P
Peter J. Barnes
Researcher at National Institutes of Health
Publications - 1554
Citations - 177909
Peter J. Barnes is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Asthma & COPD. The author has an hindex of 194, co-authored 1530 publications receiving 166618 citations. Previous affiliations of Peter J. Barnes include University of Nebraska Medical Center & Novartis.
Papers
More filters
Journal ArticleDOI
The prevalence of small airways disease in adult asthma: A systematic literature review
TL;DR: Small airways disease is highly prevalent in asthma, even in patients with milder disease, and its presence should not be underestimated or overlooked as part of the daily management of patients with asthma.
Journal ArticleDOI
New directions in allergic diseases: mechanism-based anti-inflammatory therapies.
TL;DR: Most of the new therapies in development are aimed at inhibiting or suppressing components of the allergic inflammatory response, but in the future, there are possibilities for development of preventive and curative treatments.
Journal ArticleDOI
Dual action of nitric oxide on airway plasma leakage.
TL;DR: Results suggest that under "physiological" conditions endogenous NO suppresses plasma leakage but when iNOS is expressed the increased production of NO enhances plasma leakage, which may implicate a role for NO in the maintenance of airway function and in the inflammatory process occurring in diseases such as asthma.
Journal ArticleDOI
Kinases as Novel Therapeutic Targets in Asthma and Chronic Obstructive Pulmonary Disease
TL;DR: There has been great interest in the development of kinase inhibitors as anti-inflammatory therapies, particular where corticosteroids are less effective, as in severe asthma and COPD.
Journal ArticleDOI
The effect of inhaled vasoactive intestinal peptide on bronchial reactivity to histamine in humans.
Peter J. Barnes,C. M. S. Dixon +1 more
TL;DR: It is concluded that VIP protects against histamine-induced bronchoconstriction in human airways in vivo, and therefore has the capacity to be the neurotransmitter of nonadrenergic, noncholinergic inhibitory nerves in humanAirway smooth muscle.