S
Suzanne Oparil
Researcher at University of Alabama at Birmingham
Publications - 941
Citations - 122414
Suzanne Oparil is an academic researcher from University of Alabama at Birmingham. The author has contributed to research in topics: Blood pressure & Angiotensin II. The author has an hindex of 106, co-authored 885 publications receiving 113983 citations. Previous affiliations of Suzanne Oparil include Michigan State University & Oregon Health & Science University.
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Endothelin-A Receptor Blockade Prevents and Partially Reverses Neonatal Hypoxic Pulmonary Vascular Remodeling
TL;DR: Data show that in the newborn mouse model, chronic hypoxia leads to HPVR that can be completely prevented and partially reversed by ETA blockade, and indicate that ET-1, acting via ETA receptors, is a mechanism of pathophysiologic significance underlying neonatal HPVR.
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Pressor effect of blocking atrial natriuretic peptide in nucleus tractus solitarii.
TL;DR: It is suggested that endogenous atrial natriuretic peptide in the caudal nucleus tractus solitarii mediates tonic control of blood pressure in spontaneously hypertensive rats but not in normotensive Wistar-Kyoto rats.
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Low sodium intake--cardiovascular health benefit or risk?
TL;DR: Reducing dietary sodium and, to a lesser extent, increasing dietary potassium have been included in many guidelines for the treatment of hypertension and have been recommended in population-wide approaches to reducing blood pressure and therefore the burden of cardiovascular disease.
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Clinical Significance of Incident Hypokalemia and Hyperkalemia in Treated Hypertensive Patients in the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial
Michael H. Alderman,Linda B. Piller,Charles E. Ford,Jeffrey L. Probstfield,Suzanne Oparil,William C. Cushman,Paula T. Einhorn,Stanley S. Franklin,Vasilios Papademetriou,Stephen T. Ong,John H. Eckfeldt,Curt D. Furberg,David A. Calhoun,Barry R. Davis +13 more
TL;DR: For most patients, concerns about potassium levels should not influence the clinician's decision about initiating hypertension treatment with low-moderate doses of thiazide diuretics, and the uncommon appearance of hyperkalemia was associated with increased cardiovascular disease risk.
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Facts and fallacies of blood pressure control in recent trials: implications in the management of patients with hypertension.
Alberto Zanchetti,Giuseppe Mancia,Henry R. Black,Suzanne Oparil,Bernard Waeber,Roland E. Schmieder,George L. Bakris,Franz H. Messerli,Sverre E. Kjeldsen,Luis M. Ruilope +9 more
TL;DR: It is concluded that their complex design precludes a simple interpretation, that several important questions remain unanswered and that direct evidence – particularly in support of lowering systolic BP below 140 or 130 mmHg – is urgently needed.