P
Peter J. Barnes
Researcher at National Institutes of Health
Publications - 1554
Citations - 177909
Peter J. Barnes is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Asthma & COPD. The author has an hindex of 194, co-authored 1530 publications receiving 166618 citations. Previous affiliations of Peter J. Barnes include University of Nebraska Medical Center & Novartis.
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Journal ArticleDOI
CXCR3 and CCR5 chemokines in induced sputum from patients with COPD
Cláudia Henrique da Costa,Rogério Rufino,Suzanne L. Traves,José Roberto Lapa e Silva,Peter J. Barnes,Louise E. Donnelly +5 more
TL;DR: CXCR3 chemokines and CCL5 are increased in sputum from COPD patients compared with nonsmokers, and may be important in COPD pathogenesis.
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Increased levels of exhaled carbon monoxide in bronchiectasis: a new marker of oxidative stress
TL;DR: Increased levels of exhaled CO may reflect induction of HO-1 and oxidative stress in bronchiectasis and possibly other chronic inflammatory lung disorders, and measurement of exhale CO may be useful in the management of bronchiECTasis.
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Epigenetics and airways disease.
TL;DR: The expression and activity of enzymes that regulate these epigenetic modifications have been reported to be abnormal in the airways of patients with respiratory disease and there is scope for the development of 'epigenetic therapies' for disease.
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Effect of theophylline on induced sputum inflammatory indices and neutrophil chemotaxis in chronic obstructive pulmonary disease.
Sarah V. Culpitt,Carmen de Matos,Richard Russell,Louise E. Donnelly,Duncan F. Rogers,Peter J. Barnes +5 more
TL;DR: It is suggested that theophylline has antiinflammatory properties that may be useful in the long-term treatment of COPD.
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Bronchial epithelial cells: The key effector cells in the pathogenesis of chronic obstructive pulmonary disease?
TL;DR: An overview of recent insights into the function of the bronchial epithelium in the pathogenesis of COPD is provided and how this may provide novel therapeutic approaches for a number of chronic lung diseases is provided.