Showing papers by "Université libre de Bruxelles published in 2022"

Narrowband Searches for Continuous and Long-duration Transient Gravitational Waves from Known Pulsars in the LIGO-Virgo Third Observing Run

Abstract: Isolated neutron stars that are asymmetric with respect to their spin axis are possible sources of detectable continuous gravitational waves. This paper presents a fully-coherent search for such signals from eighteen pulsars in data from LIGO and Virgo's third observing run (O3). For known pulsars, efficient and sensitive matched-filter searches can be carried out if one assumes the gravitational radiation is phase-locked to the electromagnetic emission. In the search presented here, we relax this assumption and allow the frequency and frequency time-derivative of the gravitational waves to vary in a small range around those inferred from electromagnetic observations. We find no evidence for continuous gravitational waves, and set upper limits on the strain amplitude for each target. These limits are more constraining for seven of the targets than the spin-down limit defined by ascribing all rotational energy loss to gravitational radiation. In an additional search we look in O3 data for long-duration (hours-months) transient gravitational waves in the aftermath of pulsar glitches for six targets with a total of nine glitches. We report two marginal outliers from this search, but find no clear evidence for such emission either. The resulting duration-dependent strain upper limits do not surpass indirect energy constraints for any of these targets.

Is high-speed rail socially exclusive? An evidence-based worldwide analysis

Abstract: The extent to which high-speed rail (HSR) could be socially egalitarian has been disregarded, despite evidence that upper social-occupational groups are the primary users of high-speed trains (HSTs). In this context, this review aims to fill the gap by investigating the social attributes of HSR passengers based on worldwide, available ex post data derived from surveys at both national and corridor levels. The study’s results converge to conclude that HSR passengers are predominantly male, higher income, highly educated and belonging to higher social-occupational groups. Key indicators of social inequalities (i.e. income, occupational group and education) show a much sharper differentiation in HSR use than gender and age. Social inequalities arguably shape the uneven use of HSR through available income compared to HSR fares; through income compared to total expenditure on non-business travel; and through travel purposes, considering the high share of business travel aboard HSTs. Our findings highlight “greener” transport means and policies may not be socially inclusive. They also raise the issue of facilities (co-)funded by taxpayers that do not benefit the masses.

Is high-speed rail socially exclusive? An evidence-based worldwide analysis

Abstract: The extent to which high-speed rail (HSR) could be socially egalitarian has been disregarded, despite evidence that upper social-occupational groups are the primary users of high-speed trains (HSTs). In this context, this review aims to fill the gap by investigating the social attributes of HSR passengers based on worldwide, available ex post data derived from surveys at both national and corridor levels. The study’s results converge to conclude that HSR passengers are predominantly male, higher income, highly educated and belonging to higher social-occupational groups. Key indicators of social inequalities (i.e. income, occupational group and education) show a much sharper differentiation in HSR use than gender and age. Social inequalities arguably shape the uneven use of HSR through available income compared to HSR fares; through income compared to total expenditure on non-business travel; and through travel purposes, considering the high share of business travel aboard HSTs. Our findings highlight “greener” transport means and policies may not be socially inclusive. They also raise the issue of facilities (co-)funded by taxpayers that do not benefit the masses.

Improved global-scale predictions of soil carbon stocks with Millennial Version 2

Abstract: Soil carbon (C) models are used to predict C sequestration responses to climate and land use change. Yet, the soil models embedded in Earth system models typically do not represent processes that reflect our current understanding of soil C cycling, such as microbial decomposition, mineral association, and aggregation. Rather, they rely on conceptual pools with turnover times that are fit to bulk C stocks and/or fluxes. As measurements of soil fractions become increasingly available, it is necessary for soil C models to represent these measurable quantities so that model processes can be evaluated more accurately. Here we present Version 2 (V2) of the Millennial model, a soil model developed to simulate C pools that can be measured by extraction or fractionation, including particulate organic C, mineral-associated organic C, aggregate C, microbial biomass, and low molecular weight C. Model processes have been updated to reflect the current understanding of mineral-association, temperature sensitivity and reaction kinetics, and different model structures were tested within an open-source framework. We evaluated the ability of Millennial V2 to simulate total soil organic C (SOC), as well as the mineral-associated and particulate fractions, using three independent data sets of soil fractionation measurements spanning a range of climate and geochemistry in Australia (N = 495), Europe (N = 175), and across the globe (N = 659). When using all the data together (N = 1329), the Millennial V2 model predicted SOC (RMSE = 3.3 kg C m−2, AIC = 675, R i n 2 = 0.31, R o u t 2 = 0.26) better than the widely-used first-order decomposition model Century (RMSE = 3.4 kg C m−2, AIC = 696, R i n 2 = 0.21, R o u t 2 = 0.18) across sites, despite the fact that Millennial V2 has an increase in process complexity and number of parameters compared to Century. Millennial V2 also reproduced the observed fraction of C in MAOM and larger particle size fractions for most latitudes and biomes, and allows for a more detailed understanding of the pools and processes that affect model performance. It is important to note that this study evaluates the spatial variation in C stock only, and that the temporal dynamics of Millennial V2 remain to be tested. The Millennial V2 model updates the conceptual Century model pools and processes and represents our current understanding of the roles that microbial activity, mineral association and aggregation play in soil C sequestration.

Future water temperature of rivers in Switzerland under climate change investigated with physics-based models

Abstract: Abstract. River ecosystems are highly sensitive to climate change and projected future increase in air temperature is expected to increase the stress for these ecosystems. Rivers are also an important socio-economic factor impacting, amongst others, agriculture, tourism, electricity production, and drinking water supply and quality. In addition to changes in water availability, climate change will impact river temperature. This study presents a detailed analysis of river temperature and discharge evolution over the 21st century in Switzerland. In total, 12 catchments are studied, situated both on the lowland Swiss Plateau and in the Alpine regions. The impact of climate change is assessed using a chain of physics-based models forced with the most recent climate change scenarios for Switzerland including low-, mid-, and high-emission pathways. The suitability of such models is discussed in detail and recommendations for future improvements are provided. The model chain is shown to provide robust results, while remaining limitations are identified. These are mechanisms missing in the model to correctly simulate water temperature in Alpine catchments during the summer season. A clear warming of river water is modelled during the 21st century. At the end of the century (2080–2090), the median annual river temperature increase ranges between +0.9 ∘C for low-emission and +3.5 ∘C for high-emission scenarios for both lowland and Alpine catchments. At the seasonal scale, the warming on the lowland and in the Alpine regions exhibits different patterns. For the lowland the summer warming is stronger than the one in winter but is still moderate. In Alpine catchments, only a very limited warming is expected in winter. The period of maximum discharge in Alpine catchments, currently occurring during mid-summer, will shift to earlier in the year by a few weeks (low emission) or almost 2 months (high emission) by the end of the century. In addition, a noticeable soil warming is expected in Alpine regions due to glacier and snow cover decrease. All results of this study are provided with the corresponding source code used for this paper.

Console-Based Mapping of Mongolia Using GMT Cartographic Scripting Toolset for Processing TerraClimate Data

Abstract: This paper explores spatial variability of the ten climatic variables of Mongolia in 2019: average minimal and maximal temperatures, wind speed, soil moisture, downward surface shortwave radiation (DSRAD), snow water equivalent (SWE), vapor pressure deficit (VPD), vapor pressure anomaly (VAP), monthly precipitation and Palmer Drought Severity Index (PDSI). The PDSI demonstrates the simplified soil water balance estimating relative soil moisture conditions in Mongolia. The research presents mapping of the climate datasets derived from TerraClimate open source repository of the meteorological and climate measurements in NetCDF format. The methodology presented the compiled observations of Mongolia visualised by GMT coding approach using Generic Mapping Tools (GMT) cartographic scripting toolset. The results present 10 new maps of climate data over Mongolia made using automated cartographic techniques of GMT. Spatial environmental and climate analysis were conducted which determine relative distribution of PDSI and temperature extremes, precipitation and soil moisture, wind speed and DSRAD. The DSRAD showed minimum at 40 Wm−2, maximum at 113 Wm−2 in the Gobi Desert region, SWE (up to 491 mm), VAP and VPD compared with landmass parameters represent powerful cartographic tools to address complex regional climate and environmental issues in Mongolia, a country with contrasting topography, extreme climate conditions and unique environmental setting.

Testing super heavy dark matter from primordial black holes with gravitational waves

Abstract: Abstract Ultra-light primordial black holes with masses M BH < 10 9 g evaporate before big-bang nucleosynthesis producing all matter fields, including dark matter, in particular super-heavy dark matter: M DM ≳ 10 10 GeV. If the dark matter gets its mass via U(1) symmetry-breaking, the phase transition that gives a mass to the dark matter also produces cosmic strings which radiate gravitational waves. Because the symmetry-breaking scale Λ CS is of the same order as M DM , the gravitational waves radiated by the cosmic strings have a large enough amplitude to be detectable across all frequencies accessible with current and planned experimental facilities. Moreover, an epoch of early primordial black hole domination introduces a unique spectral break in the gravitational wave spectrum whose frequency is related to the super-heavy dark matter mass. Hence, the features of a stochastic background of primordial gravitational waves could indicate that super-heavy dark matter originated from primordial black holes. In this perspective, the recent finding of a stochastic common-spectrum process across many pulsars by two nano-frequency pulsar timing arrays would fix the dark matter mass to be 3 × 10 13 GeV ≲ M DM ≲ 10 14 GeV. The (non-)detection of a spectral break at 0.2 Hz ≲ f * ≲ 0.4 Hz would (exclude) substantiate this interpretation of the signal.

Generalized semiconfined harmonic oscillator model with a position-dependent effective mass

Abstract: By using a point canonical transformation starting from the constant-mass Schr\"odinger equation for the isotonic potential, it is shown that a semiconfined harmonic oscillator model with a position-dependent mass in the BenDaniel-Duke setting and the same spectrum as the standard harmonic oscillator can be easily constructed and extended to a semiconfined shifted harmonic oscillator, which could result from the presence of a uniform gravitational field. A further generalization is proposed by considering a $m$-dependent position-dependent mass for $0

Simulation of organics in the atmosphere: evaluation of EMACv2.54 with the Mainz Organic Mechanism (MOM) coupled to the ORACLE (v1.0) submodel

Abstract: Abstract. An updated and expanded representation of organics in the chemistry general circulation model EMAC (ECHAM5/MESSy for Atmospheric Chemistry) has been evaluated. First, the comprehensive Mainz Organic Mechanism (MOM) in the submodel MECCA (Module Efficiently Calculating the Chemistry of the Atmosphere) was activated with explicit degradation of organic species up to five carbon atoms and a simplified mechanism for larger molecules. Second, the ORACLE submodel (version 1.0) now considers condensation on aerosols for all organics in the mechanism. Parameterizations for aerosol yields are used only for the lumped species that are not included in the explicit mechanism. The simultaneous usage of MOM and ORACLE allows an efficient estimation of not only the chemical degradation of the simulated volatile organic compounds but also the contribution of organics to the growth and fate of (organic) aerosol, with the complexity of the mechanism largely increased compared to EMAC simulations with more simplified chemistry. The model evaluation presented here reveals that the OH concentration is reproduced well globally, whereas significant biases for observed oxygenated organics are present. We also investigate the general properties of the aerosols and their composition, showing that the more sophisticated and process-oriented secondary aerosol formation does not degrade the good agreement of previous model configurations with observations at the surface, allowing further research in the field of gas–aerosol interactions.

Transplantable human thyroid organoids generated from embryonic stem cells to rescue hypothyroidism

Abstract: Abstract The thyroid gland captures iodide in order to synthesize hormones that act on almost all tissues and are essential for normal growth and metabolism. Low plasma levels of thyroid hormones lead to hypothyroidism, which is one of the most common disorder in humans and is not always satisfactorily treated by lifelong hormone replacement. Therefore, in addition to the lack of in vitro tractable models to study human thyroid development, differentiation and maturation, functional human thyroid organoids could pave the way to explore new therapeutic approaches. Here we report the generation of transplantable thyroid organoids derived from human embryonic stem cells capable of restoring plasma thyroid hormone in athyreotic mice as a proof of concept for future therapeutic development.

Exercise haemodynamics in heart failure with preserved ejection fraction: a systematic review and meta‐analysis

Abstract: Exercise right heart catheterization (RHC) is considered the gold-standard test to diagnose heart failure with preserved ejection fraction (HFpEF). However, exercise RHC is an insufficiently standardized technique, and current haemodynamic thresholds to define HFpEF are not universally accepted. We sought to describe the exercise haemodynamics profile of HFpEF cohorts reported in literature, as compared with control subjects.We performed a systematic literature review until December 2020. Studies reporting pulmonary artery wedge pressure (PAWP) at rest and peak exercise were extracted. Summary estimates of all haemodynamic variables were evaluated, stratified according to body position (supine/upright exercise). The PAWP/cardiac output (CO) slope during exercise was extrapolated. Twenty-seven studies were identified, providing data for 2180 HFpEF patients and 682 controls. At peak exercise, patients with HFpEF achieved higher PAWP (30 [29-31] vs. 16 [15-17] mmHg, P < 0.001) and mean right atrial pressure (P < 0.001) than controls. These differences persisted after adjustment for age, sex, body mass index, and body position. However, peak PAWP values were highly heterogeneous among the cohorts (I2 = 93%), with a relative overlap with controls. PAWP/CO slope was steeper in HFpEF than in controls (3.75 [3.20-4.28] vs. 0.95 [0.30-1.59] mmHg/L/min, P value < 0.0001), even after adjustment for covariates (P = 0.007).Despite methodological heterogeneity, as well as heterogeneity of pooled haemodynamic estimates, the exercise haemodynamic profile of HFpEF patients is consistent across studies and characterized by a steep PAWP rise during exercise. More standardization of exercise haemodynamics may be advisable for a wider application in clinical practice.

The effect of (and the potential of recycled) superabsorbent polymers on the water retention capability and bio-receptivity of cementitious materials

Abstract: The evolution of rural to urban areas has a negative impact on the availability of green zones. The lack of space gives green concrete walls the opportunity to introduce vegetated areas in highly urbanized cities. However, cementitious materials are not the best substrate for plants. Still, diverse microbial communities are suitable for colonizing cementitious materials, allowing later introduction of other plants. One of the limiting factors for microbial growth under environmental conditions is the availability of water for the microorganisms. In this study, the bio-receptivity of cementitious materials under laboratory conditions was investigated, studying relevant parameters such as the porosity needed for the colonisation. Superabsorbent polymers (SAPs) were added in order to improve the water retention capacity and the colonisation of cementitious materials. These polymers, crosslinked networks able to absorb fluids up to hundreds of times their own weight, promote bio-receptivity and clear algal growth was observed. Recycled SAPs, obtained from a cleaning and crushing action of hygienic products, may show an added benefit in terms of sustainability and a circular economy. The best results were obtained with a SAP leading to a well-distributed overall macroporosity near the surface.

Waste Apple Pomace Conversion to Acrylic Acid: Economic and Potential Environmental Impact Assessments

Abstract: The global demand for acrylic acid (AA) is increasing due to its wide range of applications. Due to this growing demand, alternative AA production strategies must be explored to avoid the exacerbation of prevailing climate and global warming issues since current AA production strategies involve fossil resources. Investigations regarding alternative strategies for AA production therefore constitute an important research interest. The present study assesses waste apple pomace (WAP) as a feedstock for sustainable AA production. To undertake this assessment, process models based on two production pathways were designed, modelled and simulated in ASPEN plus® software. The two competing production pathways investigated included a process incorporating WAP conversion to lactic acid (LA) prior to LA dehydration to generate AA (denoted as the fermentation–dehydration, i.e., FD, pathway) and another process involving WAP conversion to propylene prior to propylene oxidation to generate AA (denoted as the thermochemical–fermentation–oxidation, i.e., TFO, pathway). Economic performance and potential environmental impact of the FD and TFO pathways were assessed using the metrics of minimum selling price (MSP) and potential environmental impacts per h (PEI/h). The study showed that the FD pathway presented an improved economic performance (MSP of AA: USD 1.17 per kg) compared to the economic performance (MSP of AA: USD 1.56 per kg) of the TFO pathway. Crucially, the TFO process was determined to present an improved environmental performance (2.07 kPEI/h) compared to the environmental performance of the FD process (8.72 kPEI/h). These observations suggested that the selection of the preferred AA production pathway or process will require a tradeoff between economic and environmental performance measures via the integration of a multicriteria decision assessment in future work.

Rosacea, an infectious disease: why rosacea with papulopustules should be considered a demodicosis. A narrative review

Abstract: Rosacea and demodicosis are common facial conditions in dermatology practice. While demodicosis is clearly the result of Demodex mite infestation, the pathogenicity of rosacea is still not sufficiently explained, so that it is defined by its symptoms, and not by its cause. It is usually considered as a disease of the immune system associated with neurogenic inflammation triggered by various factors (ultraviolet light, heat, spicy food, alcohol, stress and microorganisms). Its links with demodicosis remain controversial, although there is increasing evidence that Demodex mites may play a key role in the inflammatory process. Indeed, high Demodex densities are observed in nearly all cases of rosacea with papulopustules (PPR) and the papulopustules of rosacea can be effectively treated with topical acaricidal agents. Recent studies suggest that Demodex induces two opposite actions on host immunity: a defensive immune response aimed at eliminating the mite and an immunosuppressive action aimed at favouring its own proliferation. Moreover, the initial defensive immune response is likely diverted towards benefit for the mite, via T-cell exhaustion induced by the immunosuppressive properties of vascular endothelial growth factor, which may also explain the favourable influence that the altered vascular background of rosacea seems to exert on Demodex proliferation. In this review, the evidence for and against a causal role of Demodex in rosacea is discussed, applying three systems traditionally used to attribute causality to a disease (modified Koch criteria, Hill criteria for causality and Rothman model). The findings suggest that PPR can reasonably be attributed to Demodex proliferation, which appears to be a necessary factor in the centre of a causal network in which multiple co-factors interact and influence the occurrence and severity of inflammatory symptoms, from limited (pityriasis folliculorum) to more marked (PPR). PPR could, therefore, be considered as a chronic infection by Demodex mites with associated T-cell exhaustion.