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Suzanne Oparil

Researcher at University of Alabama at Birmingham

Publications -  941
Citations -  122414

Suzanne Oparil is an academic researcher from University of Alabama at Birmingham. The author has contributed to research in topics: Blood pressure & Angiotensin II. The author has an hindex of 106, co-authored 885 publications receiving 113983 citations. Previous affiliations of Suzanne Oparil include Michigan State University & Oregon Health & Science University.

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O-Linked β-N-Acetylglucosamine Modification of A20 Enhances the Inhibition of NF-κB (Nuclear Factor-κB) Activation and Elicits Vascular Protection After Acute Endoluminal Arterial Injury.

TL;DR: Results suggest that O-GlcNAcylation of A20 plays a key role in the negative regulation of NF-&kgr;B signaling cascades in TNF-&agr;–treated vascular smooth muscle cells in culture and in acutely injured arteries, thus protecting against inflammation-induced vascular injury.
Journal Article

Oral contraceptive pill hypertension.

TL;DR: Good results have been reported in those women taking OCs from the middle range, and possible risk factors increasing hypertensive susceptibility include genetic character istics preexisting and occult renal disease age and weight and possibl e antececent eclampsia.
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Proteoglycans and hypertension. I. A biochemical and ultrastructural study of aorta glycosaminoglycans in spontaneously hypertensive rats.

TL;DR: Analyzing the polysaccharide components of proteoglycans from aorta of two normotensive rat strains and from spontaneously hypertensive rats suggests that, if similar alterations in CS proteoglyCans are present in the resistance vessels, these changes may contribute to the increased peripheral vascular resistance in the hypertensive animal.
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Simplified method for quantitation of angiotensin peptides in tissue.

TL;DR: Radioimmunoassay of relevant peaks revealed detectable levels of angiotensin I-, II- and III-like immunoactivity in single rat hypothalami and brain stems.