M
Margaret R. Karagas
Researcher at Dartmouth College
Publications - 528
Citations - 28181
Margaret R. Karagas is an academic researcher from Dartmouth College. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 84, co-authored 430 publications receiving 24195 citations. Previous affiliations of Margaret R. Karagas include Dartmouth–Hitchcock Medical Center.
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Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33
Zhaoming Wang,Bin Zhu,Mingfeng Zhang,Hemang Parikh,Jinping Jia,Charles C. Chung,Joshua N. Sampson,Jason W. Hoskins,Amy Hutchinson,Laurie Burdette,Abdisamad M. Ibrahim,Christopher Hautman,Preethi S. Raj,Christian C. Abnet,Andrew A. Adjei,Anders Ahlbom,Demetrius Albanes,Naomi E. Allen,Christine B. Ambrosone,Melinda C. Aldrich,Pilar Amiano,Christopher I. Amos,Ulrika Andersson,Gerald L. Andriole,Irene L. Andrulis,Cecilia Arici,Alan A. Arslan,Melissa A. Austin,Dalsu Baris,Donald A. Barkauskas,Bryan A. Bassig,Laura E. Beane Freeman,Christine D. Berg,Sonja I. Berndt,Pier Alberto Bertazzi,Richard B. Biritwum,Amanda Black,William J. Blot,Heiner Boeing,Paolo Boffetta,Kelly L. Bolton,Marie-Christine Boutron-Ruault,Paige M. Bracci,Paul Brennan,Louise A. Brinton,Michelle Brotzman,H. Bas Bueno-de-Mesquita,Julie E. Buring,Mary Ann Butler,Qiuyin Cai,Geraldine Cancel-Tassin,Federico Canzian,Guangwen Cao,Neil E. Caporaso,Alfredo Carrato,Tania Carreón,Angela Carta,Gee-Chen Chang,I-Shou Chang,Jenny Chang-Claude,Xu Che,Chien-Jen Chen,Chih Yi Chen,Chung-Hsing Chen,Constance Chen,Kuan-Yu Chen,Yuh Min Chen,Anand P. Chokkalingam,Lisa W. Chu,Françoise Clavel-Chapelon,Graham A. Colditz,Joanne S. Colt,David V. Conti,Michael B. Cook,Victoria K. Cortessis,E. David Crawford,Olivier Cussenot,Faith G. Davis,Immaculata De Vivo,Xiang Deng,Ti Ding,Colin P.N. Dinney,Anna Luisa Di Stefano,W. Ryan Diver,Eric J. Duell,Joanne W. Elena,Jin-Hu Fan,Heather Spencer Feigelson,Maria Feychting,Jonine D. Figueroa,Adrienne M. Flanagan,Joseph F. Fraumeni,Neal D. Freedman,Brooke L. Fridley,Charles S. Fuchs,Manuela Gago-Dominguez,Steven Gallinger,Yu-Tang Gao,Susan M. Gapstur,Montserrat Garcia-Closas,Reina Garcia-Closas,Julie M. Gastier-Foster,J. Michael Gaziano,Daniela S. Gerhard,Carol Giffen,Graham G. Giles,Elizabeth M. Gillanders,Edward Giovannucci,Michael Goggins,Nalan Gokgoz,Alisa M. Goldstein,Carlos González,Richard Gorlick,Mark H. Greene,Myron D. Gross,H. Barton Grossman,Robert L. Grubb,Jian Gu,Peng Guan,Christopher A. Haiman,Göran Hallmans,Susan E. Hankinson,Curtis C. Harris,Patricia Hartge,Claudia Maria Hattinger,Richard B. Hayes,Qincheng He,Lee J. Helman,Brian E. Henderson,Roger Henriksson,Judith Hoffman-Bolton,Chancellor Hohensee,Elizabeth A. Holly,Yun-Chul Hong,Robert N. Hoover,H. Dean Hosgood,Chin-Fu Hsiao,Ann W. Hsing,Chao A. Hsiung,Nan Hu,Wei Hu,Zhibin Hu,Ming-Shyan Huang,David J. Hunter,Peter D. Inskip,Hidemi Ito,Eric J. Jacobs,Kevin B. Jacobs,Mazda Jenab,Bu-Tian Ji,Christoffer Johansen,Mattias Johansson,Alison Johnson,Rudolf Kaaks,Ashish M. Kamat,Aruna Kamineni,Margaret R. Karagas,Chand Khanna,Kay-Tee Khaw,Christopher Kim,In-Sam Kim,Jin Hee Kim,Yeul Hong Kim,Young-Chul Kim,Young Tae Kim,Chang Hyun Kang,Yoo Jin Jung,Cari M. Kitahara,Alison P. Klein,Robert J. Klein,Manolis Kogevinas,Woon-Puay Koh,Takashi Kohno,Laurence N. Kolonel,Charles Kooperberg,Christian P. Kratz,Vittorio Krogh,Hideo Kunitoh,Robert C. Kurtz,Nilgun Kurucu,Qing Lan,Mark Lathrop,Ching C. Lau,Fernando Lecanda,Kyoung Mu Lee,Maxwell P. Lee,Loic Le Marchand,Seth P. Lerner,Donghui Li,Linda M. Liao,Wei-Yen Lim,Dongxin Lin,Jie Lin,Sara Lindström,Martha S. Linet,Jolanta Lissowska,Jianjun Liu,Boerje Ljungberg,Josep Lloreta,Daru Lu,Jing Ma,Núria Malats,Satu Männistö,Neyssa Marina,Giuseppe Mastrangelo,Keitaro Matsuo,Katherine A. McGlynn,Roberta McKean-Cowdin,Lorna H. McNeill,Robert R. McWilliams,Beatrice Melin,Paul S. Meltzer,James E. Mensah,Xiaoping Miao,Dominique S. Michaud,Alison M. Mondul,Lee E. Moore,Kenneth Muir,Shelley Niwa,Sara H. Olson,Nick Orr,Salvatore Panico,Jae Yong Park,Alpa V. Patel,Ana Patiño-García,Sofia Pavanello,Petra H.M. Peeters,Beata Peplonska,Ulrike Peters,Gloria M. Petersen,Piero Picci,Malcolm C. Pike,Stefano Porru,Jennifer Prescott,Xia Pu,Mark P. Purdue,You-Lin Qiao,Preetha Rajaraman,Elio Riboli,Harvey A. Risch,Rebecca J. Rodabough,Nathaniel Rothman,Avima M. Ruder,Jeong Seon Ryu,Marc Sanson,Alan R. Schned,Fredrick R. Schumacher,Ann G. Schwartz,Kendra Schwartz,Molly Schwenn,Katia Scotlandi,Adeline Seow,Consol Serra,Massimo Serra,Howard D. Sesso,Gianluca Severi,Hongbing Shen,Min Shen,Sanjay Shete,Kouya Shiraishi,Xiao-Ou Shu,Afshan Siddiq,Luis Sierrasesúmaga,Sabina Sierri,Alan D. L. Sihoe,Debra T. Silverman,Matthias Simon,Melissa C. Southey,Logan G. Spector,Margaret R. Spitz,Meir J. Stampfer,Pär Stattin,Mariana C. Stern,Victoria L. Stevens,Rachael Z. Stolzenberg-Solomon,Daniel O. Stram,Sara S. Strom,Wu Chou Su,Malin Sund,Sook Whan Sung,Anthony J. Swerdlow,Wen Tan,Hideo Tanaka,Wei Tang,Ze-Zhang Tang,Adonina Tardón,Evelyn Tay,Philip R. Taylor,Yao Tettey,David Thomas,Roberto Tirabosco,Anne Tjønneland,Geoffrey S. Tobias,Jorge R. Toro,Ruth C. Travis,Dimitrios Trichopoulos,Rebecca Troisi,Ann Truelove,Ying-Huang Tsai,Margaret A. Tucker,Rosario Tumino,David Van Den Berg,Stephen K. Van Den Eeden,Roel Vermeulen,Paolo Vineis,Kala Visvanathan,Ulla Vogel,Chaoyu Wang,Chengfeng Wang,Junwen Wang,Sophia S. Wang,Elisabete Weiderpass,Stephanie J. Weinstein,Nicolas Wentzensen,William Wheeler,Emily White,John K. Wiencke,Alicja Wolk,Brian M. Wolpin,Maria Pik Wong,Margaret Wrensch,Chen Wu,Tangchun Wu,Xifeng Wu,Yi-Long Wu,Jay S. Wunder,Yong-Bing Xiang,Jun Xu,Hannah P. Yang,Pan-Chyr Yang,Yasushi Yatabe,Yuanqing Ye,Edward D. Yeboah,Zhihua Yin,Chen Ying,Chong-Jen Yu,Kai Yu,Jian-Min Yuan,Krista A. Zanetti,Anne Zeleniuch-Jacquotte,Wei Zheng,Baosen Zhou,Lisa Mirabello,Sharon A. Savage,Peter Kraft,Stephen J. Chanock,Meredith Yeager,M. T. Landi,Jianxin Shi,Nilanjan Chatterjee,Laufey T. Amundadottir +350 more
TL;DR: Allele-specific effects on DNA methylation were seen for a subset of risk loci, indicating that methylation and subsequent effects on gene expression may contribute to the biology of risk variants on 5p15.33, to an extent not previously observed in other cancer susceptibility loci.
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Polymorphisms in nucleotide excision repair genes, arsenic exposure, and non-melanoma skin cancer in New Hampshire.
Katie Lyn Applebaum,Margaret R. Karagas,David J. Hunter,Paul J. Catalano,Steven H. Byler,Steve Morris,Heather H. Nelson +6 more
TL;DR: Findings indicate a reduced NMSC risk in relation to XPD Asp312Asn and Lys751Gln variants, and support the hypothesis that NER polymorphisms may modify the association between N MSC and arsenic.
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Mapping of the UGT1A locus identifies an uncommon coding variant that affects mRNA expression and protects from bladder cancer
Wei Tang,Yi-Ping Fu,Jonine D. Figueroa,Núria Malats,Montserrat Garcia-Closas,Nilanjan Chatterjee,Manolis Kogevinas,Dalsu Baris,Michael J. Thun,Jennifer L. Hall,Immaculata De Vivo,Demetrius Albanes,Patricia Porter-Gill,Mark P. Purdue,Laurie Burdett,Luyang Liu,Amy Hutchinson,Timothy A. Myers,Adonina Tardón,Consol Serra,Alfredo Carrato,Reina García-Closas,Josep Lloreta,Alison Johnson,Molly Schwenn,Margaret R. Karagas,Alan Schned,Amanda Black,Eric J. Jacobs,W. Ryan Diver,Susan M. Gapstur,Jarmo Virtamo,David J. Hunter,Joseph F. Fraumeni,Stephen J. Chanock,Debra T. Silverman,Nathaniel Rothman,Ludmila Prokunina-Olsson +37 more
TL;DR: The study shows an example of genetic and functional role of an uncommon protective genetic variant in a complex human disease, such as bladder cancer, as well as finding the protective T allele of rs17863783 to be associated with increased mRNA expression of UGT1A6.1 protein.
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Estimated exposure to arsenic in breastfed and formula-fed infants in a United States cohort.
Courtney C. Carignan,Kathryn L. Cottingham,Brian P. Jackson,Shohreh F. Farzan,A. Jay Gandolfi,Tracy Punshon,Carol L. Folt,Margaret R. Karagas +7 more
TL;DR: The findings suggest that breastfed infants have lower arsenic exposure than formula-fed infants, and that both formula powder and drinking water can be sources of exposure for U.S. infants.
Journal ArticleDOI
Power and sample size calculations for generalized regression models with covariate measurement error
TL;DR: This paper derives a novel measurement error corrected power function for generalized linear models using a generalized score test based on quasi-likelihood methods and demonstrates the improved properties of the power calculations with simulations and numerical studies.