Institution
University of Antwerp
Education•Antwerp, Belgium•
About: University of Antwerp is a education organization based out in Antwerp, Belgium. It is known for research contribution in the topics: Population & Context (language use). The organization has 16682 authors who have published 48837 publications receiving 1689748 citations. The organization is also known as: Universiteit Antwerpen & UAntwerp.
Papers published on a yearly basis
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Oregon State University1, University of Antwerp2, Seconda Università degli Studi di Napoli3, Max Planck Society4, University of New Hampshire5, Tuscia University6, University of Edinburgh7, University of Oxford8, University of Liège9, Dresden University of Technology10, University College Dublin11, Institut national de la recherche agronomique12, Tulane University13, University of Minnesota14, Pennsylvania State University15, VU University Amsterdam16, University of California, Irvine17, Swedish University of Agricultural Sciences18, Oak Ridge National Laboratory19, United States Department of Agriculture20, Harvard University21, University of Helsinki22, Wageningen University and Research Centre23, Lund University24, Finnish Meteorological Institute25, University of Lisbon26, University of Milan27, National Institute of Advanced Industrial Science and Technology28
TL;DR: In this article, the authors present a comprehensive global database for forest ecosystems, which includes carbon budget variables (fluxes and stocks), ecosystem traits (e.g., leaf area index, age), as well as ancillary site information such as management regime, climate, and soil characteristics.
Abstract: Terrestrial ecosystems sequester 2.1 Pg of atmospheric carbon annually. A large amount of the terrestrial sink is realized by forests. However, considerable uncertainties remain regarding the fate of this carbon over both short and long timescales. Relevant data to address these uncertainties are being collected at many sites around the world, but syntheses of these data are still sparse. To facilitate future synthesis activities, we have assembled a comprehensive global database for forest ecosystems, which includes carbon budget variables (fluxes and stocks), ecosystem traits (e.g. leaf area index, age), as well as ancillary site information such as management regime, climate, and soil characteristics. This publicly available database can be used to quantify global, regional or biome-specific carbon budgets; to re-examine established relationships; to test emerging hypotheses about ecosystem functioning [e.g. a constant net ecosystem production (NEP) to gross primary production (GPP) ratio]; and as benchmarks for model evaluations. In this paper, we present the first analysis of this database. We discuss the climatic influences on GPP, net primary production (NPP) and NEP and present the CO2 balances for boreal, temperate, and tropical forest biomes based on micrometeorological, ecophysiological, and biometric flux and inventory estimates. Globally, GPP of forests benefited from higher temperatures and precipitation whereas NPP saturated above either a threshold of 1500 mm precipitation or a mean annual temperature of 10 degrees C. The global pattern in NEP was insensitive to climate and is hypothesized to be mainly determined by nonclimatic conditions such as successional stage, management, site history, and site disturbance. In all biomes, closing the CO2 balance required the introduction of substantial biome-specific closure terms. Nonclosure was taken as an indication that respiratory processes, advection, and non-CO2 carbon fluxes are not presently being adequately accounted for.
938 citations
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TL;DR: The ROBPCA approach, which combines projection pursuit ideas with robust scatter matrix estimation, yields more accurate estimates at noncontaminated datasets and more robust estimates at contaminated data.
Abstract: We introduce a new method for robust principal component analysis (PCA). Classical PCA is based on the empirical covariance matrix of the data and hence is highly sensitive to outlying observations. Two robust approaches have been developed to date. The first approach is based on the eigenvectors of a robust scatter matrix such as the minimum covariance determinant or an S-estimator and is limited to relatively low-dimensional data. The second approach is based on projection pursuit and can handle high-dimensional data. Here we propose the ROBPCA approach, which combines projection pursuit ideas with robust scatter matrix estimation. ROBPCA yields more accurate estimates at noncontaminated datasets and more robust estimates at contaminated data. ROBPCA can be computed rapidly, and is able to detect exact-fit situations. As a by-product, ROBPCA produces a diagnostic plot that displays and classifies the outliers. We apply the algorithm to several datasets from chemometrics and engineering.
935 citations
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TL;DR: It is demonstrated that distinct α-SYN strains display differential seeding capacities, inducing strain-specific pathology and neurotoxic phenotypes, and α- SYN assemblies cross the blood–brain barrier and distribute to the central nervous system after intravenous injection.
Abstract: Misfolded protein aggregates represent a continuum with overlapping features in neurodegenerative diseases, but differences in protein components and affected brain regions. The molecular hallmark of synucleinopathies such as Parkinson's disease, dementia with Lewy bodies and multiple system atrophy are megadalton α-synuclein-rich deposits suggestive of one molecular event causing distinct disease phenotypes. Glial α-synuclein (α-SYN) filamentous deposits are prominent in multiple system atrophy and neuronal α-SYN inclusions are found in Parkinson's disease and dementia with Lewy bodies. The discovery of α-SYN assemblies with different structural characteristics or 'strains' has led to the hypothesis that strains could account for the different clinico-pathological traits within synucleinopathies. In this study we show that α-SYN strain conformation and seeding propensity lead to distinct histopathological and behavioural phenotypes. We assess the properties of structurally well-defined α-SYN assemblies (oligomers, ribbons and fibrils) after injection in rat brain. We prove that α-SYN strains amplify in vivo. Fibrils seem to be the major toxic strain, resulting in progressive motor impairment and cell death, whereas ribbons cause a distinct histopathological phenotype displaying Parkinson's disease and multiple system atrophy traits. Additionally, we show that α-SYN assemblies cross the blood-brain barrier and distribute to the central nervous system after intravenous injection. Our results demonstrate that distinct α-SYN strains display differential seeding capacities, inducing strain-specific pathology and neurotoxic phenotypes.
931 citations
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TL;DR: An overview of gas discharge plasmas can be found in this paper, where the most important applications of these and related plasmmas are discussed, as well as their working principles.
928 citations
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TL;DR: A review of currently available mass spectrometry methodology used in the structure elucidation of flavonoids is presented and sample preparation, liquid chromatographic/mass spectrometric analysis and tandem mass Spectrometric procedures for the characterization of flav onoid aglycones, O-glycosides, C-glyCosides and acylated glycosides are considered.
Abstract: Flavonoids are very common and widespread secondary plant metabolites. They have a wide range of biological and physiological activities and serve as chemotaxonomic marker compounds. Therefore, they have been extensively investigated both in the past and during recent years. The interest in them is still increasing. In the search for new compounds, and also in quality control, there is a need to have reliable methodology for the analysis of flavonoids. Mass spectrometry can make an invaluable contribution because of its high sensitivity, possibilities of coupling with liquid chromatography and the availability of powerful tandem mass spectrometric techniques. A review of currently available mass spectrometric methodology used in the structure elucidation of flavonoids is presented. Sample preparation, liquid chromatographic/mass spectrometric analysis and tandem mass spectrometric procedures for the characterization of flavonoid aglycones, O-glycosides, C-glycosides and acylated glycosides are considered.
907 citations
Authors
Showing all 16957 results
Name | H-index | Papers | Citations |
---|---|---|---|
Cornelia M. van Duijn | 183 | 1030 | 146009 |
John Hardy | 177 | 1178 | 171694 |
Mark Gerstein | 168 | 751 | 149578 |
Hannes Jung | 159 | 2069 | 125069 |
Rui Zhang | 151 | 2625 | 107917 |
Dirk Inzé | 149 | 647 | 74468 |
Walter Paulus | 149 | 809 | 86252 |
Robin Erbacher | 138 | 1721 | 100252 |
Rupert Leitner | 136 | 1201 | 90597 |
Alison Goate | 136 | 721 | 85846 |
Andrea Giammanco | 135 | 1362 | 98093 |
Maria Spiropulu | 135 | 1455 | 96674 |
Peter Robmann | 135 | 1438 | 97569 |
Michael Tytgat | 134 | 1449 | 94133 |
Matthew Herndon | 133 | 1732 | 97466 |