G
Guy Caljon
Researcher at University of Antwerp
Publications - 143
Citations - 2701
Guy Caljon is an academic researcher from University of Antwerp. The author has contributed to research in topics: Trypanosoma brucei & Leishmania infantum. The author has an hindex of 25, co-authored 124 publications receiving 2029 citations. Previous affiliations of Guy Caljon include Vrije Universiteit Brussel & Flanders Institute for Biotechnology.
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Journal ArticleDOI
Genome sequence of the tsetse fly (Glossina morsitans ): Vector of African trypanosomiasis
Junichi Watanabe,Masahira Hattori,Matthew Berriman,Michael J. Lehane,Neil Hall,Neil Hall,Philippe Solano,Serap Aksoy,Winston Hide,Winston Hide,Yeya T. Touré,Geoffrey M. Attardo,Alistair C. Darby,Atsushi Toyoda,Christiane Hertz-Fowler,Denis M. Larkin,James Cotton,Mandy Sanders,Martin T. Swain,Michael A. Quail,Noboru Inoue,Sophie Ravel,Todd D. Taylor,Tulika P. Srivastava,Vineet K. Sharma,Wesley C. Warren,Richard K. Wilson,Yutaka Suzuki,Daniel Lawson,Daniel S.T. Hughes,Karyn Megy,Daniel K. Masiga,Paul O. Mireji,Immo A. Hansen,Jan Van Den Abbeele,Joshua B. Benoit,Joshua B. Benoit,Kostas Bourtzis,Kostas Bourtzis,Kostas Bourtzis,George F. Obiero,George F. Obiero,Hugh M. Robertson,Jeffery W. Jones,Jing-Jiang Zhou,Linda M. Field,Markus Friedrich,Steven G. Nyanjom,Erich Loza Telleria,Guy Caljon,José M. C. Ribeiro,Alvaro Acosta-Serrano,Cher-Pheng Ooi,Clair Rose,David P. Price,Lee R. Haines,Alan Christoffels,Cheolho Sim,Daphne Q.-D. Pham,David L. Denlinger,Dawn L. Geiser,Irene Omedo,Joy J. Winzerling,Justin T. Peyton,Kevin K. Marucha,Mario Jonas,Megan E. Meuti,Neil D. Rawlings,Qirui Zhang,Rosaline W. Macharia,Rosaline W. Macharia,Veronika Michalkova,Veronika Michalkova,Zahra Jalali Sefid Dashti,Aaron A. Baumann,Gerd Gäde,Heather G. Marco,Jelle Caers,Liliane Schoofs,Michael A. Riehle,Wanqi Hu,Zhijian Tu,Aaron M. Tarone,Anna R. Malacrida,Caleb K. Kibet,Francesca Scolari,J.J.O. Koekemoer,Judith H. Willis,Ludvik M. Gomulski,Marco Falchetto,Maxwell J. Scott,Shuhua Fu,Sing-Hoi Sze,Thiago Luiz,Brian L. Weiss,Deirdre Walshe,Jingwen Wang,Mark Wamalwa,Mark Wamalwa,Sarah Mwangi,Urvashi N. Ramphul,Anna K. Snyder,Corey L. Brelsfoard,Gavin H. Thomas,George Tsiamis,Peter Arensburger,Rita V. M. Rio,Sandy J. Macdonald,Sumir Panji,Sumir Panji,Adele Kruger,Alia Benkahla,Apollo Simon Peter Balyeidhusa,Atway R. Msangi,Chinyere K. Okoro,Dawn Stephens,Eleanor J Stanley,Feziwe Mpondo,Florence N. Wamwiri,Furaha Mramba,Geoffrey H. Siwo,George Githinji,Gordon William Harkins,Grace Murilla,Heikki Lehväslaiho,Imna I. Malele,Joanna E. Auma,Johnson Kinyua,Johnson O. Ouma,Loyce M. Okedi,Lucien Manga,Martin Aslett,Mathurin Koffi,Michael W. Gaunt,Mmule Makgamathe,Nicola Mulder,Oliver Manangwa,Patrick P. Abila,Patrick Wincker,Richard Gregory,Rosemary Bateta,Ryuichi Sakate,Sheila C. Ommeh,Stella Lehane,Tadashi Imanishi,Victor Chukwudi Osamor,Yoshihiro Kawahara,Yoshihiro Kawahara +147 more
TL;DR: The sequence and annotation of the 366-megabase Glossina mors Titans morsitans genome are described, providing a foundation for research into trypanosomiasis prevention and yield important insights with broad implications for multiple aspects of tsetse biology.
Journal ArticleDOI
The Dermis as a Delivery Site of Trypanosoma brucei for Tsetse Flies.
Guy Caljon,Guy Caljon,Nick Van Reet,Carl De Trez,Marjorie Vermeersch,David Perez-Morga,Jan Van Den Abbeele +6 more
TL;DR: Experimental transmission experiments combined with molecular parasite detection in blood fed flies provided evidence that dermal trypanosomes can be acquired from the inoculation site immediately after the initial transmission, and intradermal parasite expansion induces elevated skin surface temperatures.
Journal ArticleDOI
Trypanosoma brucei Modifies the Tsetse Salivary Composition, Altering the Fly Feeding Behavior That Favors Parasite Transmission
Jan Van Den Abbeele,Guy Caljon,Guy Caljon,Karin De Ridder,Patrick De Baetselier,Marc Coosemans +5 more
TL;DR: Evidence is provided for a trypanosome-mediated modification of the tsetse salivary composition that results in a drastically reduced anti-haemostatic potential and a hampered feeding performance which could lead to an increase of the vector/host contact and parasite transmission in field conditions.
Journal ArticleDOI
Immune Evasion Strategies of Trypanosoma brucei within the Mammalian Host: Progression to Pathogenicity
Benoit Stijlemans,Guy Caljon,Guy Caljon,Jan Van Den Abbeele,Jo A. Van Ginderachter,Stefan Magez,Carl De Trez +6 more
TL;DR: An overview of the different mechanisms AT (i.e. T. brucei as a model organism) employ, comprising both tsetse fly saliva and parasite-derived components to modulate host innate immune responses thereby sculpturing an environment that allows survival and development within the mammalian host.
Journal ArticleDOI
Genomic and Molecular Characterization of Miltefosine Resistance in Leishmania infantum Strains with Either Natural or Acquired Resistance through Experimental Selection of Intracellular Amastigotes.
Annelies Mondelaers,María P. Sánchez-Cañete,Sarah Hendrickx,Eline Eberhardt,Raquel García-Hernández,Laurence Lachaud,James Cotton,Mandy Sanders,Bart Cuypers,Hideo Imamura,Jean-Claude Dujardin,Peter Delputte,Paul Cos,Guy Caljon,Francisco Gamarro,Santiago Castanys,Louis Maes +16 more
TL;DR: A defective import machinery through inactivation of the LiMT/LiRos3 protein complex as the main mechanism for MIL-resistance also in intracellular amastigotes is confirmed and corroborate the pivotal role of theLiMT/ LiRos3 complex in resistance towards MIL.