and identify 6 new loci associated with CAD at genome-wide significance.
Journal ArticleDOI
Electronic health record design and implementation for pharmacogenomics: a local perspective
Josh F. Peterson,Erica Bowton,Julie R. Field,Marc Beller,Jennifer Mitchell,Jonathan S. Schildcrout,William M. Gregg,Kevin B. Johnson,Jim Jirjis,Dan M. Roden,Jill M. Pulley,Josh C. Denny +11 more
TL;DR: The design of a locally developed electronic health record supporting pharmacogenomics has generalizable utility and the challenge of representing genomic data in a comprehensible and clinically actionable format is discussed along with reflection on the scalability of the model to larger sets of genomic data.
Journal ArticleDOI
Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease (vol 374, pg 1134, 2016)
Nathan O. Stitziel,Kathleen Stirrups,Nicholas G. D. Masca,Jeanette Erdmann,Paola G. Ferrario,Inke R. Koenig,Peter Weeke,Tom R. Webb,Paul L. Auer,Ursula M. Schick,Yingchang Lu,He Zhang,Marie-Pierre Dubé,Anuj Goel,Martin Farrall,Gina M. Peloso,Hong-Hee Won,Ron Do,Erik P A Van Iperen,Stavroula Kanoni,Jochen Kruppa,Anubha Mahajan,Robert A. Scott,Christina Willenborg,Peter S. Braund,Julian C. van Capelleveen,Alex S. F. Doney,Louise A. Donnelly,Rosanna Asselta,Piera Angelica Merlini,Stefano Duga,Nicola Marziliano,Josh C. Denny,Christian M. Shaffer,Nour Eddine El-Mokhtari,Andre Franke,Omri Gottesman,Stefanie Heilmann,Christian Hengstenberg,Per Hoffmann,Oddgeir L. Holmen,Kristian Hveem,Jan-Håkan Jansson,Karl-Heinz Joeckel,Thorsten Kessler,Jennifer Kriebel,Karl L. Laugwitz,Eirini Marouli,Nicola Martinelli,Mark I. McCarthy,Natalie R. van Zuydam,Christa Meisinger,Tõnu Esko,Evelin Mihailov,Stefan A. Escher,Maris Alver,Susanne Moebus,Andrew D. Morris,Martina Müller-Nurasyid,Majid Nikpay,Oliviero Olivieri,Louis-Philippe Lemieux Perreault,Alaa AlQarawi,Neil Robertson,Karen O. Akinsanya,Dermot F. Reilly,Thomas F. Vogt,Wu Yin,Folkert W. Asselbergs,Charles Kooperberg,Rebecca D. Jackson,Eli A. Stahl,Konstantin Strauch,Tibor V. Varga,Melanie Waldenberger,Lingyao Zeng,Aldi T. Kraja,Chunyu Liu,Georg Ehret,Christopher Newton-Cheh,Daniel I. Chasman,Rajiv Chowdhury,Marco M Ferrario,Ian Ford,J. Wouter Jukema,Frank Kee,Kari Kuulasmaa,Børge G. Nordestgaard,Markus Perola,Danish Saleheen,Naveed Sattar,Praveen Surendran,David-Alexandre Trégouët,Robin Young,Joanna M. M. Howson,Adam S. Butterworth,John Danesh,Diego Ardissino,Erwin P. Bottinger,Raimund Erbel,Paul W. Franks,Domenico Girelli,Alistair S. Hall,G. Kees Hovingh,Adnan Kastrati,Wolfgang Lieb,Thomas Meitinger,William E. Kraus,Svati H. Shah,Ruth McPherson,Marju Orho-Melander,Olle Melander,Andres Metspalu,Colin N. A. Palmer,Annette Peters,Daniel J. Rader,Muredach P. Reilly,Ruth J. F. Loos,Alex P. Reiner,Dan M. Roden,Jean-Claude Tardif,John Thompson,Nicholas J. Wareham,Hugh Watkins,Cristen J. Willer,Sekar Kathiresan,Panos Deloukas,Nilesh J. Samani,Heribert Schunkert +128 more
Journal ArticleDOI
Uncovering exposures responsible for birth season - disease effects: a global study.
Mary Regina Boland,Pradipta Parhi,Li Li,Riccardo Miotto,Robert J. Carroll,Usman Iqbal,Usman Iqbal,Phung Anh Nguyen,Phung Anh Nguyen,Martijn J. Schuemie,Martijn J. Schuemie,Seng Chan You,Seng Chan You,Donahue Smith,Sean D. Mooney,Patrick B. Ryan,Patrick B. Ryan,Yu-Chuan Jack Li,Yu-Chuan Jack Li,Rae Woong Park,Rae Woong Park,Josh C. Denny,Joel T. Dudley,George Hripcsak,Pierre Gentine,Nicholas P. Tatonetti +25 more
TL;DR: A global study of birth month–disease relationships reveals distal risk factors involved in causal biological pathways that underlie them.