Peter J. Barnes

TL;DR: It is shown that the –509T variant on haplotype 1 is the most informative marker of the TGFβ1 contribution to asthma severity.

TL;DR: Treating oxidative stress by antioxidants or enhancing endogenous antioxidants should be an effective strategy to treat the underlying pathogenetic mechanisms of COPD.

TL;DR: It is demonstrated that single vagal afferents may be studied in vitro and the first examination of the properties of sensory fibres innervating guinea‐pig airways is provided, to show marked differences in terms of their chemosensitivity.

TL;DR: The electronic nose has a high diagnostic performance that can be increased when combined with FENO and MS fingerprints of VOCs could discriminate between patients with asthma and healthy subjects.

TL;DR: The findings suggest that the increased expression of COX‐2 is intimately involved in the exaggerated release of prostanoids from HASM cells exposed to pro‐inflammatory cytokines, indicating a role for airway smooth muscle cells, in addition to their contractile function, as inflammatory cells involved inThe production of mediators which may contribute to the inflammatory response seen in diseases such as asthma.