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Institution

ETH Zurich

EducationZurich, Switzerland
About: ETH Zurich is a education organization based out in Zurich, Switzerland. It is known for research contribution in the topics: Population & Computer science. The organization has 48393 authors who have published 122408 publications receiving 5111383 citations. The organization is also known as: Swiss Federal Institute of Technology in Zurich & Eidgenössische Technische Hochschule Zürich.


Papers
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Journal ArticleDOI
29 Sep 2016-Nature
TL;DR: A global map of abundant, double-stranded DNA viruses complete with genomic and ecological contexts is presented to present a necessary foundation for the meaningful integration of viruses into ecosystem models where they act as key players in nutrient cycling and trophic networks.
Abstract: Ocean microbes drive biogeochemical cycling on a global scale. However, this cycling is constrained by viruses that affect community composition, metabolic activity, and evolutionary trajectories. Owing to challenges with the sampling and cultivation of viruses, genome-level viral diversity remains poorly described and grossly understudied, with less than 1% of observed surface-ocean viruses known. Here we assemble complete genomes and large genomic fragments from both surface- and deep-ocean viruses sampled during the Tara Oceans and Malaspina research expeditions, and analyse the resulting 'global ocean virome' dataset to present a global map of abundant, double-stranded DNA viruses complete with genomic and ecological contexts. A total of 15,222 epipelagic and mesopelagic viral populations were identified, comprising 867 viral clusters (defined as approximately genus-level groups). This roughly triples the number of known ocean viral populations and doubles the number of candidate bacterial and archaeal virus genera, providing a near-complete sampling of epipelagic communities at both the population and viral-cluster level. We found that 38 of the 867 viral clusters were locally or globally abundant, together accounting for nearly half of the viral populations in any global ocean virome sample. While two-thirds of these clusters represent newly described viruses lacking any cultivated representative, most could be computationally linked to dominant, ecologically relevant microbial hosts. Moreover, we identified 243 viral-encoded auxiliary metabolic genes, of which only 95 were previously known. Deeper analyses of four of these auxiliary metabolic genes (dsrC, soxYZ, P-II (also known as glnB) and amoC) revealed that abundant viruses may directly manipulate sulfur and nitrogen cycling throughout the epipelagic ocean. This viral catalog and functional analyses provide a necessary foundation for the meaningful integration of viruses into ecosystem models where they act as key players in nutrient cycling and trophic networks.

557 citations

Journal ArticleDOI
11 Aug 2017-Science
TL;DR: Analysis of the timing of river floods in Europe over the past 50 years found clear patterns of changes in flood timing that can be ascribed to climate effects, and highlights the existence of a clear climate signal in flood observations at the continental scale.
Abstract: A warming climate is expected to have an impact on the magnitude and timing of river floods; however, no consistent large-scale climate change signal in observed flood magnitudes has been identified so far. We analyzed the timing of river floods in Europe over the past five decades, using a pan-European database from 4262 observational hydrometric stations, and found clear patterns of change in flood timing. Warmer temperatures have led to earlier spring snowmelt floods throughout northeastern Europe; delayed winter storms associated with polar warming have led to later winter floods around the North Sea and some sectors of the Mediterranean coast; and earlier soil moisture maxima have led to earlier winter floods in western Europe. Our results highlight the existence of a clear climate signal in flood observations at the continental scale.

557 citations

Journal ArticleDOI
TL;DR: It is concluded that the control strategy has a significant impact on the resonance of the MC input filter.
Abstract: This paper presents a review of the most popular control and modulation strategies studied for matrix converters (MCs) in the last decade. The purpose of most of these methods is to generate sinusoidal current on the input and output sides. These methods are compared considering theoretical complexity and performance. This paper concludes that the control strategy has a significant impact on the resonance of the MC input filter.

556 citations

Journal ArticleDOI
TL;DR: In this article, the idea of a topological charge pump with topologically protected transport has been realized with ultracold bosonic atoms, where the quantized motion of charge due to the slow cyclic variation of a periodic potential has been quantized.
Abstract: Thouless introduced the idea of a topological charge pump: the quantized motion of charge due to the slow cyclic variation of a periodic potential. This topologically protected transport has now been realized with ultracold bosonic atoms.

556 citations

Journal ArticleDOI
01 Nov 2009
TL;DR: In this paper, the authors compare three promising methods of microrobot swimming (using magnetic fields to rotate helical propellers that mimic bacterial flagella, using magnetic forces to oscillate a magnetic head with a rigidly attached elastic tail, and pulling directly with magnetic field gradients) considering practical hardware limitations in the generation of magnetic fields.
Abstract: Microrobots have the potential to dramatically change many aspects of medicine by navigating through bodily fluids to perform targeted diagnosis and therapy. Researchers have proposed numerous micro-robotic swimming methods, with the vast majority utilizing magnetic fields to wirelessly power and control the microrobot. In this paper, we compare three promising methods of microrobot swimming (using magnetic fields to rotate helical propellers that mimic bacterial flagella, using magnetic fields to oscillate a magnetic head with a rigidly attached elastic tail, and pulling directly with magnetic field gradients) considering practical hardware limitations in the generation of magnetic fields. We find that helical propellers and elastic tails have very comparable performance, and they generally become more desirable than gradient pulling as size decreases and as distance from the magnetic-field-generation source increases. We provide a discussion of why helical propellers are likely the best overall choice for in vivo applications.

556 citations


Authors

Showing all 49062 results

NameH-indexPapersCitations
Ralph Weissleder1841160142508
Ruedi Aebersold182879141881
David L. Kaplan1771944146082
Andrea Bocci1722402176461
Richard H. Friend1691182140032
Lorenzo Bianchini1521516106970
David D'Enterria1501592116210
Andreas Pfeiffer1491756131080
Bernhard Schölkopf1481092149492
Martin J. Blaser147820104104
Sebastian Thrun14643498124
Antonio Lanzavecchia145408100065
Christoph Grab1441359144174
Kurt Wüthrich143739103253
Maurizio Pierini1431782104406
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023700
20221,316
20218,530
20208,660
20197,883
20187,455