P
Peter J. Barnes
Researcher at National Institutes of Health
Publications - 1554
Citations - 177909
Peter J. Barnes is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Asthma & COPD. The author has an hindex of 194, co-authored 1530 publications receiving 166618 citations. Previous affiliations of Peter J. Barnes include University of Nebraska Medical Center & Novartis.
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VIP and PHM and their role in nonadrenergic inhibitory responses in isolated human airways.
TL;DR: It is concluded that VIP and PHM are more potent bronchodilators of human bronchi than Iso and that the association between the relaxant effects of these peptides and nonadrenergic inhibitory responses suggests that they may be possible neurotransmitters of nonad Renfrewshire inhibitory nerves in human airways.
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NF-κB and Activator Protein 1 Response Elements and the Role of Histone Modifications in IL-1β-Induced TGF-β1 Gene Transcription
TL;DR: The results suggest that IL-1β-stimulated transcription of TGF-β1 is temporally regulated by NF-κB and AP-1 and involves histone hyperacetylation at distinct promoter sites.
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High levels of interleukin-6 in the exhaled breath condensate of patients with COPD.
TL;DR: The increased IL-6 levels in exhaled breath condensate may reflect airway inflammation in patients with COPD.
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Reduced histone deacetylase in COPD : Clinical implications
TL;DR: Antioxidants and inhibitors of nitric oxide synthesis may restore corticosteroid sensitivity in COPD, but this can also be achieved by low doses of theophylline, which is an HDAC activator.
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The electronic nose in respiratory medicine.
TL;DR: E-nose technology might contribute to the identification of new surrogate markers of pulmonary inflammation and subphenotypes of patients with respiratory diseases, provide a molecular basis to a personalized pharmacological treatment, and facilitate the development of new drugs.