Peter J. Barnes

TL;DR: Innervation of theAirways distribution of neuropeptides in airways afferent nerves in the airways the cholinergic control of airways autonomic ganglia adrenergic nerves and receptors neuromodulation in airway innervation of airway smooth muscle neural control of the airway vasculature neurogenic inflammation in theairways neural control in the upper respiratory tract abnormal autonomic control in respiratory disease.

TL;DR: There is a wide variation in the reported levels of nitric oxide in exhaled air, suggesting that technical factors are important.

TL;DR: This large, rigorously conducted RCT showed that the combination of low-dose theophylline and prednisone did not affect exacerbation rate in patients with moderate to severe COPD in China.

TL;DR: The review highlights why they are different conditions requiring different approaches to treatment and provides a backdrop for the subsequent chapters in this volume discussing recent advances in the pharmacology and treatment of asthma and COPD.

TL;DR: The review is organized according to the following subheadings: Risk Factors, Natural History, Physiology, Disease Mechanisms, Phenotypes and Biomarkers, Comorbidities, Management, and Exacerbations.