ETH Zurich

About: ETH Zurich is a education organization based out in Zurich, Switzerland. It is known for research contribution in the topics: Population & Computer science. The organization has 48393 authors who have published 122408 publications receiving 5111383 citations. The organization is also known as: Swiss Federal Institute of Technology in Zurich & Eidgenössische Technische Hochschule Zürich.

Ultraviolet Luminosity Functions from 132 z ~ 7 and z ~ 8 Lyman-break Galaxies in the Ultra-deep HUDF09 and Wide-area Early Release Science WFC3/IR Observations

Abstract: We identify 73 z ~ 7 and 59 z ~ 8 candidate galaxies in the reionization epoch, and use this large 26-29.4?AB?mag sample of galaxies to derive very deep luminosity functions to < ? 18?AB?mag and the star formation rate (SFR) density at z ~ 7 and z ~ 8 (just 800?Myr and 650?Myr after recombination, respectively). The galaxy sample is derived using a sophisticated Lyman-break technique on the full two-year Wide Field Camera 3/infrared (WFC3/IR) and Advanced Camera for Surveys (ACS) data available over the HUDF09 (~29.4?AB?mag, 5?), two nearby HUDF09 fields (~29?AB?mag, 5?, 14?arcmin2), and the wider area Early Release Science (~27.5?AB?mag, 5?, ~40?arcmin2). The application of strict optical non-detection criteria ensures the contamination fraction is kept low (just ~7% in the HUDF). This very low value includes a full assessment of the contamination from lower redshift sources, photometric scatter, active galactic nuclei, spurious sources, low-mass stars, and transients (e.g., supernovae). From careful modeling of the selection volumes for each of our search fields, we derive luminosity functions for galaxies at z ~ 7 and z ~ 8 to < ? 18?AB?mag. The faint-end slopes ? at z ~ 7 and z ~ 8 are uncertain but very steep at ? = ?2.01 ? 0.21 and ? = ?1.91 ? 0.32, respectively. Such steep slopes contrast to the local ? ?1.4 and may even be steeper than that at z ~ 4 where ? = ?1.73 ? 0.05. With such steep slopes (? ?1.7) lower luminosity galaxies dominate the galaxy luminosity density during the epoch of reionization. The SFR densities derived from these new z ~ 7 and z ~ 8 luminosity functions are consistent with the trends found at later times (lower redshifts). We find reasonable consistency with the SFR densities implied from reported stellar mass densities being only ~40% higher at z < 7. This suggests that (1) the stellar mass densities inferred from the Spitzer Infrared Array Camera (IRAC) photometry are reasonably accurate and (2) that the initial mass function at very high redshift may not be very different from that at later times.

Structural and functional characterization of two alpha-synuclein strains

Abstract: α-Synuclein aggregation is implicated in a variety of diseases including Parkinson's disease, dementia with Lewy bodies, pure autonomic failure and multiple system atrophy. The association of protein aggregates made of a single protein with a variety of clinical phenotypes has been explained for prion diseases by the existence of different strains that propagate through the infection pathway. Here we structurally and functionally characterize two polymorphs of α-synuclein. We present evidence that the two forms indeed fulfil the molecular criteria to be identified as two strains of α-synuclein. Specifically, we show that the two strains have different structures, levels of toxicity, and in vitro and in vivo seeding and propagation properties. Such strain differences may account for differences in disease progression in different individuals/cell types and/or types of synucleinopathies.

An AdS_3 Dual for Minimal Model CFTs

Abstract: We propose a duality between the 2d ${\mathcal{W}}_{N}$ minimal models in the large $N$ 't Hooft limit, and a family of higher spin theories on ${\mathrm{AdS}}_{3}$. The 2d conformal field theories (CFTs) can be described as Wess-Zumino-Witten coset models, and include, for $N=2$, the usual Virasoro unitary series. The dual bulk theory contains, in addition to the massless higher spin fields, two complex scalars (of equal mass). The mass is directly related to the 't Hooft coupling constant of the dual CFT. We give convincing evidence that the spectra of the two theories match precisely for all values of the 't Hooft coupling. We also show that the renormalization group flows in the 2d CFT agree exactly with the usual AdS/CFT prediction of the gravity theory. Our proposal is in many ways analogous to the Klebanov-Polyakov conjecture for an ${\mathrm{AdS}}_{4}$ dual for the singlet sector of large $N$ vector models.

Event generator tunes obtained from underlying event and multiparton scattering measurements

Abstract: New sets of parameters ("tunes") for the underlying-event (UE) modeling of the PYTHIA8, PYTHIA6 and HERWIG++ Monte Carlo event generators are constructed using different parton distribution functions. Combined fits to CMS UE data at sqrt(s) = 7 TeV and to UE data from the CDF experiment at lower sqrt(s), are used to study the UE models and constrain their parameters, providing thereby improved predictions for proton-proton collisions at 13 TeV. In addition, it is investigated whether the values of the parameters obtained from fits to UE observables are consistent with the values determined from fitting observables sensitive to double-parton scattering processes. Finally, comparisons of the UE tunes to "minimum bias" (MB) events, multijet, and Drell-Yan (q q-bar to Z / gamma* to lepton-antilepton + jets) observables at 7 and 8 TeV are presented, as well as predictions of MB and UE observables at 13 TeV.

Deterministic Coupling of Single Quantum Dots to Single Nanocavity Modes

Abstract: We demonstrate a deterministic approach to the implementation of solid-state cavity quantum electrodynamics (QED) systems based on a precise spatial and spectral overlap between a single self-assembled quantum dot and a photonic crystal membrane nanocavity. By fine-tuning nanocavity modes with a high quality factor into resonance with any given quantum dot exciton, we observed clear signatures of cavity QED (such as the Purcell effect) in all fabricated structures. This approach removes the major hindrances that had limited the application of solid-state cavity QED and enables the realization of experiments previously proposed in the context of quantum information processing.