Institution
Ghent University
Education•Ghent, Belgium•
About: Ghent University is a education organization based out in Ghent, Belgium. It is known for research contribution in the topics: Population & Context (language use). The organization has 36170 authors who have published 111042 publications receiving 3774501 citations. The organization is also known as: UGent & University of Ghent.
Papers published on a yearly basis
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TL;DR: The European Cancer Anaemia Survey (ECAS) was conducted to prospectively evaluate the prevalence, incidence and treatment of anaemia in European cancer patients, including the relationship of mild, moderate and severe anaemia to performance status.
760 citations
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TL;DR: Evidence indicates that motor competence is positively associated with perceived competence and multiple aspects of health, but questions related to the increased strength of associations across time and antecedent/consequent mechanisms remain.
Abstract: In 2008, Stodden and colleagues took a unique developmental approach toward addressing the potential role of motor competence in promoting positive or negative trajectories of physical activity, health-related fitness, and weight status. The conceptual model proposed synergistic relationships among physical activity, motor competence, perceived motor competence, health-related physical fitness, and obesity with associations hypothesized to strengthen over time. At the time the model was proposed, limited evidence was available to support or refute the model hypotheses. Over the past 6 years, the number of investigations exploring these relationships has increased significantly. Thus, it is an appropriate time to examine published data that directly or indirectly relate to specific pathways noted in the conceptual model. Evidence indicates that motor competence is positively associated with perceived competence and multiple aspects of health (i.e., physical activity, cardiorespiratory fitness, muscular strength, muscular endurance, and a healthy weight status). However, questions related to the increased strength of associations across time and antecedent/consequent mechanisms remain. An individual’s physical and psychological development is a complex and multifaceted process that synergistically evolves across time. Understanding the most salient factors that influence health and well-being and how relationships among these factors change across time is a critical need for future research in this area. This knowledge could aid in addressing the declining levels of physical activity and fitness along with the increasing rates of obesity across childhood and adolescence.
759 citations
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Vienna University of Technology1, Centre national de la recherche scientifique2, European Centre for Medium-Range Weather Forecasts3, National Research Council4, ETH Zurich5, Finnish Meteorological Institute6, Nanjing University of Information Science and Technology7, Ghent University8, VU University Amsterdam9, Starlab10, University College Cork11
TL;DR: The European Space Agency (ESA) released the first multi-decadal, global satellite-observed soil moisture (SM) dataset as part of its Climate Change Initiative (CCI) program.
756 citations
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TL;DR: Insight is provided into the endogenous immune system of the central nervous system during development, homeostasis and disease, and may also provide new targets for the treatment of neurodegenerative and neuroinflammatory pathologies.
Abstract: Microglia have critical roles not only in neural development and homeostasis, but also in neurodegenerative and neuroinflammatory diseases of the central nervous system1-4. These highly diverse and specialized functions may be executed by subsets of microglia that already exist in situ, or by specific subsets of microglia that develop from a homogeneous pool of cells on demand. However, little is known about the presence of spatially and temporally restricted subclasses of microglia in the central nervous system during development or disease. Here we combine massively parallel single-cell analysis, single-molecule fluorescence in situ hybridization, advanced immunohistochemistry and computational modelling to comprehensively characterize subclasses of microglia in multiple regions of the central nervous system during development and disease. Single-cell analysis of tissues of the central nervous system during homeostasis in mice revealed specific time- and region-dependent subtypes of microglia. Demyelinating and neurodegenerative diseases evoked context-dependent subtypes of microglia with distinct molecular hallmarks and diverse cellular kinetics. Corresponding clusters of microglia were also identified in healthy human brains, and the brains of patients with multiple sclerosis. Our data provide insights into the endogenous immune system of the central nervous system during development, homeostasis and disease, and may also provide new targets for the treatment of neurodegenerative and neuroinflammatory pathologies.
755 citations
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Newcastle University1, J. Craig Venter Institute2, University of Maryland, College Park3, University of Glasgow4, Technical University of Denmark5, University of Calgary6, Natural History Museum7, Ghent University8, University of Dundee9, University of Sassari10, University of California, Los Angeles11, Children's Hospital Oakland Research Institute12, Charles University in Prague13, University of Iowa14, University of Düsseldorf15, University of California, San Francisco16, University of Queensland17, QIMR Berghofer Medical Research Institute18, Chang Gung University19, University of Strathclyde20
TL;DR: The genome sequence of the protist Trichomonas vaginalis predicts previously unknown functions for the hydrogenosome, which support a common evolutionary origin of this unusual organelle with mitochondria.
Abstract: We describe the genome sequence of the protist Trichomonas vaginalis, a sexually transmitted human pathogen. Repeats and transposable elements comprise about two-thirds of the similar to 160-megabase genome, reflecting a recent massive expansion of genetic material. This expansion, in conjunction with the shaping of metabolic pathways that likely transpired through lateral gene transfer from bacteria, and amplification of specific gene families implicated in pathogenesis and phagocytosis of host proteins may exemplify adaptations of the parasite during its transition to a urogenital environment. The genome sequence predicts previously unknown functions for the hydrogenosome, which support a common evolutionary origin of this unusual organelle with mitochondria.
751 citations
Authors
Showing all 36585 results
Name | H-index | Papers | Citations |
---|---|---|---|
Stephen V. Faraone | 188 | 1427 | 140298 |
Peter Carmeliet | 164 | 844 | 122918 |
Monique M.B. Breteler | 159 | 546 | 93762 |
Dirk Inzé | 149 | 647 | 74468 |
Rajesh Kumar | 149 | 4439 | 140830 |
Vishva M. Dixit | 145 | 355 | 96471 |
Ruth J. F. Loos | 142 | 647 | 92485 |
Martin Grunewald | 140 | 1575 | 126911 |
Willy Verstraete | 139 | 920 | 76659 |
Barbara Clerbaux | 138 | 1394 | 96447 |
Peter Vandenabeele | 135 | 729 | 81692 |
Michael Tytgat | 134 | 1449 | 94133 |
Pascal Vanlaer | 133 | 1270 | 91850 |
Filip Moortgat | 132 | 1118 | 97714 |
Emelia J. Benjamin | 131 | 640 | 99972 |