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Institution

University of Alberta

EducationEdmonton, Alberta, Canada
About: University of Alberta is a education organization based out in Edmonton, Alberta, Canada. It is known for research contribution in the topics: Population & Health care. The organization has 65403 authors who have published 154847 publications receiving 5358338 citations. The organization is also known as: Ualberta & UAlberta.


Papers
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Journal ArticleDOI
TL;DR: Using eight hypervariable microsatellite loci to study the genetic relationships between four Canadian polar bear populations indicates that gene flow between local populations is restricted despite the long‐distance seasonal movements undertaken by polar bears.
Abstract: Attempts to study the genetic population structure of large mammals are often hampered by the low levels of genetic variation observed in these species. Polar bears have particularly low levels of genetic variation with the result that their genetic population structure has been intractable. We describe the use of eight hypervariable microsatellite loci to study the genetic relationships between four Canadian polar bear populations: the northern Beaufort Sea, southern Beaufort Sea, western Hudson Bay, and Davis Strait-Labrador Sea. These markers detected considerable genetic variation, with average heterozygosity near 60% within each population. Interpopulation differences in allele frequency distribution were significant between all pairs of populations, including two adjacent populations in the Beaufort Sea. Measures of genetic distance reflect the geographic distribution of populations, but also suggest patterns of gene flow which are not obvious from geography and may reflect movement patterns of these animals. Distribution of variation is sufficiently different between the Beaufort Sea populations and the two more eastern ones that the region of origin for a given sample can be predicted based on its expected genotype frequency using an assignment test. These data indicate that gene flow between local populations is restricted despite the long-distance seasonal movements undertaken by polar bears.

1,985 citations

Book
16 Feb 2012
TL;DR: In this paper, the authors introduce the Institutional Logics Perspective and define the Inter-institutional System (IIS) as "the emergence, stability and change of the IIS system".
Abstract: 1. Introduction to the Institutional Logics Perspective 2. Precursors to the Institutional Logics Perspective 3. Defining the Inter-institutional System 4. The Emergence, Stability and Change of the Inter-institutional System 5. Micro-Foundations of Institutional Logics 6. The Dynamics of Organizational Practices and Identities 7. The Emergence and Evolution of Field-Level Logics 8. Implications for Future Research

1,983 citations

Journal ArticleDOI
22 Sep 2011-Nature
TL;DR: Target metagenomic analyses of rigorously authenticated ancient DNA from 30,000-year-old Beringian permafrost sediments are reported and show conclusively that antibiotic resistance is a natural phenomenon that predates the modern selective pressure of clinical antibiotic use.
Abstract: The discovery of antibiotics more than 70 years ago initiated a period of drug innovation and implementation in human and animal health and agriculture. These discoveries were tempered in all cases by the emergence of resistant microbes. This history has been interpreted to mean that antibiotic resistance in pathogenic bacteria is a modern phenomenon; this view is reinforced by the fact that collections of microbes that predate the antibiotic era are highly susceptible to antibiotics. Here we report targeted metagenomic analyses of rigorously authenticated ancient DNA from 30,000-year-old Beringian permafrost sediments and the identification of a highly diverse collection of genes encoding resistance to β-lactam, tetracycline and glycopeptide antibiotics. Structure and function studies on the complete vancomycin resistance element VanA confirmed its similarity to modern variants. These results show conclusively that antibiotic resistance is a natural phenomenon that predates the modern selective pressure of clinical antibiotic use.

1,973 citations

Journal ArticleDOI
TL;DR: In this article, an attempt is made to define a geomagnetic storm as an interval of time when a sufficiently intense and long-lasting interplanetary convection electric field leads, through a substantial energization in the magnetosphere-ionosphere system, to an intensified ring current sufficiently strong to exceed some key threshold of the quantifying storm time Dst index.
Abstract: After a brief review of magnetospheric and interplanetary phenomena for intervals with enhanced solar wind-magnetosphere interaction, an attempt is made to define a geomagnetic storm as an interval of time when a sufficiently intense and long-lasting interplanetary convection electric field leads, through a substantial energization in the magnetosphere-ionosphere system, to an intensified ring current sufficiently strong to exceed some key threshold of the quantifying storm time Dst index. The associated storm/substorm relationship problem is also reviewed. Although the physics of this relationship does not seem to be fully understood at this time, basic and fairly well established mechanisms of this relationship are presented and discussed. Finally, toward the advancement of geomagnetic storm research, some recommendations are given concerning future improvements in monitoring existing geomagnetic indices as well as the solar wind near Earth.

1,963 citations

Book
01 Jan 1993
TL;DR: The fifth edition of this leading text has been substantially revised to provide an up-to-date and comprehensive assessment of the nature, extent and dimensions of international population movements, as well as of their consequences.
Abstract: International migration is a central feature of the contemporary world. The fifth edition of this leading text has been substantially revised to provide an up-to-date and comprehensive assessment of the nature, extent and dimensions of international population movements, as well as of their consequences. Taking full account of the latest developments, including the impact of the global economic crisis and the relationship of globalization to migration, this text firmly contextualizes the main issues, theories and history that contribute to the field. This latest edition has extensive coverage of regional case studies, as well as additional material that examines the effect of climate change on migration. The book's companion website helps to consolidate learning by providing additional resources, including further case studies, links to external web-pages and a web-only chapter.

1,925 citations


Authors

Showing all 66027 results

NameH-indexPapersCitations
Salim Yusuf2311439252912
Yi Chen2174342293080
Robert M. Califf1961561167961
Douglas R. Green182661145944
Russel J. Reiter1691646121010
Jiawei Han1681233143427
Jaakko Kaprio1631532126320
Tobin J. Marks1591621111604
Josef M. Penninger154700107295
Subir Sarkar1491542144614
Gerald M. Edelman14754569091
Rinaldo Bellomo1471714120052
P. Sinervo138151699215
David A. Jackson136109568352
Andreas Warburton135157897496
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20241
2023234
20221,084
20219,315
20208,831
20198,177