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Institution

University of Guelph

EducationGuelph, Ontario, Canada
About: University of Guelph is a education organization based out in Guelph, Ontario, Canada. It is known for research contribution in the topics: Population & Gene. The organization has 26542 authors who have published 50553 publications receiving 1715255 citations. The organization is also known as: U of G & Guelph University.


Papers
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Journal ArticleDOI
TL;DR: It is speculated that in obesity fatty acid transporters are relocated from an intracellular pool to the plasma membrane in heart, muscle, and adipose tissues.

274 citations

Journal ArticleDOI
TL;DR: HCH biodegradation in soil has been reported at both low and high (saturated) moisture contents, and soil texture and organic matter appear to influence degradation presumably by sorption mechanisms and impact on moisture retention, bacterial growth and pH.
Abstract: The organochlorine pesticide Lindane is the gamma-isomer of hexachlorocyclohexane (HCH). Technical grade Lindane contains a mixture of HCH isomers which include not only gamma-HCH, but also large amounts of predominantly alpha-, beta- and delta-HCH. The physical properties and persistence of each isomer differ because of the different chlorine atom orientations on each molecule (axial or equatorial). However, all four isomers are considered toxic and recalcitrant worldwide pollutants. Biodegradation of HCH has been studied in soil, slurry and culture media but very little information exists on in situ bioremediation of the different isomers including Lindane itself, at full scale. Several soil microorganisms capable of degrading, and utilizing HCH as a carbon source, have been reported. In selected bacterial strains, the genes encoding the enzymes involved in the initial degradation of Lindane have been cloned, sequenced, expressed and the gene products characterized. HCH is biodegradable under both oxic and anoxic conditions, although mineralization is generally observed only in oxic systems. As is found for most organic compounds, HCH degradation in soil occurs at moderate temperatures and at near neutral pH. HCH biodegradation in soil has been reported at both low and high (saturated) moisture contents. Soil texture and organic matter appear to influence degradation presumably by sorption mechanisms and impact on moisture retention, bacterial growth and pH. Most studies report on the biodegradation of relatively low (< 500 mg/kg) concentrations of HCH in soil. Information on the effects of inorganic nutrients, organic carbon sources or other soil amendments is scattered and inconclusive. More in-depth assessments of amendment effects and evaluation of bioremediation protocols, on a large scale, using soil with high HCH concentrations, are needed.

273 citations

Journal ArticleDOI
TL;DR: A systematic investigation of the notion of Bregman monotonicity leads to a simplified analysis of numerous algorithms and to the development of a new class of parallel block-iterative surrogate BRegman projection schemes.
Abstract: A broad class of optimization algorithms based on Bregman distances in Banach spaces is unified around the notion of Bregman monotonicity. A systematic investigation of this notion leads to a simplified analysis of numerous algorithms and to the development of a new class of parallel block-iterative surrogate Bregman projection schemes. Another key contribution is the introduction of a class of operators that is shown to be intrinsically tied to the notion of Bregman monotonicity and to include the operators commonly found in Bregman optimization methods. Special emphasis is placed on the viability of the algorithms and the importance of Legendre functions in this regard. Various applications are discussed.

273 citations

Journal ArticleDOI
TL;DR: A full understanding of LPS biosynthesis in P. aeruginosa is almost within reach, and knowledge derived from detailed studies in the O5, O6 and O11 serotypes is applied to predict biosynthesis pathways of sugars in poorly-studied serotypes.
Abstract: Pseudomonas aeruginosa causes serious nosocomial infections, and an important virulence factor produced by this organism is lipopolysaccharide (LPS). This review summarizes knowledge about biosynthesis of all three structural domains of LPS - lipid A, core oligosaccharide, and O polysaccharides. In addition, based on similarities with other bacterial species, this review proposes new hypothetical pathways for unstudied steps in the biosynthesis of P. aeruginosa LPS. Lipid A biosynthesis is discussed in relation to Escherichia coli and Salmonella, and the biosyntheses of core sugar precursors and core oligosaccharide are summarised. Pseudomonas aeruginosa attaches a Common Polysaccharide Antigen and O-Specific Antigen polysaccharides to lipid A-core. Both forms of O polysaccharide are discussed with respect to their independent synthesis mechanisms. Recent advances in understanding O-polysaccharide biosynthesis since the last major review on this subject, published nearly a decade ago, are highlighted. Since P. aeruginosa O polysaccharides contain unusual sugars, sugar-nucleotide biosynthesis pathways are reviewed in detail. Knowledge derived from detailed studies in the O5, O6 and O11 serotypes is applied to predict biosynthesis pathways of sugars in poorly-studied serotypes, especially O1, O4, and O13/O14. Although further work is required, a full understanding of LPS biosynthesis in P. aeruginosa is almost within reach.

273 citations

Journal ArticleDOI
TL;DR: A survey of 635 Canadian men and women revealed that overall attitudes toward Canadian-made products were positive, especially among women as discussed by the authors, while European wines were rated ahead of Canadian wines.
Abstract: A survey of 635 Canadian men and women revealed that overall attitudes toward Canadian-made products were positive, especially among women. Cynicism existed among men and among persons who were older, had higher educations, higher incomes and higher status occupations. For clothing and footwear products Canadian-made rated high, but Japanese-made rated higher for automobiles and home entertainment equipment, while European wines were rated ahead of Canadian wines. The last purchase in each product category studied was frequently Canadian-made. Consumers favored purchasing Canadian-made products in the future except for home entertainment equipment. Implications for Canadian industry, marketing and government policy are drawn.

273 citations


Authors

Showing all 26778 results

NameH-indexPapersCitations
Dirk Inzé14964774468
Norbert Perrimon13861073505
Bobby Samir Acharya1331121100545
Eduardo Marbán12957949586
Benoît Roux12049362215
Fereidoon Shahidi11995157796
Stephen Safe11678460588
Mark A. Tarnopolsky11564442501
Robert C. Haddon11257752712
Milton H. Saier11170754496
Hans J. Vogel111126062846
Paul D. N. Hebert11153766288
Peter T. Katzmarzyk11061856484
John Campbell107115056067
Linda F. Nazar10631852092
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202368
2022391
20212,575
20202,547
20192,264
20182,155