V
Valeria Novelli
Researcher at Catholic University of the Sacred Heart
Publications - 37
Citations - 2530
Valeria Novelli is an academic researcher from Catholic University of the Sacred Heart. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 18, co-authored 29 publications receiving 1972 citations. Previous affiliations of Valeria Novelli include Joslin Diabetes Center & Agostino Gemelli University Polyclinic.
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Journal ArticleDOI
Missense Mutations in Plakophilin-2 Cause Sodium Current Deficit and Associate With a Brugada Syndrome Phenotype
Marina Cerrone,Xianming Lin,Mingliang Zhang,Esperanza Agullo-Pascual,Anna Pfenniger,Halina Chkourko Gusky,Valeria Novelli,Changsung Kim,Tiara Tirasawadichai,Daniel P. Judge,Eli Rothenberg,Huei Sheng Vincent Chen,Carlo Napolitano,Silvia G. Priori,Mario Delmar +14 more
TL;DR: This is the first systematic retrospective analysis of a patient group to define the coexistence of sodium channelopathy and genetic PKP2 variations and may be a molecular substrate leading to the diagnosis of BrS.
Journal ArticleDOI
Association of the FOXO3A Locus with Extreme Longevity in a Southern Italian Centenarian Study
Chiara Viviani Anselmi,Alberto Malovini,Roberta Roncarati,Valeria Novelli,Francesco Villa,Gianluigi Condorelli,Riccardo Bellazzi,Annibale Alessandro Puca +7 more
TL;DR: The data point to a key role of FOXO3A in human longevity and confirm the feasibility of the identification of such genes with centenarian-controls studies and hypothesize the susceptibility to the longevity phenotype may well be the result of complex interactions involving genes and environmental factors but also gender.
Journal ArticleDOI
Frontotemporal dementia and its subtypes: a genome-wide association study
Raffaele Ferrari,Raffaele Ferrari,Dena G. Hernandez,Dena G. Hernandez,Mike A. Nalls,Jonathan D. Rohrer,Adaikalavan Ramasamy,Adaikalavan Ramasamy,John B.J. Kwok,John B.J. Kwok,Carol Dobson-Stone,Carol Dobson-Stone,William S. Brooks,William S. Brooks,Peter R. Schofield,Peter R. Schofield,Glenda M. Halliday,Glenda M. Halliday,John R. Hodges,John R. Hodges,Olivier Piguet,Olivier Piguet,Lauren Bartley,Elizabeth Thompson,Elizabeth Thompson,Eric Haan,Eric Haan,Isabel Hernández,Agustín Ruiz,Mercè Boada,Barbara Borroni,Alessandro Padovani,Carlos Cruchaga,Nigel J. Cairns,Luisa Benussi,Giuliano Binetti,Roberta Ghidoni,Gianluigi Forloni,Daniela Galimberti,Chiara Fenoglio,Maria Serpente,Elio Scarpini,Jordi Clarimón,Alberto Lleó,Rafael Blesa,Maria Landqvist Waldö,Karin Nilsson,Christer Nilsson,Ian R. A. Mackenzie,Ging-Yuek Robin Hsiung,David M. A. Mann,Jordan Grafman,Jordan Grafman,Jordan Grafman,Christopher Morris,Johannes Attems,Timothy D. Griffiths,Ian G. McKeith,Alan J. Thomas,Pietro Pietrini,Edward D. Huey,Eric M. Wassermann,Atik Baborie,Evelyn Jaros,Evelyn Jaros,Michael Tierney,Pau Pastor,Cristina Razquin,Sara Ortega-Cubero,Elena Alonso,Robert Perneczky,Robert Perneczky,Janine Diehl-Schmid,Panagiotis Alexopoulos,Alexander Kurz,Innocenzo Rainero,Elisa Rubino,Lorenzo Pinessi,Ekaterina Rogaeva,Peter St George-Hyslop,Peter St George-Hyslop,Giacomina Rossi,Fabrizio Tagliavini,Giorgio Giaccone,James B. Rowe,James B. Rowe,Johannes C. M. Schlachetzki,Johannes C. M. Schlachetzki,James Uphill,John Collinge,Simon Mead,Adrian Danek,Adrian Danek,Vivianna M. Van Deerlin,Murray Grossman,John Q. Trojanowski,Julie van der Zee,William Deschamps,Tim Van Langenhove,Marc Cruts,Christine Van Broeckhoven,Stefano F. Cappa,Isabelle Le Ber,Didier Hannequin,Véronique Golfier,Martine Vercelletto,Alexis Brice,Benedetta Nacmias,Sandro Sorbi,Silvia Bagnoli,Irene Piaceri,Jørgen E. Nielsen,Jørgen E. Nielsen,Lena E. Hjermind,Lena E. Hjermind,Matthias Riemenschneider,Manuel Mayhaus,Bernd Ibach,Gilles Gasparoni,Sabrina Pichler,Wei Gu,Wei Gu,Martin N. Rossor,Nick C. Fox,Jason D. Warren,Maria Grazia Spillantini,Huw R. Morris,Patrizia Rizzu,Peter Heutink,Julie S. Snowden,Sara Rollinson,Anna Richardson,Alexander Gerhard,Amalia C. Bruni,Raffaele Maletta,Francesca Frangipane,Chiara Cupidi,Livia Bernardi,Maria Anfossi,Maura Gallo,Maria Elena Conidi,Nicoletta Smirne,Rosa Rademakers,Matthew C. Baker,Dennis W. Dickson,Neill R. Graff-Radford,Ronald C. Petersen,David S. Knopman,Keith A. Josephs,Bradley F. Boeve,Joseph E. Parisi,William W. Seeley,Bruce L. Miller,Anna Karydas,Howard J. Rosen,John C. van Swieten,John C. van Swieten,Elise G.P. Dopper,Harro Seelaar,Yolande A.L. Pijnenburg,Philip Scheltens,Giancarlo Logroscino,Rosa Capozzo,Valeria Novelli,Annibale Alessandro Puca,Massimo Franceschi,Alfredo Postiglione,Graziella Milan,Paolo Sorrentino,Mark Kristiansen,Huei-Hsin Chiang,Caroline Graff,Florence Pasquier,Adeline Rollin,Vincent Deramecourt,Florence Lebert,Dimitrios Kapogiannis,Luigi Ferrucci,Stuart Pickering-Brown,Andrew B. Singleton,John Hardy,Parastoo Momeni +181 more
TL;DR: The findings suggest that immune system processes (link to 6p21.3) and possibly lysosomal and autophagy pathways ( link to 11q14) are potentially involved in FTD.
Journal ArticleDOI
Reappraisal of Reported Genes for Sudden Arrhythmic Death: Evidence-Based Evaluation of Gene Validity for Brugada Syndrome.
S. Mohsen Hosseini,Raymond H. Kim,Sharmila Udupa,Gregory Costain,Rebekah Jobling,Eriskay Liston,Seema M. Jamal,Marta Szybowska,Chantal F. Morel,Sarah Bowdin,John Garcia,Melanie Care,Amy C. Sturm,Valeria Novelli,Michael J. Ackerman,James S. Ware,Ray E. Hershberger,Arthur A.M. Wilde,Michael H. Gollob +18 more
TL;DR: The results contest the clinical validity of all but 1 gene clinically tested and reported to be associated with BrS, and warrant a systematic, evidence-based evaluation for reported gene-disease associations before use in patient care.
Journal ArticleDOI
An International, Multicentered, Evidence-Based Reappraisal of Genes Reported to Cause Congenital Long QT Syndrome
Arnon Adler,Valeria Novelli,Ahmad S. Amin,Emanuela Abiusi,Melanie Care,Eline A. Nannenberg,Harriet Feilotter,Simona Amenta,Daniela Mazza,Hennie Bikker,Amy C. Sturm,John Garcia,Michael J. Ackerman,Raymond E. Hershberger,Marco V Perez,Wojciech Zareba,James S. Ware,James S. Ware,Arthur A.M. Wilde,Arthur A.M. Wilde,Michael H. Gollob +20 more
TL;DR: More than half of the genes reported as causing LQTS have limited or disputed evidence to support their disease causation, and genetic variants in these genes should not be used for clinical decision-making, unless accompanied by new and sufficient genetic evidence.