S
Suzanne Oparil
Researcher at University of Alabama at Birmingham
Publications - 941
Citations - 122414
Suzanne Oparil is an academic researcher from University of Alabama at Birmingham. The author has contributed to research in topics: Blood pressure & Angiotensin II. The author has an hindex of 106, co-authored 885 publications receiving 113983 citations. Previous affiliations of Suzanne Oparil include Michigan State University & Oregon Health & Science University.
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Advanced Glycation End-Product Cross-Link Breakers
George L. Bakris,Alan J. Bank,David A. Kass,Joel M. Neutel,Richard A. Preston,Suzanne Oparil +5 more
TL;DR: Alagebrium is the first drug in a new class of thiazolium therapeutic agents that break established AGE cross-links between proteins and was effective in improving cardiac function and uncontrolled systolic blood pressure, particularly in more severely affected patients.
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Stroke outcomes among participants randomized to chlorthalidone, amlodipine or lisinopril in ALLHAT
Jose-Miguel Yamal,Suzanne Oparil,Barry R. Davis,Michael H. Alderman,David A. Calhoun,William C. Cushman,Herbert F. Fendley,Stanley S. Franklin,Gabriel B. Habib,Sara L. Pressel,Jeffrey L. Probstfield,Sithiporn Sastrasinh +11 more
TL;DR: The AllHAT trial as mentioned in this paper compared cardiovascular disease outcomes in participants initially treated with an angiotensin-converting enzyme inhibitor (lisinopril), a calcium channel blocker (amlodipine), or a thiazide-type diuretic (chlorthalidone), for a total follow-up of 8-13 years.
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Acute Saline Infusion Decreases Norepinephrine Release in the Anterior Hypothalamic Area
TL;DR: A small elevation in plasma Na+ can reduce the release of norepinephrine in the anterior hypothalamic area and contribute to the rise in arterial pressure in spontaneously hypertensive rats ingesting a high NaCl diet.
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Renal Catecholamines and α2-Adrenergic Receptors in Salt-Related and Genetic Hypertension
Ralph Dawson,Suzanne Oparil +1 more
TL;DR: These studies demonstrated a relationship between renal NE content and renal α2-adrenergic receptors and the implications of this relationship and other salt-related changes in renal catecholamine metabolism were discussed as they pertained to hypertension and renal function.
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Correlations of plasma renin activity and aldosterone concentration with ambulatory blood pressure responses to nebivolol and valsartan, alone and in combination, in hypertension
Thomas D. Giles,George L. Bakris,Suzanne Oparil,Michael A. Weber,Huiling Li,Madhuja Mallick,David B. Bharucha,Chun Lin Chen,William G. Ferguson,John Sorin,Matthew Davis,Joesph Izzo,Nabile Andrawis,Alyn Anderson,Rogelio Bardinas-Rodriguez,Douglas Young,Andrew Schreiber,Cristian Breton,Duane Harris,Phillip LaStella,Ramon Castello,Susan Hole,Joesph Lillo,Luis Carlos Quintero,Carlos Montenegro,Jeffrey Rosen,Farid Marquez,Fredric Adler,Sady Alpizar,James Andersen,Corey Anderson,Graciela Calatayud,Kevin Cannon,Deanna Cheung,Rafel Chiong,Lisa Cohen,Harry Collins,Michael Dao,Cara H. Dawson,Donna DeSantis,Shelly Dunmyer,Sherif El-Harazi,Cecil M. Farrington,David Ferrera,Gregory S. Funk,Gregory Gottschlich,Terence T. Hart,Marvin Kalafer,Dean Kereiakes,Gigi Lefebvre,Aristolis Laliotis,Peter Mattar,Michael McCartney,Diane McConnehey,Curtis Mello,Joel Neutel,Deborah A. Burke,James Pritchard,George Raad,Bruce Rankin,John “Chip” H. Reed,Erich Schramm,Howard Schwartz,Nathan Segall,James Shoemaker,Vakas Sial,Teresa Sligh,William B. Smith,Richard Stewart,Dan Streja,Danny Sugimoto,Alexander White,Hayes Williams,William Abraham,Azazuddin Ahmed,Richard Beasley,Daniel Gruener,Connie Hsu,Ryan Klein,Allen Soo,Charles P. Andrews,Clinton Corder,Donald Hurley,Elizabeth Bretton,Richard Martinez,David Morin,Miguel Trevino,Samir Arora,Curtis Scott Horn,Charles Lovell,Thomas Nussdorfer,Robert Weiss,Harold Bays,Jackson Rhudy,Edwardo Almaguer,Joseph H. Woolley,Vicki Miller,Jaynier Moya-Hechevarria,Henry Punzi,Addison A. Taylor,Jonathan Wilson,Arnold Alper,Patricia Buchanan,Richard Dobrusin,Alan Forker,Razmig Krumian,Samuel F. Oberstein,Andrew Lewin,Mary Bella Natividad,Armando Segui,Wayne Harper,Andrea Lawless,Lawrence S. Levinson,Shaukat Shah,Loray Blair-Britt,Patrick Carmichael,Nathaniel Winer,David Grant,Kyle Rickner,Absalom Tilley,Linda Harper,Stephen Maddock,Joseph A. Boscia,Yekaterina Khronusova,Larry D. Reed,Chandar Abboy +125 more
TL;DR: The effects of this treatment on the renin-angiotensin-aldosterone system in a substudy are reported, with baseline ln(aldosterone) correlated with 24-hour systolic and diastolic BP reductions following combination treatment only.