R
Rosaline W. Macharia
Researcher at University of Nairobi
Publications - 18
Citations - 413
Rosaline W. Macharia is an academic researcher from University of Nairobi. The author has contributed to research in topics: Tsetse fly & Gene. The author has an hindex of 6, co-authored 14 publications receiving 334 citations. Previous affiliations of Rosaline W. Macharia include International Centre of Insect Physiology and Ecology & South African National Bioinformatics Institute.
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Journal ArticleDOI
Genome sequence of the tsetse fly (Glossina morsitans ): Vector of African trypanosomiasis
Junichi Watanabe,Masahira Hattori,Matthew Berriman,Michael J. Lehane,Neil Hall,Neil Hall,Philippe Solano,Serap Aksoy,Winston Hide,Winston Hide,Yeya T. Touré,Geoffrey M. Attardo,Alistair C. Darby,Atsushi Toyoda,Christiane Hertz-Fowler,Denis M. Larkin,James Cotton,Mandy Sanders,Martin T. Swain,Michael A. Quail,Noboru Inoue,Sophie Ravel,Todd D. Taylor,Tulika P. Srivastava,Vineet K. Sharma,Wesley C. Warren,Richard K. Wilson,Yutaka Suzuki,Daniel Lawson,Daniel S.T. Hughes,Karyn Megy,Daniel K. Masiga,Paul O. Mireji,Immo A. Hansen,Jan Van Den Abbeele,Joshua B. Benoit,Joshua B. Benoit,Kostas Bourtzis,Kostas Bourtzis,Kostas Bourtzis,George F. Obiero,George F. Obiero,Hugh M. Robertson,Jeffery W. Jones,Jing-Jiang Zhou,Linda M. Field,Markus Friedrich,Steven G. Nyanjom,Erich Loza Telleria,Guy Caljon,José M. C. Ribeiro,Alvaro Acosta-Serrano,Cher-Pheng Ooi,Clair Rose,David P. Price,Lee R. Haines,Alan Christoffels,Cheolho Sim,Daphne Q.-D. Pham,David L. Denlinger,Dawn L. Geiser,Irene Omedo,Joy J. Winzerling,Justin T. Peyton,Kevin K. Marucha,Mario Jonas,Megan E. Meuti,Neil D. Rawlings,Qirui Zhang,Rosaline W. Macharia,Rosaline W. Macharia,Veronika Michalkova,Veronika Michalkova,Zahra Jalali Sefid Dashti,Aaron A. Baumann,Gerd Gäde,Heather G. Marco,Jelle Caers,Liliane Schoofs,Michael A. Riehle,Wanqi Hu,Zhijian Tu,Aaron M. Tarone,Anna R. Malacrida,Caleb K. Kibet,Francesca Scolari,J.J.O. Koekemoer,Judith H. Willis,Ludvik M. Gomulski,Marco Falchetto,Maxwell J. Scott,Shuhua Fu,Sing-Hoi Sze,Thiago Luiz,Brian L. Weiss,Deirdre Walshe,Jingwen Wang,Mark Wamalwa,Mark Wamalwa,Sarah Mwangi,Urvashi N. Ramphul,Anna K. Snyder,Corey L. Brelsfoard,Gavin H. Thomas,George Tsiamis,Peter Arensburger,Rita V. M. Rio,Sandy J. Macdonald,Sumir Panji,Sumir Panji,Adele Kruger,Alia Benkahla,Apollo Simon Peter Balyeidhusa,Atway R. Msangi,Chinyere K. Okoro,Dawn Stephens,Eleanor J Stanley,Feziwe Mpondo,Florence N. Wamwiri,Furaha Mramba,Geoffrey H. Siwo,George Githinji,Gordon William Harkins,Grace Murilla,Heikki Lehväslaiho,Imna I. Malele,Joanna E. Auma,Johnson Kinyua,Johnson O. Ouma,Loyce M. Okedi,Lucien Manga,Martin Aslett,Mathurin Koffi,Michael W. Gaunt,Mmule Makgamathe,Nicola Mulder,Oliver Manangwa,Patrick P. Abila,Patrick Wincker,Richard Gregory,Rosemary Bateta,Ryuichi Sakate,Sheila C. Ommeh,Stella Lehane,Tadashi Imanishi,Victor Chukwudi Osamor,Yoshihiro Kawahara,Yoshihiro Kawahara +147 more
TL;DR: The sequence and annotation of the 366-megabase Glossina mors Titans morsitans genome are described, providing a foundation for research into trypanosomiasis prevention and yield important insights with broad implications for multiple aspects of tsetse biology.
Journal ArticleDOI
Comparative genomic analysis of six Glossina genomes, vectors of African trypanosomes
Geoffrey M. Attardo,Adly M. M. Abd-Alla,Alvaro Acosta-Serrano,James E. Allen,Rosemary Bateta,Joshua B. Benoit,Kostas Bourtzis,Jelle Caers,Guy Caljon,Mikkel B. Christensen,David W. Farrow,Markus Friedrich,Aurélie Hua-Van,Emily C. Jennings,Denis M. Larkin,Daniel Lawson,Michael J. Lehane,Vasileios Panagiotis Lenis,Ernesto Lowy-Gallego,Rosaline W. Macharia,Anna R. Malacrida,Heather G. Marco,Daniel K. Masiga,Gareth Maslen,Irina Matetovici,Richard P. Meisel,Irene K. Meki,Veronika Michalkova,Veronika Michalkova,Wolfgang J. Miller,Patrick Minx,Paul O. Mireji,Lino Ometto,Andrew G. Parker,Rita V. M. Rio,Clair Rose,Andrew J. Rosendale,Andrew J. Rosendale,Omar Rota-Stabelli,Grazia Savini,Liliane Schoofs,Francesca Scolari,Martin T. Swain,Peter Takac,Chad Tomlinson,George Tsiamis,Jan Van Den Abbeele,Aurélien Vigneron,Jingwen Wang,Wesley C. Warren,Wesley C. Warren,Robert M. Waterhouse,Matthew T. Weirauch,Brian L. Weiss,Richard K. Wilson,Xin Zhao,Serap Aksoy +56 more
TL;DR: Compared genomic analyses validate established evolutionary relationships and sub-genera and provide insight into the evolutionary biology underlying novel adaptations and are relevant to applied aspects of vector control such as trap design and discovery of novel pest and disease control strategies.
Journal ArticleDOI
Genome-Wide Comparative Analysis of Chemosensory Gene Families in Five Tsetse Fly Species.
Rosaline W. Macharia,Rosaline W. Macharia,Paul O. Mireji,Edwin Murungi,Grace Murilla,Alan Christoffels,Serap Aksoy,Daniel K. Masiga +7 more
TL;DR: This work identified and annotated the major chemosensory gene families in Glossina and identified, in all species, homologs of Ir84a; a Drosophila-specific ionotropic receptor that promotes male courtship suggesting that this is a conserved trait in tsetse flies.
Journal ArticleDOI
Insects' RNA Profiling Reveals Absence of "Hidden Break" in 28S Ribosomal RNA Molecule of Onion Thrips, Thrips tabaci.
TL;DR: It is shown that RNA from a given insect order does not conform to a particular banding profile and therefore this approach cannot be reliably used to characterize newly discovered species.
Journal ArticleDOI
Target-similarity search using Plasmodium falciparum proteome identifies approved drugs with anti-malarial activity and their possible targets
Reagan M. Mogire,Hoseah M. Akala,Rosaline W. Macharia,Dennis W. Juma,Agnes C. Cheruiyot,Ben Andagalu,Mathew L. Brown,Hany A. El-Shemy,Steven G. Nyanjom +8 more
TL;DR: The study results validate the use of proteome-wide target similarity approach in identifying approved drugs with activity against P. falciparum and could be adapted for other pathogens.