P
Peter J. Barnes
Researcher at National Institutes of Health
Publications - 1554
Citations - 177909
Peter J. Barnes is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Asthma & COPD. The author has an hindex of 194, co-authored 1530 publications receiving 166618 citations. Previous affiliations of Peter J. Barnes include University of Nebraska Medical Center & Novartis.
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Journal ArticleDOI
Measurement of exhaled nitric oxide in children, 2001
Eugenio Baraldi,J. C. De Jongste,Benjamin Gaston,Kjell Alving,Peter J. Barnes,Hans Bisgaard,Andrew Bush,Claude Gaultier,Hartmut Grasemann,John F. Hunt,Niranjan Kissoon,Giorgio Piacentini,Felix Ratjen,Philip E. Silkoff,Stephen M. Stick +14 more
TL;DR: Exhaled nitric oxide measurement has definitely found its way into clinical research in paediatric respiratory medicine, and the merits of this new technique must now be demonstrated in larger studies, using standardised methodology in an appropriate setting.
Journal ArticleDOI
Mechanisms in COPD: Differences From Asthma
TL;DR: In this paper, the eosinophilic inflammation in asthma is markedly suppressed by corticosteroids, but they have no appreciable effect on the inflammation in COPD, consistent with a failure of long-term corticostosteroids to alter the progression of COPD.
Journal ArticleDOI
How Do Corticosteroids Work in Asthma
Peter J. Barnes,Ian M. Adcock +1 more
TL;DR: Understanding how corticosteroids work in patients with asthma may help in designing novel cortiosteroids with less systemic effects, as well as novel anti-inflammatory approaches, and help elucidate the molecular basis of chronic inflammation and why cortingosteroids are ineffective in Patients with steroid-resistant asthma and with chronic obstructive pulmonary disease.
Journal ArticleDOI
Anti-inflammatory Effects of Resveratrol in Lung Epithelial Cells: Molecular Mechanisms
Louise E. Donnelly,Robert Newton,Gina E. Kennedy,Peter Fenwick,Rachel H. F. Leung,Kazuhiro Ito,Richard Russell,Peter J. Barnes +7 more
TL;DR: It is demonstrated that resveratrol and quercetin have novel nonsteroidal anti-inflammatory activity that may have applications for the treatment of inflammatory diseases.