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Suzanne Oparil

Researcher at University of Alabama at Birmingham

Publications -  941
Citations -  122414

Suzanne Oparil is an academic researcher from University of Alabama at Birmingham. The author has contributed to research in topics: Blood pressure & Angiotensin II. The author has an hindex of 106, co-authored 885 publications receiving 113983 citations. Previous affiliations of Suzanne Oparil include Michigan State University & Oregon Health & Science University.

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Journal ArticleDOI

Mibefradil, a T-Channel–Selective Calcium Antagonist Clinical Trials in Hypertension

Suzanne Oparil
- 01 Apr 1998 - 
TL;DR: Mibefradil, at the recommended doses of 50 to 100 mg/day, is safe and effective for the treatment of mild-to-moderate hypertension and was better tolerated than the comparison drugs.
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Salt supplementation does not alter the pressor effect of blocking atrial natriuretic peptide in nucleus tractus solitarii.

Renhui Yang, +4 more
- 01 Aug 1992 - 
TL;DR: Exogenous ANP in caudal nucleus tractus solitarii mediates tonic control of blood pressure in both salt-sensitive and salt-resistant SHR but not in Wistar-Kyoto rats, and this effect is independent of the salt sensitivity of hypertension and of dietary salt intake.
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Systolic blood pressure control prevents cognitive decline and slows development of white matter lesions in the brain: the SPRINT MIND study outcomes

Sverre E. Kjeldsen, +3 more
- 18 Oct 2019 - 
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Angiotensin receptor--neprilysin inhibiton (ARNI)--a novel therapeutic concept for management of hypertension and heart failure.

Sverre E. Kjeldsen, +3 more
- 04 Dec 2012 - 
TL;DR: The novel ARNI concept is currently being tested in a large outcomes trial in patients with heart failure with reduced ejection fraction and may also have potential therapeutic value in heart failure patients with preserved ejectedion fraction.
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The effects of urate lowering therapy on inflammation, endothelial function, and blood pressure (SURPHER) study design and rationale

Michael B. Saddekni, +13 more
- 01 Sep 2016 - 
TL;DR: The study aims to enroll otherwise healthy young adults for a pharmacological intervention study with multiple study-related procedures and mechanistic outcomes include changes in endothelial function as measured by flow-mediated dilation, as well as C-reactive protein levels.