S
Silvia Morbelli
Researcher at University of Genoa
Publications - 290
Citations - 7487
Silvia Morbelli is an academic researcher from University of Genoa. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 36, co-authored 245 publications receiving 5045 citations. Previous affiliations of Silvia Morbelli include National Cancer Research Institute & Health Science University.
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Journal ArticleDOI
Whitepaper: Defining and investigating cognitive reserve, brain reserve, and brain maintenance
Yaakov Stern,Eider M. Arenaza-Urquijo,David Bartrés-Faz,Sylvie Belleville,Marc Cantilon,Gaël Chételat,Michael Ewers,Nicolai Franzmeier,Gerd Kempermann,William S. Kremen,Ozioma C. Okonkwo,Nikolaos Scarmeas,Nikolaos Scarmeas,Anja Soldan,Chinedu T. Udeh-Momoh,Michael Valenzuela,Prashanthi Vemuri,Eero Vuoksimaa,Eider M. Arenaza Urquiljo,Marc Cantillon,Sean A. P. Clouston,Ainara Estanga,Brian T. Gold,Christian G. Habeck,Richard N. Jones,Renata Kochhann,W.S. Kremen,Yen Ying Lim,Pablo Martinez-Lage,Silvia Morbelli,Rik Ossenkoppele,Corinne Pettigrew,Allyson C. Rosen,Xiaowei Song,Anita C. van Loenhoud +34 more
TL;DR: The reserve, resilience, and protective factors professional interest area established a whitepaper workgroup to develop consensus definitions for cognitive reserve, brain reserve, and brain maintenance and evaluated measures that have been used to implement these concepts in research settings and developed guidelines for research that explores or utilizes these concepts.
Journal ArticleDOI
Risk and predictors of dementia and parkinsonism in idiopathic REM sleep behaviour disorder: a multicentre study
Ronald B. Postuma,Alex Iranzo,Michele T.M. Hu,Birgit Högl,Bradley F. Boeve,Raffaele Manni,Wolfgang H. Oertel,Isabelle Arnulf,Luigi Ferini-Strambi,Monica Puligheddu,Elena Antelmi,Valérie Cochen De Cock,Dario Arnaldi,Brit Mollenhauer,Aleksandar Videnovic,Karel Sonka,Ki-Young Jung,Dieter Kunz,Yves Dauvilliers,Federica Provini,Simon J.G. Lewis,Jitka Bušková,Milena Pavlova,Anna Heidbreder,Jacques Montplaisir,Joan Santamaria,Thomas R Barber,Ambra Stefani,Erik K. St. Louis,Michele Terzaghi,Annette Janzen,Smandra Leu-Semenescu,G. Plazzi,Flavio Nobili,Friederike Sixel-Doering,Petr Dusek,Frederik Bes,Pietro Cortelli,Kaylena A. Ehgoetz Martens,Jean-François Gagnon,Carles Gaig,Marco Zucconi,Claudia Trenkwalder,Ziv Gan-Or,Christine Lo,Michal Rolinski,Philip Mahlknecht,Evi Holzknecht,Angel R Boeve,Luke N. Teigen,Gianpaolo Toscano,Geert Mayer,Silvia Morbelli,Benjamin Dawson,Amélie Pelletier +54 more
TL;DR: In a prospective multicentre study involving 1280 patients with idiopathic RBD, Postuma et al. test the predictive power of 21 prodromal markers of neurodegeneration, providing a template for planning neuroprotective trials.
Journal ArticleDOI
Prevalence and prognosis of Alzheimer's disease at the mild cognitive impairment stage.
Stephanie J.B. Vos,Frans R.J. Verhey,Lutz Frölich,Johannes Kornhuber,Jens Wiltfang,Wolfgang Maier,Oliver Peters,Eckart Rüther,Flavio Nobili,Silvia Morbelli,Giovanni B. Frisoni,Alexander Drzezga,Mira Didic,Bart N.M. van Berckel,Andrew Simmons,Hilkka Soininen,Iwona Kłoszewska,Patrizia Mecocci,Magda Tsolaki,Bruno Vellas,Simon Lovestone,Cristina Muscio,Sanna-Kaisa Herukka,Eric Salmon,Christine Bastin,Anders Wallin,Arto Nordlund,Alexandre de Mendonça,Dina Silva,Isabel Santana,Raquel Lemos,Sebastiaan Engelborghs,Stefan Van der Mussele,Yvonne Freund-Levi,Åsa K. Wallin,Harald Hampel,Wiesje M. van der Flier,Philip Scheltens,Pieter Jelle Visser,Pieter Jelle Visser +39 more
TL;DR: The use of the proposed research criteria to identify Alzheimer's disease at the mild cognitive impairment stage and the use of both amyloid and neuronal injury markers as proposed by the National Institute of Ageing-Alzheimer Association criteria offers the most accurate prognosis are supported.
Journal ArticleDOI
Mesenchymal stem cells impair in vivo T-cell priming by dendritic cells
Sabrina Chiesa,Silvia Morbelli,Sara Morando,Michela Massollo,Cecilia Marini,Arinna Bertoni,Francesco Frassoni,Soraya Tabera Bartolomé,Gianmario Sambuceti,Elisabetta Traggiai,Antonio Uccelli +10 more
TL;DR: It is shown that murine MSC impair Toll-like receptor-4 induced activation of DC resulting in the inhibition of cytokines secretion, down-regulation of molecules involved in the migration to the lymph nodes, antigen presentation to CD4+ T cells, and cross-presentation to CD8+ T Cells.
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Amyloid-PET and 18F-FDG-PET in the diagnostic investigation of Alzheimer's disease and other dementias
Gaël Chételat,Javier Arbizu,Henryk Barthel,Valentina Garibotto,Ian Law,Silvia Morbelli,Elsmarieke van de Giessen,Federica Agosta,Frederik Barkhof,Frederik Barkhof,David J. Brooks,David J. Brooks,Maria C. Carrillo,Bruno Dubois,Anders M. Fjell,Anders M. Fjell,Giovanni B. Frisoni,Oskar Hansson,Karl Herholz,Brian Hutton,Clifford R. Jack,Adriaan A. Lammertsma,Susan M. Landau,Satoshi Minoshima,Flavio Nobili,Agneta Nordberg,Rik Ossenkoppele,Rik Ossenkoppele,Wim J.G. Oyen,Daniela Perani,Gil D. Rabinovici,Philip Scheltens,Victor L. Villemagne,Victor L. Villemagne,Henrik Zetterberg,Alexander Drzezga,Alexander Drzezga,Alexander Drzezga +37 more
TL;DR: A diagnostic algorithm with optimal timepoints for amyloid-PET and 18F-FDG-PET, taking into account evidence from other biomarkers, for early and differential diagnosis of neurodegenerative diseases that can lead to dementia is proposed.