S
Suzanne Oparil
Researcher at University of Alabama at Birmingham
Publications - 941
Citations - 122414
Suzanne Oparil is an academic researcher from University of Alabama at Birmingham. The author has contributed to research in topics: Blood pressure & Angiotensin II. The author has an hindex of 106, co-authored 885 publications receiving 113983 citations. Previous affiliations of Suzanne Oparil include Michigan State University & Oregon Health & Science University.
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Estrogen and Mechanisms of Vascular Protection
TL;DR: Cellular/molecular mechanisms by which estrogen modulates injury-induced inflammation, growth factor expression, and oxidative stress in arteries and isolated vascular smooth muscle cells are reviewed, with emphasis on the role of estrogen receptors and the nuclear factor-kappaB (NFkappa B) signaling pathway.
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The renin-angiotensin system (first of two parts).
Suzanne Oparil,Edgar Haber +1 more
TL;DR: The role of the kidney in blood-pressure regulation was established by TIGERSTEDT and Bergman at the close of the 19th century as discussed by the authors, who produced hypertension in dogs by injecting a cr...
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Characterization of Resistant Hypertension : Association Between Resistant Hypertension, Aldosterone, and Persistent Intravascular Volume Expansion
Krishna K. Gaddam,Mari Nishizaka,Monique N. Pratt-Ubunama,Eduardo Pimenta,Inmaculada Aban,Suzanne Oparil,David A. Calhoun +6 more
TL;DR: A significant correlation between 24-hour urinary ald testosterone levels and cortisol excretion suggests that a common stimulus, such as corticotropin, may underlie the aldosterone excess in patients with resistant hypertension.
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Direct in vivo evidence demonstrating neointimal migration of adventitial fibroblasts after balloon injury of rat carotid arteries
TL;DR: These observations provide direct demonstration of adventitial fibroblast migration into neointima of arteries after endoluminal injury.
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Association of Intensive vs Standard Blood Pressure Control With Cerebral White Matter Lesions.
Ilya M. Nasrallah,Nicholas M. Pajewski,Alexander P. Auchus,Gordon J. Chelune,Alfred K. Cheung,Maryjo Cleveland,Laura H. Coker,Michael Crowe,William C. Cushman,Jeffrey A. Cutler,Christos Davatzikos,Lisa Desiderio,Jimit Doshi,Guray Erus,Larry J. Fine,Sarah A. Gaussoin,Darrin Harris,Karen C. Johnson,Paul L. Kimmel,Manjula Kurella Tamura,Lenore J. Launer,Alan J. Lerner,Cora E. Lewis,Jennifer Martindale-Adams,Claudia S. Moy,Linda O. Nichols,Suzanne Oparil,Paula Ogrocki,Mahboob Rahman,Stephen R. Rapp,David M. Reboussin,Michael V. Rocco,Bonnie C. Sachs,Kaycee M. Sink,Kaycee M. Sink,Carolyn H Still,Mark A. Supiano,Joni K. Snyder,Virginia G. Wadley,Jennifer Walker,Daniel E. Weiner,Paul K. Whelton,Valerie M. Wilson,Nancy Woolard,Jackson T. Wright,Clinton B. Wright,Jeff D. Williamson,R. Nick Bryan +47 more
TL;DR: Among hypertensive adults, targeting an SBP of less than 120 mm HG, compared with less than 140 mm Hg, was significantly associated with a smaller increase in cerebral white matter lesion volume and a greater decrease in total brain volume, although the differences were small.