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Institution

University of Alberta

EducationEdmonton, Alberta, Canada
About: University of Alberta is a education organization based out in Edmonton, Alberta, Canada. It is known for research contribution in the topics: Population & Health care. The organization has 65403 authors who have published 154847 publications receiving 5358338 citations. The organization is also known as: Ualberta & UAlberta.


Papers
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Journal ArticleDOI
TL;DR: Findings can guide efforts to preserve and promote child health during the COVID-19 outbreak and crisis recovery period, and to inform strategies to mitigate potential harm during future pandemics.
Abstract: Healthy childhood development is fostered through sufficient physical activity (PA; including time outdoors), limiting sedentary behaviours (SB), and adequate sleep; collectively known as movement behaviours. Though the COVID-19 virus outbreak has changed the daily lives of children and youth, it is unknown to what extent related restrictions may compromise the ability to play and meet movement behaviour recommendations. This secondary data analysis examined the immediate impacts of COVID-19 restrictions on movement and play behaviours in children and youth. A national sample of Canadian parents (n = 1472) of children (5–11 years) or youth (12–17 years) (54% girls) completed an online survey that assessed immediate changes in child movement and play behaviours during the COVID-19 outbreak. Behaviours included PA and play, SB, and sleep. Family demographics and parental factors that may influence movement behaviours were assessed. Correlations between behaviours and demographic and parental factors were determined. For open-ended questions, word frequency distributions were reported. Only 4.8% (2.8% girls, 6.5% boys) of children and 0.6% (0.8% girls, 0.5% boys) of youth were meeting combined movement behaviour guidelines during COVID-19 restrictions. Children and youth had lower PA levels, less outside time, higher SB (including leisure screen time), and more sleep during the outbreak. Parental encouragement and support, parental engagement in PA, and family dog ownership were positively associated with healthy movement behaviours. Although families spent less time in PA and more time in SB, several parents reported adopting new hobbies or accessing new resources. This study provides evidence of immediate collateral consequences of the COVID-19 outbreak, demonstrating an adverse impact on the movement and play behaviours of Canadian children and youth. These findings can guide efforts to preserve and promote child health during the COVID-19 outbreak and crisis recovery period, and to inform strategies to mitigate potential harm during future pandemics.

644 citations

Journal ArticleDOI
TL;DR: A literature review on recent applications and design aspects of the intelligent reflecting surface (IRS) in the future wireless networks, and the joint optimization of the IRS’s phase control and the transceivers’ transmission control in different network design problems, e.g., rate maximization and power minimization problems.
Abstract: This paper presents a literature review on recent applications and design aspects of the intelligent reflecting surface (IRS) in the future wireless networks. Conventionally, the network optimization has been limited to transmission control at two endpoints, i.e., end users and network controller. The fading wireless channel is uncontrollable and becomes one of the main limiting factors for performance improvement. The IRS is composed of a large array of scattering elements, which can be individually configured to generate additional phase shifts to the signal reflections. Hence, it can actively control the signal propagation properties in favor of signal reception, and thus realize the notion of a smart radio environment. As such, the IRS’s phase control, combined with the conventional transmission control, can potentially bring performance gain compared to wireless networks without IRS. In this survey, we first introduce basic concepts of the IRS and the realizations of its reconfigurability. Then, we focus on applications of the IRS in wireless communications. We overview different performance metrics and analytical approaches to characterize the performance improvement of IRS-assisted wireless networks. To exploit the performance gain, we discuss the joint optimization of the IRS’s phase control and the transceivers’ transmission control in different network design problems, e.g., rate maximization and power minimization problems. Furthermore, we extend the discussion of IRS-assisted wireless networks to some emerging use cases. Finally, we highlight important practical challenges and future research directions for realizing IRS-assisted wireless networks in beyond 5G communications.

642 citations

Journal ArticleDOI
TL;DR: In this paper, the authors examine the effects of storytelling on a firm's ability to secure capital and argue that narratives help leverage resources by conveying a comprehensible identity for an entrepreneurial firm, elaborating the logic behind proposed means of exploiting opportunities and embedding entrepreneurial endeavors within broader discourses.
Abstract: Adopting a narrative approach to resource acquisition research, we examine the effects of storytelling on a firm’s ability to secure capital. We argue that narratives help leverage resources by conveying a comprehensible identity for an entrepreneurial firm, elaborating the logic behind proposed means of exploiting opportunities and embedding entrepreneurial endeavors within broader discourses. Qualitative analyses of all 1996–2000 initial public offering prospectuses in three high-tech industries reveal how identity constructions, story elaboration, and contextual embedding are invoked within narratives. Our quantitative findings show how these aspects of an entrepreneurial narrative impact resource acquisition net of previously emphasized factors.

641 citations

Journal ArticleDOI
TL;DR: These consensus statements provide a review of the literature and specific, updated recommendations for eradication therapy in adults and recommend that all H pylori eradication regimens now be given for 14 days.

641 citations

Journal ArticleDOI
Ryan K. C. Yuen1, Daniele Merico1, Matt Bookman2, Jennifer L. Howe1, Bhooma Thiruvahindrapuram1, Rohan V. Patel1, Joe Whitney1, Nicole A. Deflaux2, Jonathan Bingham2, Zhuozhi Wang1, Giovanna Pellecchia1, Janet A. Buchanan1, Susan Walker1, Christian R. Marshall1, Mohammed Uddin1, Mehdi Zarrei1, Eric Deneault1, Lia D’Abate1, Lia D’Abate3, Ada J.S. Chan3, Ada J.S. Chan1, Stephanie Koyanagi1, Tara Paton1, Sergio L. Pereira1, Ny Hoang1, Worrawat Engchuan1, Edward J Higginbotham1, Karen Ho1, Sylvia Lamoureux1, Weili Li1, Jeffrey R. MacDonald1, Thomas Nalpathamkalam1, Wilson W L Sung1, Fiona Tsoi1, John Wei1, Lizhen Xu1, Anne Marie Tassé4, Emily Kirby4, William Van Etten, Simon N. Twigger, Wendy Roberts, Irene Drmic1, Sanne Jilderda1, Bonnie Mackinnon Modi1, Barbara Kellam1, Michael J. Szego3, Michael J. Szego1, Cheryl Cytrynbaum, Rosanna Weksberg3, Lonnie Zwaigenbaum5, Marc Woodbury-Smith1, Marc Woodbury-Smith6, Jessica Brian3, Lili Senman3, Alana Iaboni3, Krissy A.R. Doyle-Thomas3, Ann Thompson6, Christina Chrysler6, Jonathan Leef3, Tal Savion-Lemieux4, Isabel M. Smith7, Xudong Liu8, Rob Nicolson9, Vicki Seifer10, Angie Fedele10, Edwin H. Cook11, Stephen R. Dager12, Annette Estes12, Louise Gallagher13, Beth A. Malow14, Jeremy R. Parr15, Sarah J. Spence16, Jacob A. S. Vorstman17, Brendan J. Frey3, James T. Robinson18, Lisa J. Strug3, Lisa J. Strug1, Bridget A. Fernandez19, Mayada Elsabbagh4, Melissa T. Carter20, Joachim Hallmayer21, Bartha Maria Knoppers4, Evdokia Anagnostou3, Peter Szatmari3, Peter Szatmari22, Robert H. Ring23, David Glazer2, Mathew T. Pletcher10, Stephen W. Scherer3, Stephen W. Scherer1 
TL;DR: Se sequencing of 5,205 samples from families with ASD, accompanied by clinical information, creating a database accessible on a cloud platform and through a controlled-access internet portal that identified 18 new candidate ASD-risk genes and found that participants bearing mutations in susceptibility genes had significantly lower adaptive ability.
Abstract: We are performing whole-genome sequencing of families with autism spectrum disorder (ASD) to build a resource (MSSNG) for subcategorizing the phenotypes and underlying genetic factors involved. Here we report sequencing of 5,205 samples from families with ASD, accompanied by clinical information, creating a database accessible on a cloud platform and through a controlled-access internet portal. We found an average of 73.8 de novo single nucleotide variants and 12.6 de novo insertions and deletions or copy number variations per ASD subject. We identified 18 new candidate ASD-risk genes and found that participants bearing mutations in susceptibility genes had significantly lower adaptive ability (P = 6 × 10-4). In 294 of 2,620 (11.2%) of ASD cases, a molecular basis could be determined and 7.2% of these carried copy number variations and/or chromosomal abnormalities, emphasizing the importance of detecting all forms of genetic variation as diagnostic and therapeutic targets in ASD.

641 citations


Authors

Showing all 66027 results

NameH-indexPapersCitations
Salim Yusuf2311439252912
Yi Chen2174342293080
Robert M. Califf1961561167961
Douglas R. Green182661145944
Russel J. Reiter1691646121010
Jiawei Han1681233143427
Jaakko Kaprio1631532126320
Tobin J. Marks1591621111604
Josef M. Penninger154700107295
Subir Sarkar1491542144614
Gerald M. Edelman14754569091
Rinaldo Bellomo1471714120052
P. Sinervo138151699215
David A. Jackson136109568352
Andreas Warburton135157897496
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20241
2023234
20221,084
20219,315
20208,831
20198,177