S
Suzanne Oparil
Researcher at University of Alabama at Birmingham
Publications - 941
Citations - 122414
Suzanne Oparil is an academic researcher from University of Alabama at Birmingham. The author has contributed to research in topics: Blood pressure & Angiotensin II. The author has an hindex of 106, co-authored 885 publications receiving 113983 citations. Previous affiliations of Suzanne Oparil include Michigan State University & Oregon Health & Science University.
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Anterior hypothalamic norepinephrine, atrial natriuretic peptide, and hypertension.
TL;DR: Exogenous ANP in the brain is functionally active in the tonic control of blood pressure and baroreflex sensitivity in the SHR-S but plays a lesser role in the normotensive Wistar Kyoto control.
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Mechanisms and treatment of resistant hypertension.
TL;DR: Hyperaldosteronism is now recognized as the most common cause of resistant hypertension, and all patients with resistant hypertension should be screened with a plasma aldosterone/renin ratio even if the serum potassium level is normal.
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Randomized Study of Antihypertensive Efficacy and Safety of Combination Aliskiren/Valsartan vs Valsartan Monotherapy in Hypertensive Participants With Type 2 Diabetes Mellitus
TL;DR: Combination aliskiren/valsartan has additive effects on blood pressure reduction and tolerability similar to valsartan in hypertensive/diabetic participants with early‐stage CKD.
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Dose-response characteristics of mibefradil, a novel calcium antagonist, in the treatment of essential hypertension.
Suzanne Oparil,Isaac Kobrin,Darrell R. Abernethy,Barton S Levine,Max C Reif,Alexander M. M. Shepherd +5 more
TL;DR: The antihypertensive effect of mibefradil was associated with a slight dose-dependent decrease in heart rate and increase in the pulse rate (PR) electrocardiographic interval [corrected], and the appropriate therapeutic dose range of mibiafradil in the management of mild-to-moderate essential hypertension is 50 to 100 mg.
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Altered angiotensin-converting enzyme in lung and extrapulmonary tissues of hypoxia-adapted rats
TL;DR: The effects of chronic hypoxia on catalytically active ACE and ACE active sites in the intact animal were organ specific and Adaptation to chronic Hypoxia did not significantly alter plasma renin activity or ANG I or ANG II levels or serum ACE content.