Radboud University Nijmegen

About: Radboud University Nijmegen is a education organization based out in Nijmegen, Gelderland, Netherlands. It is known for research contribution in the topics: Population & Context (language use). The organization has 35417 authors who have published 83035 publications receiving 3285064 citations. The organization is also known as: Catholic University of Nijmegen & Radboud University.

Predicting behavior from actions in the past : repeated decision making or a matter of habit?

Abstract: This paper summarizes research on determinants of repeated behaviors, and the decision processes underlying them. The present research focuses on travel mode choices as an example of such behaviors. It is proposed that when behavior is performed repeatedly and becomes habitual, it is guided by automated cognitive processes, rather than being preceded by elaborate decision processes (i.e., a decision based on attitudes and intentions). First, current attitude-behavior models are discussed, and the role of habit in these models is examined. Second, research is presented on the decision processes preceding travel mode choices. Based on the present theoretical and empirical overview, it is concluded that frequently performed behavior is often a matter of habit, thereby establishing a boundary condition for the applicability of attitude-behavior models. However, more systematic research is required to disentangle the role of habit in attitude-behavior models and to learn more about the cognitive processes underlying habitual behavior.

Caspofungin versus liposomal amphotericin B for empirical antifungal therapy in patients with persistent fever and neutropenia.

Abstract: Background Patients with persistent fever and neutropenia often receive empirical therapy with conventional or liposomal amphotericin B for the prevention and early treatment of invasive fungal infections. Caspofungin, a member of the new echinocandin class of compounds, may be an effective alternative that is better tolerated than amphotericin B. Methods In this randomized, double-blind, multinational trial, we assessed the efficacy and safety of caspofungin as compared with liposomal amphotericin B as empirical antifungal therapy. At study entry, patients were stratified according to risk and according to whether they had previously received antifungal prophylaxis. A successful outcome was defined as the fulfillment of all components of a five-part composite end point. Results Efficacy was evaluated in 1095 patients (556 receiving caspofungin and 539 receiving liposomal amphotericin B). After adjustment for strata, the overall success rates were 33.9 percent for caspofungin and 33.7 percent for liposoma...