S
Suzanne Oparil
Researcher at University of Alabama at Birmingham
Publications - 941
Citations - 122414
Suzanne Oparil is an academic researcher from University of Alabama at Birmingham. The author has contributed to research in topics: Blood pressure & Angiotensin II. The author has an hindex of 106, co-authored 885 publications receiving 113983 citations. Previous affiliations of Suzanne Oparil include Michigan State University & Oregon Health & Science University.
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Hypoxia-responsive growth factors upregulate periostin and osteopontin expression via distinct signaling pathways in rat pulmonary arterial smooth muscle cells.
TL;DR: This study is the first to demonstrate that growth factor-induced expression of PN in PASMCs is mediated through PI3K/p70S6K, Ras/MEK1/2, and Ras/p38MAPK signaling pathways, whereas the expression of OPN ismediated through Ras/meK1-2 and Ras-JNK signaling pathways.
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Sexually dimorphic response of the balloon-injured rat carotid artery to hormone treatment.
TL;DR: Intact male rats but not intact females are resistant to the vasoprotective effects of exogenous estrogen, despite attainment of physiological levels of serum 17 beta-estradiol levels.
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Salt Intake and Plasma Atrial Natriuretic Peptide and Nitric Oxide in Hypertension
Vito M. Campese,Medhat Tawadrous,Roberto Bigazzi,Stefano Bianchi,Amardeep S. Mann,Suzanne Oparil,Leopoldo Raij +6 more
TL;DR: The hypothesis that salt sensitivity depends on a deficit of nitric oxide production is not supported, but it suggests that high salt intake may alter the endothelium-dependent adaptation of peripheral resistance vessels.
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Effect of Intensive Versus Standard Blood Pressure Lowering on Diastolic Function in Patients With Uncontrolled Hypertension and Diastolic Dysfunction
Scott D. Solomon,Anil Verma,Akshay S. Desai,Amira H Hassanein,Joseph L. Izzo,Suzanne Oparil,Yves Lacourcière,Joleen Lee,Yodit Seifu,Robert Hilkert,Ricardo Rocha,Bertram Pitt +11 more
TL;DR: The degree of improvement in annular relaxation velocity was associated with the extent of systolic blood pressure reduction, and patients with the lowest achieved systolics blood pressure had the highest final diastolic relaxation velocities.
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Thiazide-induced dysglycemia: Call for research from a working group from the national heart, lung, and blood institute
Barry L. Carter,Paula T. Einhorn,Michael W. Brands,Jiang He,Jeffrey A. Cutler,Paul K. Whelton,George L. Bakris,Frederick L. Brancati,William C. Cushman,Suzanne Oparil,Jackson T. Wright +10 more
TL;DR: The ongoing success of thiazide-type diuretics in large, adequately powered hypertension outcome trials and new guidelines have created the basis for increased diuretic use.