Institution
Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto
Education•
About: Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto is a based out in . It is known for research contribution in the topics: Population & Catalysis. The organization has 2143 authors who have published 3674 publications receiving 71071 citations. The organization is also known as: FFCLRP & FFCLRP-USP.
Topics: Population, Catalysis, Gene, Genus, Ruthenium
Papers published on a yearly basis
Papers
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TL;DR: The filamentous fungus Aspergillus caespitosus was a good producer of intracellular and extracellular invertases under submerged (SbmF) or solid-state fermentation (SSF), using agroindustrial residues, such as wheat bran, as carbon source.
60 citations
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TL;DR: A Eurasian origin of Zanthoxylum in the Paleocene or Eocene with successive intercontinental or long-range migrations is revealed and the Hawaiian clade shows phylogenetic incongruence between the plastid and nuclear datasets, suggesting hybridization.
60 citations
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TL;DR: It is proposed that anxiolytic-sensitive freezing and fear-potentiated startle are triggered by moderate contextual fear conditioning, while contextual conditioning with the use of high footshocks causes a distinct pattern of behavioral responses, which is only partially affected by midazolam.
60 citations
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TL;DR: Novel drugs arising from the identification and analysis of bioactive peptides from South American anuran biodiversity have a promising future role on nanobiotechnology.
Abstract: Screening for new bioactive peptides in South American anurans has been pioneered in frogs of the genus Phyllomedusa. All frogs of this genus have venomous skin secretions, i.e., a complex mixture of bioactive peptides against potential predators and pathogens that presumably evolved in a scenario of predator–prey interaction and defense against microbial invasion. For every new anuran species studied new peptides are found, with homologies to hormones, neurotransmitters, antimicrobials, and several other peptides with unknown biological activity. From Vittorio Erspamer findings, this genus has been reported as a “treasure store” of bioactive peptides, and several groups focus their research on these species. From 1966 to 2009, more than 200 peptide sequences from different Phyllomedusa species were deposited in UniProt and other databases. During the last decade, the emergence of high-throughput molecular technologies involving de novo peptide sequencing via tandem mass spectrometry, cDNA cloning, pharmacological screening, and surface plasmon resonance applied to peptide discovery, led to fast structural data acquisition and the generation of peptide molecular libraries. Research groups on bioactive peptides in Brazil using these new technologies, accounted for the exponential increase of new molecules described in the last decade, much higher than in any previous decades. Recently, these secretions were also reported as a rich source of multiple antimicrobial peptides effective against multidrug resistant strains of bacteria, fungi, protozoa, and virus, providing instructive lessons for the development of new and more efficient nanotechnological-based therapies for infectious diseases treatment. Therefore, novel drugs arising from the identification and analysis of bioactive peptides from South American anuran biodiversity have a promising future role on nanobiotechnology.
60 citations
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TL;DR: NRC-loaded lipid carriers were developed and characterized to further explore its topical administration for applications such as skin cancer treatment and performed well enough at releasing and protecting NO degradation in vitro that it is a promising carrier for topical delivery of NO.
60 citations
Authors
Showing all 2195 results
Name | H-index | Papers | Citations |
---|---|---|---|
Jon Lloyd | 80 | 230 | 30995 |
Peter C. Ford | 74 | 495 | 20821 |
Frederico Guilherme Graeff | 60 | 183 | 12209 |
Marcus Lira Brandão | 54 | 243 | 9248 |
David W. Roubik | 54 | 177 | 10070 |
Richard J. Ward | 53 | 242 | 9502 |
Juan Cornejo | 49 | 147 | 6478 |
Norberto Peporine Lopes | 47 | 457 | 12031 |
Carlos Alemán | 47 | 634 | 11349 |
Klaus Hartfelder | 45 | 150 | 7708 |
Valtencir Zucolotto | 45 | 212 | 6253 |
Rosane Marina Peralta | 44 | 212 | 5701 |
Antonio Claudio Tedesco | 44 | 307 | 6778 |
Roberto M. Torresi | 44 | 213 | 5822 |
Zilá Luz Paulino Simões | 43 | 113 | 8020 |